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The human lung is a complex respiratory organ, consisting of five distinct anatomic compartments called lobes. Accurate and automatic segmentation of these pulmonary lobes from computed tomography (CT) images is of clinical importance for…

Image and Video Processing · Electrical Eng. & Systems 2019-09-18 Hoileong Lee , Tahreema Matin , Fergus Gleeson , Vicente Grau

While remarkable advances have been made in Computed Tomography (CT), capturing CT images with non-standardized protocols causes low reproducibility regarding radiomic features, forming a barrier on CT image analysis in a large scale.…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Md Selim , Jie Zhang , Baowei Fei , Guo-Qiang Zhang , Jin Chen

Motion estimation of organs in a sequence of images is important in numerous medical imaging applications. The focus of this paper is the analysis of 4D Respiratory Correlated Computed Tomography (RCCT) Imaging. It is hypothesized that the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Markus D. Foote , Pouya Sabouri , Amit Sawant , Sarang C. Joshi

Purpose: To estimate the total lung volume (TLV) from real and synthetic frontal chest radiographs (CXR) on a pixel level using lung thickness maps generated by a U-Net deep learning model. Methods: This retrospective study included 5,959…

Purpose: This study evaluates the impact of harmonization and multi-region feature integration on survival prediction in non-small cell lung cancer (NSCLC) patients. We assess the prognostic utility of handcrafted radiomics and pretrained…

Purpose: The main purpose of this study was to assess the reliability of shape and heterogeneity features in both Positron Emission Tomography (PET) and low-dose Computed Tomography (CT) components of PET/CT. A secondary objective was to…

Computer Vision and Pattern Recognition · Computer Science 2016-10-06 Marie-Charlotte Desseroit , Florent Tixier , Wolfgang Weber , Barry A Siegel , Catherine Cheze Le Rest , Dimitris Visvikis , Mathieu Hatt

We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Kushal Mehta , Arshita Jain , Jayalakshmi Mangalagiri , Sumeet Menon , Phuong Nguyen , David R. Chapman

Lung cancer remains the leading cause of cancer-related mortality worldwide, with survival strongly dependent on early detection. Standard-dose computed tomography (CT) screening using the Lung Imaging Reporting and Data System (Lung-RADS)…

Background: Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and dangerous pulmonary diseases in the world. It is forecasted that COPD will be the third deadly disease in the future. Therefore, developing…

Medical Physics · Physics 2016-05-30 Mohammad-Parsa Hosseini , Hamid Soltanian-Zadeh , Shahram Akhlaghpoor

Pulmonary emphysema, the progressive, irreversible loss of lung tissue, is conventionally categorized into three subtypes identifiable on pathology and on lung computed tomography (CT) images. Recent work has led to the unsupervised…

In lung radiotherapy, the primary objective is to optimize treatment outcomes by minimizing exposure to healthy tissues while delivering the prescribed dose to the target volume. The challenge lies in accounting for lung tissue motion due…

Medical Physics · Physics 2024-11-26 Frederic Madesta , Lukas Wimmert , Tobias Gauer , René Werner , Thilo Sentker

In CT-based evaluation of the extent of cystic changes in the lungs of patients with cystic lung diseases, such as Lymphangioleiomyomatosis (LAM), there is a lack of a lung phantom containing air-filled cavities that mimic pulmonary cysts…

Medical Physics · Physics 2025-03-26 Shefra Shah , Farah Hussaini , Dumitru Mazilu , Eric E. Bennett , Han Wen

For the one billion sufferers of respiratory disease, managing their disease with inhalers crucially influences their quality of life. Generic treatment plans could be improved with the aid of computational models that account for…

As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past a few years. Recent studies in radiomics aim to investigate the relationship between tumors imaging features and…

Quantitative Methods · Quantitative Biology 2019-07-11 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

Classical radiomic features have been designed to describe image appearance and intensity patterns. These features are directly interpretable and readily understood by radiologists. Compared with end-to-end deep learning (DL) models, lower…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Yaxi Chen , Simin Ni , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Purpose: To identify optimal classification methods for computed tomography (CT) radiomics-based preoperative prediction of clear cells renal cell carcinoma (ccRCC) grade. Methods and material: Seventy one ccRCC patients were included in…

Accurate delineation of pathological lungs from computed tomography (CT) images remains mostly unsolved because available methods fail to provide a reliable generic solution due to high variability of abnormality appearance. Local…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Awais Mansoor , Ulas Bagci , Daniel J. Mollura

Before the recent success of deep learning methods for automated medical image analysis, practitioners used handcrafted radiomic features to quantitatively describe local patches of medical images. However, extracting discriminative…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Yan Han , Gregory Holste , Ying Ding , Ahmed Tewfik , Yifan Peng , Zhangyang Wang

Quantitative extraction of high-dimensional mineable data from medical images is a process known as radiomics. Radiomics is foreseen as an essential prognostic tool for cancer risk assessment and the quantification of intratumoural…

Identifying image features that are robust with respect to segmentation variability and domain shift is a tough challenge in radiomics. So far, this problem has mainly been tackled in test-retest analyses. In this work we analyze radiomics…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Christoph Haarburger , Justus Schock , Daniel Truhn , Philippe Weitz , Gustav Mueller-Franzes , Leon Weninger , Dorit Merhof