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Objective: Proton spot-scanning arc therapy (ARC) is an emerging modality that can improve the high-dose conformity to targets compared with standard intensity-modulated proton therapy (IMPT). However, the efficient treatment delivery of…

Sparse recovery is one of the most fundamental and well-studied inverse problems. Standard statistical formulations of the problem are provably solved by general convex programming techniques and more practical, fast (nearly-linear time)…

Data Structures and Algorithms · Computer Science 2022-03-09 Jonathan A. Kelner , Jerry Li , Allen Liu , Aaron Sidford , Kevin Tian

The performance of deep (reinforcement) learning systems crucially depends on the choice of hyperparameters. Their tuning is notoriously expensive, typically requiring an iterative training process to run for numerous steps to convergence.…

Machine Learning · Computer Science 2021-01-19 Vu Nguyen , Sebastian Schulze , Michael A Osborne

Predictive models for clinical outcomes that are accurate on average in a patient population may underperform drastically for some subpopulations, potentially introducing or reinforcing inequities in care access and quality. Model training…

Machine Learning · Statistics 2022-02-03 Stephen R. Pfohl , Haoran Zhang , Yizhe Xu , Agata Foryciarz , Marzyeh Ghassemi , Nigam H. Shah

Spatiotemporal fractionation schemes, that is, treatments delivering different dose distributions in different fractions, may lower treatment side effects without compromising tumor control. This is achieved by hypofractionating parts of…

Medical Physics · Physics 2018-02-14 Melissa R. Gaddy , Sercan Yıldız , Jan Unkelbach , Dávid Papp

Patient-specific computational modeling has emerged as a powerful tool for surgical planning in complex congenital heart disease. One promising application is complex biventricular repair, which often requires construction of a custom…

Computational Engineering, Finance, and Science · Computer Science 2026-03-27 Elena Sabdy Martinez , Alexander D. Kaiser , Alexander K. Reed , Sascha W. Stocker , Amit Sharir , Perry S. Choi , Shiraz A. Maskatia , Michael R. Ma , Alison Lesly Marsden

The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…

Medical Physics · Physics 2023-07-27 Amir Moslemi , Navid Khaledi

Purpose: We propose a general framework for quantifying predictive uncertainties of dose-related quantities and leveraging this information in a dose mimicking problem in the context of automated radiation therapy treatment planning.…

Medical Physics · Physics 2021-09-08 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

Novel technologies in automated machine learning ease the complexity of algorithm selection and hyperparameter optimization. Hyperparameters are important for machine learning models as they significantly influence the performance of…

Machine Learning · Computer Science 2021-08-31 Mohamadjavad Bahmani , Radwa El Shawi , Nshan Potikyan , Sherif Sakr

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Flat panel computed tomography is used intraoperatively to assess the result of surgery. Due to workflow issues, the acquisition typically cannot be carried out in such a way that the axis aligned multiplanar reconstructions (MPR) of the…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Celia Martín Vicario , Florian Kordon , Felix Denzinger , Markus Weiten , Sarina Thomas , Lisa Kausch , Jochen Franke , Holger Keil , Andreas Maier , Holger Kunze

Mean arterial blood pressure (MAP) dynamics estimation and its automated regulation could benefit the clinical and emergency resuscitation of critical patients. In order to address the variability and complexity of the MAP response of a…

Systems and Control · Electrical Eng. & Systems 2020-07-09 Shahin Tasoujian , Saeed Salavati , Matthew Franchek , Karolos Grigoriadis

Behavior and motion planning play an important role in automated driving. Traditionally, behavior planners instruct local motion planners with predefined behaviors. Due to the high scene complexity in urban environments, unpredictable…

Robotics · Computer Science 2020-09-15 Sascha Rosbach , Vinit James , Simon Großjohann , Silviu Homoceanu , Stefan Roth

As deep neural networks include a high number of parameters and operations, it can be a challenge to implement these models on devices with limited computational resources. Despite the development of novel pruning methods toward…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Morteza Homayounfar , Mohamad Koohi-Moghadam , Reza Rawassizadeh , Varut Vardhanabhuti

Inverse design is a commonly used methodology for creating devices that manipulate electromagnetic (EM) waves by algorithmically modifying device parameters to achieve a desired functionality. Utilizing plasma, a dynamically tunable medium,…

In the realm of medical science, the pursuit of enhancing treatment efficacy and patient outcomes continues to drive innovation. This study delves into the integration of biomimicry principles within the domain of Radiation Therapy (RT) to…

Neural and Evolutionary Computing · Computer Science 2025-01-07 Keshav Kumar K. , NVSL Narasimham

The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods only use patient anatomy as input and assume consistent beam configuration for all…

Software analytics has been widely used in software engineering for many tasks such as generating effort estimates for software projects. One of the "black arts" of software analytics is tuning the parameters controlling a data mining…

Software Engineering · Computer Science 2019-02-04 Tianpei Xia , Rahul Krishna , Jianfeng Chen , George Mathew , Xipeng Shen , Tim Menzies

We propose a fully automatic method to find standardized view planes in 3D image acquisitions. Standard view images are important in clinical practice as they provide a means to perform biometric measurements from similar anatomical…