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Models that can simulate how environments change in response to actions can be used by agents to plan and act efficiently. We improve on previous environment simulators from high-dimensional pixel observations by introducing recurrent…

Artificial Intelligence · Computer Science 2017-04-20 Silvia Chiappa , Sébastien Racaniere , Daan Wierstra , Shakir Mohamed

We present GridFF, an efficient method for simulating molecules on rigid substrates, derived from techniques used in protein-ligand docking in biochemistry. By projecting molecule-substrate interactions onto precomputed spatial grids with…

Chemical Physics · Physics 2025-08-22 Indranil Mal , Milan Kočí , Paolo Nicolini , Prokop Hapala

The Dynamical Graph Grammar (DGG) formalism can describe complex system dynamics with graphs that are mapped into a master equation. An exact stochastic simulation algorithm may be used, but it is slow for large systems. To overcome this…

Quantitative Methods · Quantitative Biology 2024-07-16 Eric Medwedeff , Eric Mjolsness

Artificial neural networks and computational neuroscience models have made tremendous progress, allowing computers to achieve impressive results in artificial intelligence (AI) applications, such as image recognition, natural language…

Neural and Evolutionary Computing · Computer Science 2019-11-05 Giacomo Indiveri , Yulia Sandamirskaya

There is little research concerning comparisons and combination of System Dynamics Simulation (SDS) and Agent Based Simulation (ABS). ABS is a paradigm used in many levels of abstraction, including those levels covered by SDS. We believe…

Computational Engineering, Finance, and Science · Computer Science 2013-05-30 Grazziela P. Figueredo , Uwe Aickelin

Encouraged by the remarkable achievements of language and vision foundation models, developing generalist robotic agents through imitation learning, using large demonstration datasets, has become a prominent area of interest in robot…

Robotics · Computer Science 2024-04-12 Tongzhou Mu , Yijie Guo , Jie Xu , Ankit Goyal , Hao Su , Dieter Fox , Animesh Garg

The two main thrusts of computational science are more accurate predictions and faster calculations; to this end, the zeitgeist in molecular dynamics (MD) simulations is pursuing machine learned and data driven interatomic models, e.g.…

Computational Physics · Physics 2020-02-24 Saaketh Desai , Samuel Temple Reeve , James F. Belak

Due to the very long timescales involved (us-s), theoretical modeling of fundamental biological processes including folding, misfolding, and mechanical unraveling of biomolecules, under physiologically relevant conditions, is challenging…

Soft Condensed Matter · Physics 2010-03-08 A. Zhmurov , R. I. Dima , Y. Kholodov , V. Barsegov

Realistic scene-level multi-agent motion simulations are crucial for developing and evaluating self-driving algorithms. However, most existing works focus on generating trajectories for a certain single agent type, and typically ignore the…

Robotics · Computer Science 2023-11-28 Zhiming Guo , Xing Gao , Jianlan Zhou , Xinyu Cai , Botian Shi

Challenging the Nvidia monopoly, dedicated AI-accelerator chips have begun emerging for tackling the computational challenge that the inference and, especially, the training of modern deep neural networks (DNNs) poses to modern computers.…

Machine Learning · Computer Science 2023-02-01 Lennart P. L. Landsmeer , Max C. W. Engelen , Rene Miedema , Christos Strydis

We present an approach of using AI to model and simulate biology and life. Why is it important? Because at the core of medicine, pharmacy, public health, longevity, agriculture and food security, environmental protection, and clean energy,…

Artificial Intelligence · Computer Science 2024-12-11 Le Song , Eran Segal , Eric Xing

Recent breakthroughs in generative artificial intelligence have triggered a surge in demand for machine learning training, which poses significant cost burdens and environmental challenges due to its substantial energy consumption.…

Artificial Intelligence · Computer Science 2023-04-18 Siyue Zhang , Minrui Xu , Wei Yang Bryan Lim , Dusit Niyato

Large-scale simulation with realistic nonlinear dynamic models is crucial for algorithms development for swarm robotics. However, existing platforms are mainly developed based on Object-Oriented Programming (OOP) and either use simple…

Robotics · Computer Science 2023-08-25 Jinjie Li , Liang Han , Haoyang Yu , Zhaotian Wang , Pengzhi Yang , Ziwei Yan , Zhang Ren

The introduction of accelerator devices such as graphics processing units (GPUs) has had profound impact on molecular dynamics simulations and has enabled order-of-magnitude performance advances using commodity hardware. To fully reap these…

Computational Physics · Physics 2020-10-28 Szilárd Páll , Artem Zhmurov , Paul Bauer , Mark Abraham , Magnus Lundborg , Alan Gray , Berk Hess , Erik Lindahl

LLM-based coding agents can generate functionally correct GPU kernels, yet their performance remains far below hand-optimized libraries on critical computations such as matrix multiplication, attention, and Mixture-of-Experts (MoE). Peak…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-22 Haohui Mai , Xiaoyan Guo , Xiangyun Ding , Daifeng Li , Qiuchu Yu , Chenzhun Guo , Cong Wang , Jiacheng Zhao , Christos Kozyrakis , Binhang Yuan

Training capable Large Language Model (LLM) agents is critically bottlenecked by the high cost and static nature of real-world interaction data. We address this by introducing GenEnv, a framework that establishes a difficulty-aligned…

Computation and Language · Computer Science 2025-12-24 Jiacheng Guo , Ling Yang , Peter Chen , Qixin Xiao , Yinjie Wang , Xinzhe Juan , Jiahao Qiu , Ke Shen , Mengdi Wang

Parallel computing can offer an enormous advantage regarding the performance for very large applications in almost any field: scientific computing, computer vision, databases, data mining, and economics. GPUs are high performance many-core…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-24 Bogdan Oancea , Tudorel Andrei , Raluca Mariana Dragoescu

With large-scale Integral Field Spectroscopy (IFS) surveys of thousands of galaxies currently under-way or planned, the astronomical community is in need of methods, techniques and tools that will allow the analysis of huge amounts of data.…

Instrumentation and Methods for Astrophysics · Physics 2015-12-22 Georgios Bekiaris , Karl Glazebrook , Christopher J. Fluke , Roberto Abraham

This paper presents a new simulator for dynamic modelling of interactions between flooding and people in crowded areas. The simulator is developed in FLAMEGPU (a Flexible Large scale Agent-based Modelling Environment for the GPU), which…

Physics and Society · Physics 2020-03-31 Mohammad Shirvani , Georges Kesserwani , Paul Richmond

It is shown micromagnetic and atomistic spin dynamics simulations can use multiple GPUs in order to reduce computation time, but also to allow for a larger simulation size than is possible on a single GPU. Whilst interactions which depend…

Mesoscale and Nanoscale Physics · Physics 2023-10-12 Serban Lepadatu