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Convolutional Neural Networks (CNNs) work very well for supervised learning problems when the training dataset is representative of the variations expected to be encountered at test time. In medical image segmentation, this premise is…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Neerav Karani , Ertunc Erdil , Krishna Chaitanya , Ender Konukoglu

Formal verification of neural networks is essential for their deployment in safety-critical areas. Many available formal verification methods have been shown to be instances of a unified Branch and Bound (BaB) formulation. We propose a…

Machine Learning · Computer Science 2019-12-04 Jingyue Lu , M. Pawan Kumar

In the field of connectomics, neuroscientists seek to identify cortical connectivity comprehensively. Neuronal boundary detection from the Electron Microscopy (EM) images is often done to assist the automatic reconstruction of neuronal…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Wei Shen , Bin Wang , Yuan Jiang , Yan Wang , Alan Yuille

Microvascular anatomy is known to be involved in various neurological disorders. However, understanding these disorders is hindered by the lack of imaging modalities capable of capturing the comprehensive three-dimensional vascular network…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Etienne Chollet , Yaël Balbastre , Chiara Mauri , Caroline Magnain , Bruce Fischl , Hui Wang

Problems in scientific computing, such as distributing large sparse matrix operations, have analogous formulations as hypergraph partitioning problems. A hypergraph is a generalization of a traditional graph wherein "hyperedges" may connect…

Data Structures and Algorithms · Computer Science 2022-06-16 Justin Sybrandt , Ruslan Shaydulin , Ilya Safro

Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological accuracy. Existing topology-aware methods often lack robust…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Laurin Lux , Alexander H. Berger , Alexander Weers , Nico Stucki , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

Deep convolutional neural networks for image segmentation do not learn the label structure explicitly and may produce segmentations with an incorrect structure, e.g., with disconnected cylindrical structures in the segmentation of tree-like…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Shuai Chen , Antonio Garcia-Uceda , Jiahang Su , Gijs van Tulder , Lennard Wolff , Theo van Walsum , Marleen de Bruijne

Motivation: 3D neuron segmentation is a key step for the neuron digital reconstruction, which is essential for exploring brain circuits and understanding brain functions. However, the fine line-shaped nerve fibers of neuron could spread in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Qiufu Li , Linlin Shen

Visually comparing brain networks, or connectomes, is an essential task in the field of neuroscience. Especially relevant to the field of clinical neuroscience, group studies that examine differences between populations or changes over time…

Neurons and Cognition · Quantitative Biology 2017-07-03 Johnson J. G. Keiriz , Liang Zhan , Morris Chukhman , Olu Ajilore , Alex D. Leow , Angus G. Forbes

Graph Visualization, also known as Graph Drawing, aims to find geometric embeddings of graphs that optimize certain criteria. Stress is a widely used metric; stress is minimized when every pair of nodes is positioned at their shortest path…

Computational Geometry · Computer Science 2024-02-13 Florian Grötschla , Joël Mathys , Robert Veres , Roger Wattenhofer

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

Deep convolutional neural networks have proved effective in segmenting lesions and anatomies in various medical imaging modalities. However, in the presence of small sample size and domain shift problems, these models often produce masks…

Image and Video Processing · Electrical Eng. & Systems 2020-02-04 Nima Tajbakhsh , Brian Lai , Shilpa Ananth , Xiaowei Ding

To accurately understand engineering drawings, it is essential to establish the correspondence between images and their description tables within the drawings. Existing document understanding methods predominantly focus on text as the main…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Chao Gu , Ke Lin , Yiyang Luo , Jiahui Hou , Xiang-Yang Li

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous system has been limited due to various sources of variability…

Neurons and Cognition · Quantitative Biology 2017-01-24 Uygar Sümbül , Douglas Roussien , Fei Chen , Nicholas Barry , Edward S. Boyden , Dawen Cai , John P. Cunningham , Liam Paninski

We describe a method for verifying the output of a deep neural network for medical image segmentation that is robust to several classes of random as well as worst-case perturbations i.e. adversarial attacks. This method is based on a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Fahim Ahmed Zaman , Xiaodong Wu , Weiyu Xu , Milan Sonka , Raghuraman Mudumbai

Recently, link prediction algorithms based on neural embeddings have gained tremendous popularity in the Semantic Web community, and are extensively used for knowledge graph completion. While algorithmic advances have strongly focused on…

Artificial Intelligence · Computer Science 2020-08-31 Asan Agibetov , Matthias Samwald

Automated detection of vulnerabilities in source code is an essential cybersecurity challenge, underpinning trust in digital systems and services. Graph Neural Networks (GNNs) have emerged as a promising approach as they can learn…

Artificial Intelligence · Computer Science 2025-09-10 David Egea , Barproda Halder , Sanghamitra Dutta

Mathematical modeling has broad applications in neuroscience whether modeling the dynamics of a single synapse or an entire network of neurons. In Part I, we model vesicle replenishment and release at the photoreceptor synapse to better…

Neurons and Cognition · Quantitative Biology 2017-02-23 Caitlyn M. Parmelee

Recent advances in high-resolution microscopy have allowed scientists to better understand the underlying brain connectivity. However, due to the limitation that biological specimens can only be imaged at a single timepoint, studying…

Machine Learning · Computer Science 2022-02-03 Saeed Boorboor , Shawn Mathew , Mala Ananth , David Talmage , Lorna W. Role , Arie E. Kaufman

This paper presents an automatic algorithm for the segmentation of areas affected by an acute stroke on the non-contrast computed tomography brain images. The proposed algorithm is designed for learning in a weakly supervised scenario when…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Anna Dobshik , Andrey Tulupov , Vladimir Berikov
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