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Modern drug discovery is often time-consuming, complex and cost-ineffective due to the large volume of molecular data and complicated molecular properties. Recently, machine learning algorithms have shown promising results in virtual…

Neural and Evolutionary Computing · Computer Science 2022-02-08 Dongning Ma , Rahul Thapa , Xun Jiao

Epilepsy is a prevalent neurological disorder affecting 50 million individuals worldwide and 1.2 million Americans. There exist millions of pediatric patients with intractable epilepsy, a condition in which seizures fail to come under…

Machine Learning · Computer Science 2023-09-07 Bliss Singhal , Fnu Pooja

Hyperdimensional computing (HDC) is an emerging computing paradigm that exploits the distributed representation of input data in a hyperdimensional space, the dimensions of which are typically between 1,000--10,000. The hyperdimensional…

Signal Processing · Electrical Eng. & Systems 2024-02-01 Kei Kitagawa , Kohei Tsuji , Koyo Sagehashi , Tomoaki Niiyama , Satoshi Sunada

Machine learning is playing an increasingly important role in medical image analysis, spawning new advances in the clinical application of neuroimaging. There have been some reviews on machine learning and epilepsy before, and they mainly…

Machine Learning · Computer Science 2021-11-03 Jie Yuan , Xuming Ran , Keyin Liu , Chen Yao , Yi Yao , Haiyan Wu , Quanying Liu

Thanks to the tiny storage and efficient execution, hyperdimensional Computing (HDC) is emerging as a lightweight learning framework on resource-constrained hardware. Nonetheless, the existing HDC training relies on various heuristic…

Machine Learning · Computer Science 2022-04-04 Shijin Duan , Yejia Liu , Shaolei Ren , Xiaolin Xu

Publicly available collections of drug-like molecules have grown to comprise 10s of billions of possibilities in recent history due to advances in chemical synthesis. Traditional methods for identifying "hit" molecules from a large…

Epilepsy is the fourth most common neurological disorder, affecting about 1% of the population at all ages. As many as 60% of people with epilepsy experience focal seizures which originate in a certain brain area and are limited to part of…

Machine Learning · Computer Science 2019-03-20 Diyuan Lu , Jochen Triesch

Recognition of epileptic focal point is the important diagnosis when screening the epilepsy patients for latent surgical cures. The accurate localization is challenging one because of the low spatial resolution images with more noisy data.…

Computer Vision and Pattern Recognition · Computer Science 2013-03-05 A. Meena , R. Raja

Ensemble learning is a classical learning method utilizing a group of weak learners to form a strong learner, which aims to increase the accuracy of the model. Recently, brain-inspired hyperdimensional computing (HDC) becomes an emerging…

Neural and Evolutionary Computing · Computer Science 2022-03-28 Ruixuan Wang , Dongning Ma , Xun Jiao

For the past few years, we have developed flexible, active, multiplexed recording devices for high resolution recording over large, clinically relevant areas in the brain. While this technology has enabled a much higher-resolution view of…

Neurons and Cognition · Quantitative Biology 2017-06-06 Yilin Song , Jonathan Viventi , Yao Wang

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

Machine Learning · Computer Science 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Epilepsy is the most common, chronic, neurological disease worldwide and is typically accompanied by reoccurring seizures. Neuro implants can be used for effective treatment by suppressing an upcoming seizure upon detection. Due to the…

Signal Processing · Electrical Eng. & Systems 2025-05-12 Julia Werner , Bhavya Kohli , Paul Palomero Bernardo , Christoph Gerum , Oliver Bringmann

Reliable seizure detection from electroencephalography (EEG) time series is a high-priority clinical goal, yet the acquisition cost and scarcity of labeled EEG data limit the performance of machine learning methods. This challenge is…

Methodology · Statistics 2026-01-30 Nina Moutonnet , Joshua Corneck , Felipe Tobar , Danilo Mandic

Hyperdimensional Computing (HDC) has obtained abundant attention as an emerging non von Neumann computing paradigm. Inspired by the way human brain functions, HDC leverages high dimensional patterns to perform learning tasks. Compared to…

Neural and Evolutionary Computing · Computer Science 2022-07-27 Dongning Ma , Xun Jiao

Hyperdimensional computing (HD) is an emerging paradigm for machine learning based on the evidence that the brain computes on high-dimensional, distributed, representations of data. The main operation of HD is encoding, which transfers the…

Machine Learning · Computer Science 2020-07-22 Behnam Khaleghi , Sahand Salamat , Anthony Thomas , Fatemeh Asgarinejad , Yeseong Kim , Tajana Rosing

The goal of Feature Selection - comprising filter, wrapper, and embedded approaches - is to find the optimal feature subset for designated downstream tasks. Nevertheless, current feature selection methods are limited by: 1) the selection…

Machine Learning · Computer Science 2023-09-18 Meng Xiao , Dongjie Wang , Min Wu , Pengfei Wang , Yuanchun Zhou , Yanjie Fu

In this work, we present a neuromorphic system that combines for the first time a neural recording headstage with a signal-to-spike conversion circuit and a multi-core spiking neural network (SNN) architecture on the same die for recording,…

Signal Processing · Electrical Eng. & Systems 2021-06-09 Mohammadali Sharifshazileh , Karla Burelo , Johannes Sarnthein , Giacomo Indiveri

Epilepsy and psychogenic non-epileptic seizures often present with similar seizure-like manifestations but require fundamentally different management strategies. Misdiagnosis is common and can lead to prolonged diagnostic delays,…

Computation and Language · Computer Science 2026-03-31 Shuang Zhou , Kai Yu , Zaifu Zhan , Huixue Zhou , Min Zeng , Feng Xie , Zhiyi Sha , Rui Zhang

The lack of standardization in seizure forecasting slows progress in the field and limits the clinical translation of forecasting models. In this work, we introduce a Python-based framework aimed at streamlining the development, assessment,…

Quantitative Methods · Quantitative Biology 2025-10-14 Ana Sofia Carmo , Lourenço Abrunhosa Rodrigues , Ana Rita Peralta , Ana Fred , Carla Bentes , Hugo Plácido da Silva

Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially…

Signal Processing · Electrical Eng. & Systems 2020-05-18 Nhan Duy Truong , Yikai Yang , Christina Maher , Armin Nikpour , Omid Kavehei