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Understanding the association between mixtures of environmental toxicants and time-to-pregnancy (TTP) is an important scientific question as sufficient evidence has emerged about the impact of individual toxicants on reproductive health and…

Applications · Statistics 2022-12-13 Abhisek Saha , Rajeshwari Sundaram

The immense production of the chemical industry requires an improved predictive risk assessment that can handle constantly evolving challenges while reducing the dependency of risk assessment on animal testing. Integrating 'omics data into…

Quantitative Methods · Quantitative Biology 2024-12-09 Florian Schunck , Bernhard Kodritsch , Wibke Busch , Martin Krauss , Andreas Focks

Understanding the consequences of the combined effects of multiple stressors-including stress from man-made chemicals is important for conservation management, the ecological risk assessment of chemicals, and many other ecological…

Populations and Evolution · Quantitative Biology 2021-03-01 Benoit Goussen , Cecilie Rendal , David Sheffield , Emma Butler , Oliver R. Price , Roman Ashauer

Abundance estimates from animal point-count surveys require accurate estimates of detection probabilities. The standard model for estimating detection from removal-sampled point-count surveys assumes that organisms at a survey site are…

Populations and Evolution · Quantitative Biology 2019-04-09 Adam Martin-Schwarze , Jarad Niemi , Philip Dixon

Retrospectively ascertained survival time may be subject to recall error. An example of discrete survival time with such recall error is time-to-pregnancy (TTP), the number of months non-contracepting couples require to get pregnant which…

In a tie-breaker design (TBD), subjects with high values of a running variable are given some (usually desirable) treatment, subjects with low values are not, and subjects in the middle are randomized. TBDs are intermediate between…

Methodology · Statistics 2025-05-12 Tim P. Morrison , Art B. Owen

The coupling between evolutionary and ecological changes (eco-evolutionary dynamics) has been shown to be relevant among diverse species, and is also of interest outside of ecology, i.e. in cancer evolution. These dynamics play an important…

Analysis of PDEs · Mathematics 2026-01-21 Manh Hong Duong , Fabian Spill , Blaine van Rensburg

Studies of the relationships between environmental exposures and adverse health outcomes often rely on a two-stage statistical modeling approach, where exposure is modeled/predicted in the first stage and used as input to a separately fit…

Methodology · Statistics 2022-04-01 Saskia Comess , Howard H. Chang , Joshua L. Warren

Ecological systems are governed by complex interactions which are mainly nonlinear. In order to capture this complexity and nonlinearity, statistical models recently gained popularity. However, although these models are commonly applied in…

Quantitative Methods · Quantitative Biology 2011-07-29 Can Ozan Tan , Uygar Ozesmi , Meryem Beklioglu , Esra Per , Bahtiyar Kurt

Tie-breaker experimental designs are hybrids of Randomized Controlled Trials (RCTs) and Regression Discontinuity Designs (RDDs) in which subjects with moderate scores are placed in an RCT while subjects with extreme scores are…

Methodology · Statistics 2023-01-24 Dan M. Kluger , Art B. Owen

Context: Software Engineering (SE) experiments suffer from threats to validity that may impact their results. Replication allows researchers building on top of previous experiments' weaknesses and increasing the reliability of the findings.…

Software Engineering · Computer Science 2020-04-14 Adrian Santos , Sira Vegas , Fernando Uyaguari , Oscar Dieste , Burak Turhan , Natalia Juristo

In face of climate change and increasing urbanization, the predictive mosquito-borne diseases (MBD) transmission models require constant updates. Thus, is urgent to comprehend the driving forces of this non stationary behavior, observed…

Quantitative Methods · Quantitative Biology 2024-11-22 Marcio Maciel Bastos , Luiz Max Carvalho , Eduardo Correa Araujo , Flávio Codeço Coelho

This article shows how to specify and construct a discrete, stochastic, continuous-time model specifically for ecological systems. The model is more broad than typical chemical kinetics models in two ways. First, using time-dependent hazard…

Populations and Evolution · Quantitative Biology 2015-06-30 Andrew J. Dolgert

Detecting anomalies has become an increasingly critical function in the financial service industry. Anomaly detection is frequently used in key compliance and risk functions such as financial crime detection fraud and cybersecurity. The…

Machine Learning · Computer Science 2023-12-29 Hongda Shen , Eren Kurshan

Causal effect estimation for dynamic treatment regimes (DTRs) contributes to sequential decision making. However, censoring and time-dependent confounding under DTRs are challenging as the amount of observational data declines over time due…

Machine Learning · Statistics 2021-09-27 Adi Lin , Jie Lu , Junyu Xuan , Fujin Zhu , Guangquan Zhang

Regression discontinuity design (RDD) is a quasi-experimental approach to study the causal effects of an intervention/treatment on later health outcomes. It exploits a continuously measured assignment variable with a clearly defined cut-off…

Applications · Statistics 2024-06-28 Maja Popovic , Daniela Zugna , Lorenzo Richiardi

Predicting the outcomes of species invasions is a central goal of ecology, a task made especially challenging due to ecological feedbacks. To address this, we develop a general theory of ecological invasions applicable to a wide variety of…

Populations and Evolution · Quantitative Biology 2025-08-22 Zhijie Feng , Emmy Blumenthal , Pankaj Mehta , Akshit Goyal

Most population models assume that individuals within a given population are identical, that is, the fundamental role of variation is ignored. Here we develop a general approach to modeling heterogeneous populations with discrete…

Populations and Evolution · Quantitative Biology 2007-05-23 Georgy P. Karev , Artem S. Novozhilov , Faina S. Berezovskaya

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

Training data attribution (TDA) techniques find influential training data for the model's prediction on the test data of interest. They approximate the impact of down- or up-weighting a particular training sample. While conceptually useful,…

Machine Learning · Computer Science 2023-11-01 Elisa Nguyen , Minjoon Seo , Seong Joon Oh
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