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Frailty is a geriatric syndrome associated with the lack of physiological reserve and consequent adverse outcomes (therapy complications and death) in older adults. Recent research has shown associations between heart rate (HR) dynamics (HR…
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which are also essential to reproduce the synchronous activity of the heart, are: i) accounting for the interaction between the heart and the circulatory…
The refractory period of cardiac tissue can be quantitatively described using strength-interval (SI) curves. The information captured in SI curves is pertinent to the design of anti-arrhythmic devices including pacemakers and implantable…
Atherosclerosis is a chronic inflammatory disease of the artery wall. The early stages of atherosclerosis are driven by interactions between lipids and monocyte-derived-macrophages (MDMs). The mechanisms that govern the spatial distribution…
While ventricular electromechanics is extensively studied, four-chamber heart models have only been addressed recently; most of these works however neglect atrial contraction. Indeed, as atria are characterized by a complex physiology…
The impact of increased stiffness and pulsatile load on the circulation and their influence on heart performance have been documented not only for cardiovascular events but also for ventricular dysfunctions. For this reason, computer models…
The value of a locally frozen magnetic field in a region with a diameter of 0.5 mm in a 0.5-mm-thick YBa2Cu3O7-x plate was investigated as a function of the excitation field (to 2x10^4 A/m), plate cooling mode (in the absence or presence of…
We study the transient dynamics of a viscous liquid contained in a narrow gap between a rigid surface and a parallel elastic plate. The elastic plate is deformed due to an externally applied time-varying pressure-field. We model the…
Multiphysics and multiscale mathematical models enable the non-invasive study of cardiac function. These models often rely on simplifying assumptions that neglect certain biophysical processes to balance fidelity and computational cost. In…
Low-energy excitations play a key role in all condensed-matter systems, yet there is limited understanding of their nature in glasses, where they correspond to local rearrangements of groups of particles. Here we introduce an algorithm to…
The interplay between structural and electrical changes in the heart after myocardial infarction (MI) plays a key role in the initiation and maintenance of arrhythmia. The anatomical and electrophysiological properties of scar, border zone,…
Spatiotemporal patterns in multicellular systems are important to understanding tissue dynamics, for instance, during embryonic development and disease. Here, we use a multiphase field model to study numerically the behavior of a…
The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning…
Magneto-active elastomers (MAEs) are polymer composites consisting of magnetic microparticles embedded in an elastomeric matrix. These materials exhibit strong magneto-mechanical coupling under external magnetic fields, resulting in tunable…
The influence of fatiguing stimuli applied to the quadriceps femoris on the tremor of the index finger on sixteen healthy subjects has been investigated, by measuring the acceleration and the electromyography activity of the extensor…
Numerical simulations have been extensively used in the past two decades for the study of intracranial aneurysms (IAs), a dangerous disease that occurs in the arteries that reach the brain. They may affect up to 10 % of the world's…
The paper reports on a study of electron-phonon interaction within a limited nanosized region. We invoked the modified Fr\"{o}hlich's Hamiltonian to calculate the electron self-energy, as well as the elastic and inelastic scattering cross…
The present effort explores the influence of a longitudinal applied electric field on the magnetocaloric properties of graphenes. The magnetic entropy change $\Delta S(T,\Delta B,E)$ has two contributions: $S_{cos}(T,B,E)$ with an…
This paper deals with the mathematical modelling of large strain electro-viscoelastic deformations in electro-active polymers. Energy dissipation is assumed to occur due to mechanical viscoelasticity of the polymer as well as due to…
This paper presents a nonlinear reaction-diffusion-fluid system that simulates radiofrequency ablation within cardiac tissue. The model conveys the dynamic evolution of temperature and electric potential in both the fluid and solid regions,…