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Optimizing laser and plasma parameters is crucial for enhancing accelerated proton energy in laser-driven proton acceleration with finite laser energy for applications such as cancer therapy. Tight focusing plays a significant role in…

Plasma Physics · Physics 2026-04-10 Guanqi Qiu , Qianyi Ma , Deji Liu , Dongchi Cai , Zheng Gong , Yinren Shou , Jinqing Yu , Xueqing Yan

The use of a ccelerators for medical applications has evolved from initial experimentation to turn-key devices commonly operating in hospitals. New applications are continuously being developed around the world, and the hadrontherapy…

Accelerator Physics · Physics 2016-01-21 C. Biscari , L. Falbo

Given that there are 94 clinics and more than 200,000 patients treated worldwide, proton and carbon are the most used heavily charged particles in heavy ion therapy. However, there is a recent increasing trend in using new ion beams. Each…

Medical Physics · Physics 2021-01-26 Fatih Ekinci , Erkan Bostanci , Ozlem Dagli , Mehmet Serdar Guzel

Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…

Radiotherapy, due to its technology-intensive nature and reliance on digital data and human-machine interactions, is particularly suited to benefit from artificial intelligence (AI) to improve the accuracy and efficiency of its clinical…

Medical Physics · Physics 2021-02-08 Chao Wu , Dan Nguyen , Jan Schuemann , Andrea Mairani , Yuehu Pu , Steve Jiang

We demonstrate an ion acceleration scheme capable of simultaneously focusing and accelerating a multispecies ion beam with monoenergetic spectra to a few micron radius. The focal length and ion mean energy can be independently controlled:…

Plasma Physics · Physics 2025-02-21 Jihoon Kim , Roopendra Rajawat , Tianhong Wang , Gennady Shvets

A new regime is described for Radiation Pressure Acceleration of a thin foil by an intense laser beam of above 10^20 W/cm^2. Highly monoenergetic proton beams extending to GeV energies can be produced with very high efficiency using…

Plasma Physics · Physics 2009-11-13 A. P. L. Robinson , M. Zepf , S. Kar , R. G. Evans , C. Bellei

We present a novel laser based ion acceleration scheme, where a petawatt circularly polarized laser pulse is shot on an ultra-thin (nano-scale) double-layer target. Our scheme allows the production of high-quality light ion beams with both…

Plasma Physics · Physics 2013-09-06 M. Grech , S. Skupin , R. Nuter , L. Gremillet , E. Lefebvre

In order to achieve a high quality, i. e. monoergetic, intense ion beam, we propose the use of a double layer target. The first layer, at the target front, consists of high-Z atoms, while the second (rear) layer is a thin coating of low-Z…

A remarkable ion energy increase is demonstrated by several-stage post-acceleration in a laser plasma interaction. Intense short-pulse laser generates a strong current by high-energy electrons accelerated, when an intense short-pulse laser…

Plasma Physics · Physics 2012-10-29 S. Kawata , D. Sato , T. Izumiyama , T. Nagashima , D. Barada , W. M. Wang , Q. Kong , P. X. Wang , Z. M. Sheng

The question of whether or not neutron therapy works has been answered. It is a qualified yes, as is the case with all of radiation therapy. But, neutron therapy has not kept pace with the rest of radiation therapy in terms of beam delivery…

Medical Physics · Physics 2014-09-09 Thomas K. Kroc , James S. Welsh

Using a kilojoule class laser, we demonstrate for the first time that high-contrast picosecond pulses are advantageous for ion acceleration. We show that a laser pulse with optimum duration and a large focal spot accelerates electrons…

We propose a multi-scale approach to understand the physics related to ion-beam cancer therapy. It allows the calculation of the probability of DNA damage as a result of irradiation of tissues with energetic ions, up to 430 MeV/u. This…

Biological Physics · Physics 2009-11-13 Andrey V. Solov'yov , Eugene Surdutovich , Emanuele Scifoni , Igor Mishustin , Walter Grainer

The two dominant radiotherapy methods are either simplified in terms of beam generation and handling, which compromises the energy deposition curve in tissues (photon therapy), or require extensive accelerator facilities and complex beam…

Accelerator Physics · Physics 2023-09-12 Marta Monikowska , Marcin Patecki

Nowadays there is a growing interest in Particle Therapy treatments exploiting light ion beams against tumors due to their enhanced Relative Biological Effectiveness and high space selectivity. In particular promising results are obtained…

The proposed linear accelerator ("scanator") consists of a terawatt table-top laser and a set of passive elements - beam splitters, dispersion elements for stretching of the laser pulse and chirping of the splitted beams, and dispersion…

Accelerator Physics · Physics 2007-05-23 A. I. Dzergatch , S. V. Vinogradov

A method is proposed for producing monoergetic, high-quality ion beams in vacuum, via direct acceleration by the electromagnetic field of two counterpropagating, variable-frequency lasers: ions are trapped and accelerated by a beat-wave…

Plasma Physics · Physics 2009-05-29 F. Peano , J. Vieira , R. A. Fonseca , R. Mulas , G. Coppa , L. O. Silva

An effective scheme of synchronized laser-triggered ion acceleration and the corresponding theoretical model are proposed for a slow light pulse of relativistic intensity, which penetrates into a near-critical-density plasma, strongly…

Plasma Physics · Physics 2016-03-02 A. V. Brantov , E. A. Govras , V. F. Kovalev , V. Yu. Bychenkov

Intense laser acceleration of ions is inherently difficult due to the velocity mismatch between laser pulses moving at the speed of light and slowly moving massive ions. Instead of directly accelerating the ions, current approaches rely on…

A new approach to the development of extraction systems capable of forming ion beams with previously inaccessible intensity is proposed. The use of inhomogeneous accelerating field allows to improve the ion beam formation efficiency…

Plasma Physics · Physics 2020-12-30 S. S. Vybin , I. V. Izotov. V. A. Skalyga
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