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Neurologists typically identify epileptic seizures from electroencephalograms (EEGs) by visual inspection. This process is often time-consuming, especially for EEG recordings that last hours or days. To expedite the process, a reliable,…

Signal Processing · Electrical Eng. & Systems 2022-11-23 Wei Yan Peh , Prasanth Thangavel , Yuanyuan Yao , John Thomas , Yee Leng Tan , Justin Dauwels

Driven by the multi-level structure of human intracranial electroencephalogram (iEEG) recordings of epileptic seizures, we introduce a new variant of a hierarchical Dirichlet Process---the multi-level clustering hierarchical Dirichlet…

Applications · Statistics 2012-06-22 Drausin Wulsin , Shane Jensen , Brian Litt

Deep learning-based methods have shown remarkable effectiveness in solving PDEs, largely due to their ability to enable fast simulations once trained. However, despite the availability of high-performance computing infrastructure, many…

Machine Learning · Computer Science 2026-02-23 Pietro Sittoni , Emanuele Zangrando , Angelo A. Casulli , Nicola Guglielmi , Francesco Tudisco

The applications of traditional statistical feature selection methods to high-dimension, low sample-size data often struggle and encounter challenging problems, such as overfitting, curse of dimensionality, computational infeasibility, and…

Machine Learning · Statistics 2023-12-19 Kexuan Li , Fangfang Wang , Lingli Yang , Ruiqi Liu

In clinical practice, electroencephalography (EEG) plays an important role in the diagnosis of epilepsy. EEG-based computer-aided diagnosis of epilepsy can greatly improve the ac-curacy of epilepsy detection while reducing the workload of…

Signal Processing · Electrical Eng. & Systems 2026-03-24 Andong Li , Zhaohong Deng , Qiongdan Lou

High frequency oscillations (HFOs) are a promising biomarker of epileptic brain tissue and activity. HFOs additionally serve as a prototypical example of challenges in the analysis of discrete events in high-temporal resolution,…

Neurons and Cognition · Quantitative Biology 2017-06-13 Stephen V. Gliske , Kevin R. Moon , William C. Stacey , Alfred O. Hero

Epilepsy is common neurological diseases, affecting about 0.6-0.8 % of world population. Epileptic patients suffer from chronic unprovoked seizures, which can result in broad spectrum of debilitating medical and social consequences. Since…

Quantitative Methods · Quantitative Biology 2017-06-13 Sachin S. Talathi

Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can…

Signal Processing · Electrical Eng. & Systems 2019-11-13 Damian Pascual , Amir Aminifar , David Atienza , Philippe Ryvlin , Roger Wattenhofer

The need for high-quality automated seizure detection algorithms based on electroencephalography (EEG) becomes ever more pressing with the increasing use of ambulatory and long-term EEG monitoring. Heterogeneity in validation methods of…

In the preclinical translational studies, drug candidates with remarkable anti-epileptic efficacy demonstrate long-term suppression of spontaneous recurrent seizures (SRSs), particularly convulsive seizures (CSs), in mouse models of chronic…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Junming Ren , Zhoujian Xiao , Yujia Zhang , Yujie Yang , Ling He , Ezra Yoon , Stephen Temitayo Bello , Xi Chen , Dapeng Wu , Micky Tortorella , Jufang He

Automated epileptic seizure detection from electroencephalogram (EEG) remains challenging due to significant individual differences in EEG patterns across patients. While existing studies achieve high accuracy with patient-specific…

Signal Processing · Electrical Eng. & Systems 2025-05-22 Rina Tazaki , Tomoyuki Akiyama , Akira Furui

The unpredictability of seizures continues to distress many people with drug-resistant epilepsy. On account of recent technological advances, considerable efforts have been made using different hardware technologies to realize smart devices…

Emerging Technologies · Computer Science 2022-02-21 Corey Lammie , Wei Xiang , Mostafa Rahimi Azghadi

Epilepsy is one of the most occurring neurological disease globally emerged back in 4000 BC. It is affecting around 50 million people of all ages these days. The trait of this disease is recurrent seizures. In the past few decades, the…

Machine Learning · Computer Science 2021-11-08 Virender Ranga , Shivam Gupta , Jyoti Meena , Priyansh Agrawal

Image and video descriptors are an omnipresent tool in computer vision and its application fields like mobile robotics. Many hand-crafted and in particular learned image descriptors are numerical vectors with a potentially (very) large…

Computer Vision and Pattern Recognition · Computer Science 2021-01-20 Peer Neubert , Stefan Schubert

Most of the temporal lobe epilepsy detection approaches are based on hippocampus deformation and use complicated features, resulting, detection is done with complicated features extraction and pre-processing task. In this paper, a new…

Computer Vision and Pattern Recognition · Computer Science 2016-12-30 Zohreh Kohan , Hamidreza Farhidzadeh , Reza Azmi , Behrouz Gholizadeh

Automated seizure detection and classification from electroencephalography (EEG) can greatly improve seizure diagnosis and treatment. However, several modeling challenges remain unaddressed in prior automated seizure detection and…

Signal Processing · Electrical Eng. & Systems 2022-03-15 Siyi Tang , Jared A. Dunnmon , Khaled Saab , Xuan Zhang , Qianying Huang , Florian Dubost , Daniel L. Rubin , Christopher Lee-Messer

Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the…

Neurons and Cognition · Quantitative Biology 2011-08-01 Christian Kuehn , Christian Meisel

Complex spatial connectivity patterns, such as interictal suppression and ictal propagation, complicate accurate drug-resistant epilepsy (DRE) seizure detection using stereotactic electroencephalography (SEEG) and traditional machine…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Yiping Wang , Peiren Wang , Zhenye Li , Fang Liu , Jinguo Huang

Epileptic seizure prediction from electroencephalographic (EEG) recordings remains challenging due to strong inter-patient variability and the complex temporal structure of neural signals. This paper presents a patient-adaptive transformer…

Machine Learning · Computer Science 2026-03-31 Mohamed Mahdi , Asma Baghdadi

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…