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Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy

Recent studies have shown that multi-modeling methods can provide new insights into the analysis of brain components that are not possible when each modality is acquired separately. The joint representations of different modalities is a…

Neurons and Cognition · Quantitative Biology 2022-01-24 Jalal Mirakhorli

Understanding how anatomical shapes evolve in response to developmental covariates and quantifying their spatially varying uncertainties is critical in healthcare research. Existing approaches typically rely on global time-warping…

Current studies about motor imagery based rehabilitation training systems for stroke subjects lack an appropriate analytic method, which can achieve a considerable classification accuracy, at the same time detects gradual changes of imagery…

Machine Learning · Statistics 2014-09-19 Hao Zhang , Liqing Zhang

Purpose: Computational head models are essential tools for studying the risk of mild traumatic brain injury (mTBI) under different activities and across populations. However, different computational models incorporate varied levels of…

Tissues and Organs · Quantitative Biology 2025-11-07 Anu Tripathi , Alison Brooks , Traci Snedden , Peter Ferrazzano , Christian Franck , Rika Wright Carlsen

Strain and strain rate are effective traumatic brain injury predictors. Kinematics-based models estimating these metrics suffer from significant different distributions of both kinematics and the injury metrics across head impact types. To…

Quantitative Methods · Quantitative Biology 2022-12-07 Xianghao Zhan , Yuzhe Liu , Nicholas J. Cecchi , Olivier Gevaert , Michael M. Zeineh , Gerald A. Grant , David B. Camarillo

Neuroimaging measures of the brain's white matter connections can enable the prediction of non-imaging phenotypes, such as demographic and cognitive measures. Existing works have investigated traditional microstructure and connectivity…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Wan Liu , Yuqian Chen , Chuyang Ye , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight…

Image and Video Processing · Electrical Eng. & Systems 2019-07-18 Jalal Mirakhorli , Hamidreza Amindavar , Mojgan Mirakhorli

Head motion induced by impacts has been deemed as one of the most important measures in brain injury prediction, given that the majority of brain injury metrics use head kinematics as input. Recently, researchers have focused on using fast…

Quantitative Methods · Quantitative Biology 2020-12-11 Patricio Arrue , Nima Toosizadeh , Hessam Babaee , Kaveh Laksari

Emotion recognition based on Electroencephalography (EEG) has gained significant attention and diversified development in fields such as neural signal processing and affective computing. However, the unique brain anatomy of individuals…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Yihang Dong , Xuhang Chen , Yanyan Shen , Michael Kwok-Po Ng , Tao Qian , Shuqiang Wang

The human brain is organized as a complex network, where connections between regions are characterized by both functional connectivity (FC) and structural connectivity (SC). While previous studies have primarily focused on network-level…

Abnormal cortical folding patterns may be related to neurodevelopmental disorders such as lissencephaly and polymicrogyria. In this context, computational modeling is a powerful tool to provide a better understanding of the early brain…

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Plasticity after stroke is a complex phenomenon initiated by the functional reorganization of the brain, especially in the perilesional tissue. At macroscales, the reestablishment of segregation within the affected hemisphere and…

Neurons and Cognition · Quantitative Biology 2022-04-26 Catalina Obando , Charlotte Rosso , Joshua Siegel , Maurizio Corbetta , Fabrizio De Vico Fallani

Recent advancements in medicine have confirmed that brain disorders often comprise multiple subtypes of mechanisms, developmental trajectories, or severity levels. Such heterogeneity is often associated with demographic aspects (e.g., sex)…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Magdalini Paschali , Yu Hang Jiang , Spencer Siegel , Camila Gonzalez , Kilian M. Pohl , Akshay Chaudhari , Qingyu Zhao

Brain tissue accommodates non-linear deformations and exhibits time-dependent mechanical behaviour. The latter is one of the most pronounced features of brain tissue, manifesting itself primarily through viscoelastic effects such as stress…

Soft Condensed Matter · Physics 2025-12-23 G. Small , F. Ballatore , C. Giverso , V. Balbi

Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato