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Spiculations are important predictors of lung cancer malignancy, which are spikes on the surface of the pulmonary nodules. In this study, we proposed an interpretable and parameter-free technique to quantify the spiculation using area…

Computer Vision and Pattern Recognition · Computer Science 2020-10-16 Wookjin Choi , Saad Nadeem , Sadegh Riyahi , Joseph O. Deasy , Allen Tannenbaum , Wei Lu

Objective: Lung cancer is a leading cause of cancer-related mortality worldwide, primarily due to delayed diagnosis and poor early detection. This study aims to develop a computer-aided diagnosis (CAD) system that leverages large…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Hafza Eman , Furqan Shaukat , Muhammad Hamza Zafar , Syed Muhammad Anwar

Automated segmentation of Lungs plays a crucial role in the computer-aided diagnosis of chest X-Ray (CXR) images. Developing an efficient Lung segmentation model is challenging because of difficulties such as the presence of several edges…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Jyoti Islam , Yanqing Zhang

Cardiopulmonary exercise testing (CPET) provides a comprehensive assessment of functional capacity by measuring key physiological variables including oxygen consumption ($VO_2$), carbon dioxide production ($VCO_2$), and pulmonary…

Machine Learning · Computer Science 2025-03-19 Muhammet Alkan , Gruschen Veldtman , Fani Deligianni

This work proposed a novel deep registration pipeline for 3D CT and 2D U/S kidney scans of free breathing, which consists of a feature network, and a 3D-2D CNN-based registration network. The feature network has handcraft texture feature…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Chi Yanling , Xu Yuyu , Liu Huiying , Wu Xiaoxiang , Liu Zhiqiang , Mao Jiawei , Xu Guibin , Huang Weimin

Purpose: Analysis of [18F]-Fluorodeoxyglucose (FDG) kinetics in cancer has been most often limited to the evaluation of the average uptake over relatively large volumes. Nevertheless, tumor lesion almost contains inflammatory infiltrates…

Early and accurate diagnosis of interstitial lung diseases (ILDs) is crucial for making treatment decisions, but can be challenging even for experienced radiologists. The diagnostic procedure is based on the detection and recognition of the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Marios Anthimopoulos , Stergios Christodoulidis , Lukas Ebner , Thomas Geiser , Andreas Christe , Stavroula Mougiakakou

Computed tomography imaging is a standard modality for detecting and assessing lung cancer. In order to evaluate the malignancy of lung nodules, clinical practice often involves expert qualitative ratings on several criteria describing a…

Computer Vision and Pattern Recognition · Computer Science 2016-09-22 Mario Buty , Ziyue Xu , Mingchen Gao , Ulas Bagci , Aaron Wu , Daniel J. Mollura

Introduction: Lung cancer is a leading cause of cancer-related mortality, and stereotactic body radiotherapy (SBRT) has become a standard treatment for early-stage lung cancer. However, the heterogeneous response to radiation at the tumor…

Much of the information of breathing is contained within the photoplethysmography (PPG) signal, through changes in venous blood flow, heart rate and stroke volume. We aim to leverage this fact, by employing a novel deep learning framework…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Harry J. Davies , Danilo P. Mandic

Machine learning methods with quantitative imaging features integration have recently gained a lot of attention for lung nodule classification. However, there is a dearth of studies in the literature on effective features ranking methods…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Hina Shakir , Haroon Rasheed , Tariq Mairaj Rasool Khan

Radiomics is a promising technology that focuses on improvements of image analysis, using an automated high-throughput extraction of quantitative features. However, the character of lesion is affected by the surrounding tissue. A lesion on…

Quantitative Methods · Quantitative Biology 2021-11-12 Takuma Usuzaki , Kengo Takahash , Kazuma Umemiya

Non-small-cell lung cancer (NSCLC) represents approximately 80-85% of lung cancer diagnoses and is the leading cause of cancer-related death worldwide. Recent studies indicate that image-based radiomics features from positron emission…

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an…

Computational Engineering, Finance, and Science · Computer Science 2023-05-10 Carolin M. Geitner , Tobias Becher , Inéz Frerichs , Norbert Weiler , Jason H. T. Bates , Wolfgang A. Wall

While the acute phase of the COVID-19 pandemic has subsided, its long-term effects persist through Post-Acute Sequelae of COVID-19 (PASC), commonly known as Long COVID. There remains substantial uncertainty regarding both its duration and…

3D echocardiography is an increasingly popular tool for assessing cardiac remodelling in the right ventricle (RV). It allows quantification of the cardiac chambers without any geometric assumptions, which is the main weakness of 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Gabriel Bernardino , Amir Hodzic , Helene Langet , Damien LeGallois , Mathieu De Craene , Miguel Angel González Ballester , Eric Saloux , Bart Bijnens

While foundation models in radiology are expected to be applied to various clinical tasks, computational cost constraints remain a major challenge when training on 3D-CT volumetric data. In this study, we propose TotalFM, a radiological…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Kohei Yamamoto , Tomohiro Kikuchi

X-Ray imaging is quick, cheap and useful for front-line care assessment and intra-operative real-time imaging (e.g., C-Arm Fluoroscopy). However, it suffers from projective information loss and lacks vital volumetric information on which…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Athanasios Vlontzos , Samuel Budd , Benjamin Hou , Daniel Rueckert , Bernhard Kainz

Aim: In the present work, we aimed to evaluate a comprehensive radiomics framework that enabled prediction of EGFR and KRAS mutation status in NSCLC cancer patients based on PET and CT multi-modalities radiomic features and machine learning…

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