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Structural equation modelling (SEM) is a multivariate statistical technique for estimating complex relationships between observed and latent variables. Although numerous SEM packages exist, each of them has limitations. Some packages are…

Applications · Statistics 2021-06-02 Meshcheryakov Georgy , Igolkina Anna

Structural equation modeling (SEM) is a popular tool in the social and behavioural sciences, where it is being applied to ever more complex data types. The high-dimensional data produced by modern sensors, brain images, or (epi)genetic…

Methodology · Statistics 2019-10-11 Erik-Jan van Kesteren , Daniel L. Oberski

Ecologists and evolutionary biologists are relying on an increasingly sophisticated set of statistical tools to describe complex natural systems. One such tool that has gained increasing traction in the life sciences is structural equation…

Quantitative Methods · Quantitative Biology 2015-09-08 Jonathan S. Lefcheck

The Simulation Environment for Atomistic and Molecular Modeling (SEAMM) is an open-source software package written in Python that provides a graphical interface for setting up, executing, and analyzing molecular and materials simulations.…

Structural Equation Models (SEMs) are routinely used in the analysis of empirical data by researchers from different scientific fields such as psychologists or economists. In some fields, such as in ecology, SEMs have only started recently…

Applications · Statistics 2019-01-09 Lionel R. Hertzog

Structural Equation Modeling (SEM) or Covariance Structure Analysis (CSA) is a versatile and powerful method in the social and behavioral sciences, providing a framework for modeling complex relationships, testing mediation, accounting for…

Applications · Statistics 2025-04-01 Bang Quan Zheng

This paper provides a tutorial discussion on analyzing structural equation modelling (SEM). SEM can be regarded as regression models with observed and unobserved indicators, have been extensively applied to practical and fundamental…

Methodology · Statistics 2015-04-15 Hashem Salarzadeh Jenatabadi

SEMMS (Scalable Empirical-Bayes Model for Marker Selection) is a variable-selection procedure for generalized linear models that uses a three-component normal mixture prior on regression coefficients. In its original form, SEMMS assumes…

Computation · Statistics 2026-03-18 Haim Bar , Martin T. Wells

Structural Equation Modeling (SEM) is a flexible statistical technique with multiple applications, including behavioral genetics and social sciences. Building on the original design of the umx package, which improved accessibility to OpenMx…

Applications · Statistics 2026-02-10 Luis FS Castro-de-Araujo , Nathan Gillespie , Michael C Neale , Timothy Bates

Structural equation models comprise a large class of popular statistical models, including factor analysis models, certain mixed models, and extensions thereof. Model estimation is complicated by the fact that we typically have multiple…

Computation · Statistics 2022-03-18 Edgar C. Merkle , Ellen Fitzsimmons , James Uanhoro , Ben Goodrich

While it is well known that high levels of prenatal alcohol exposure (PAE) result in significant cognitive deficits in children, the exact nature of the dose response is less well understood. In particular, there is a pressing need to…

A new method for estimating structural equation models (SEM) is proposed and evaluated. In contrast to most other methods, it is based directly on the data, not on the covariance matrix of the data. The new approach is flexible enough to…

Methodology · Statistics 2021-10-22 Reinhard Oldenburg

The interpretation of the experimental data collected by testing systems across input datasets and model parameters is of strategic importance for system design and implementation. In particular, finding relationships between variables and…

Information Retrieval · Computer Science 2018-06-26 Massimo Melucci

Randomized controlled trials are a cornerstone of medicine and the social sciences as they enable reliable estimates of causal effects. However, they are costly and time-consuming to conduct, motivating interest in predicting causal effects…

Factor-based Structural Equation Modeling (SEM) relies on likelihood-based estimation assuming a nonsingular sample covariance matrix, which breaks down in small-sample settings with $p>n$. To address this, we propose a novel estimation…

Machine Learning · Computer Science 2026-04-21 Hiroki Hasegawa , Aoba Tamura , Yukihiko Okada

A statistical model is a mathematical representation of an often simplified or idealised data-generating process. In this paper, we focus on a particular type of statistical model, called linear mixed models (LMMs), that is widely used in…

Methodology · Statistics 2020-01-23 Emi Tanaka , Francis K. C. Hui

With the advent of high-throughput sequencing (HTS) in molecular biology and medicine, the need for scalable statistical solutions for modeling complex biological systems has become of critical importance. The increasing number of platforms…

Molecular Networks · Quantitative Biology 2022-10-19 Fernando Palluzzi , Mario Grassi

Structured embedding transformations offer a promising approach for enhancing the efficiency and coherence of language model inference. The introduction of Structural Embedding Projection (SEP) provides a mechanism for refining token…

Computation and Language · Computer Science 2025-08-11 Vincent Enoasmo , Cedric Featherstonehaugh , Xavier Konstantinopoulos , Zacharias Huntington

Probabilistic embeddings have several advantages over deterministic embeddings as they map each data point to a distribution, which better describes the uncertainty and complexity of data. Many works focus on adjusting the distribution…

Artificial Intelligence · Computer Science 2024-12-16 Xiang Huang , Hao Peng , Li Sun , Hui Lin , Chunyang Liu , Jiang Cao , Philip S. Yu

Mixed effects (ME) models inform a vast array of problems in the physical and social sciences, and are pervasive in meta-analysis. We consider ME models where the random effects component is linear. We then develop an efficient approach for…

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