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The COVID-19 pandemic left its unique mark on the 21st century as one of the most significant disasters in history, triggering governments all over the world to respond with a wide range of interventions. However, these restrictions come…

Computational Engineering, Finance, and Science · Computer Science 2021-06-02 Assem Zhunis , Tung-Duong Mai , Sundong Kim

COVID-19 has devastated the entire global community. Vaccines present an opportunity to mitigate the pandemic; however, the effect of vaccination coupled with the behavioral response of the population is not well understood. We propose a…

Populations and Evolution · Quantitative Biology 2021-10-26 Thomas Usherwood , Zachary LaJoie , Vikas Srivastava

The unprecedented coronavirus disease 2019 (COVID-19) pandemic is still a worldwide threat to human life since its invasion into the daily lives of the public in the first several months of 2020. Predicting the size of confirmed cases is…

Applications · Statistics 2020-12-02 Xinyu Wang , Lu Yang , Hong Zhang , Zhouwang Yang , Catherine Liu

COVID-19 will be a continuous threat to human population despite having a few vaccines at hand until we reach the endemic state through natural herd immunity and total immunization through universal vaccination. However, the vaccine acts as…

Populations and Evolution · Quantitative Biology 2022-08-26 V. R. Saiprasad , R. Gopal , V. K. Chandrasekar , M. Lakshmanan

This paper presents a study on a compartmental epidemic model for COVID-19, examining the stability of its equilibrium points upon the introduction of vaccination as a strategy to mitigate the spread of the disease. Initially, the SIQR…

Numerical Analysis · Mathematics 2024-05-29 Leonardo R. S. Rodrigues , Felipe Gabrielli

This paper utilizes a stochastic Susceptible-Infected-recovered (SIR) model with a non-linear incidence rate to perform a detailed mathematical study of optimal lock-down intensity and vaccination rate under the COVID-19 pandemic…

Optimization and Control · Mathematics 2022-09-29 Paramahansa Pramanik

Background: By the beginning of December 2020, some vaccines against COVID-19 already presented efficacy and security, which qualify them to be used in mass vaccination campaigns. Thus, setting up strategies of vaccination became crucial to…

Populations and Evolution · Quantitative Biology 2021-02-25 Vinicius V. L. Albani , Jennifer Loria , Eduardo Massad , Jorge P. Zubelli

Social distancing strategies have been adopted by governments to manage the COVID-19 pandemic, since the first outbreak began. However, further epidemic waves keep out the return of economic and social activities to their standard levels of…

Optimization and Control · Mathematics 2021-06-07 J. E. Sereno , A. D' Jorge , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

In this paper we analyze the impact of vaccinations on spread of the COVID-19 virus for different age groups. More specifically we examine the deployment of vaccines in the Nordic countries in a comparative analysis where we analyze factors…

Populations and Evolution · Quantitative Biology 2021-09-24 Anna Sigridur Islind , María Óskarsdóttir , Corentin Cot , Giacomo Cacciapaglia , Francesco Sannino

The investment of time and resources for better strategies and methodologies to tackle a potential pandemic is key to deal with potential outbreaks of new variants or other viruses in the future. In this work, we recreated the scene of a…

Machine Learning · Computer Science 2021-04-22 Andrés L. Suárez-Cetrulo , Ankit Kumar , Luis Miralles-Pechuán

We consider the SEIRS compartment epidemiology model suitable for predicting the evolution of the COVID-19 pandemy in the extreme limiting case of no acquired immunity. The disease-free and endemic fixed points are found and their stability…

Populations and Evolution · Quantitative Biology 2020-12-15 J. M. Ilnytskyi

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

Populations and Evolution · Quantitative Biology 2021-05-18 G. Albi , L. Pareschi , M. Zanella

Social distancing and lockdown are the two main non-pharmaceutical interventions being used by the UK government to contain and control the COVID-19 epidemic; these are being applied uniformly across the entire country, even though the…

Populations and Evolution · Quantitative Biology 2020-04-28 L C G Rogers

During the COVID-19 pandemic, the behavioral response to reported case numbers changed drastically over time. While a few dozen cases were enough to trigger government-induced and voluntary contact reduction in early 2020, less than a year…

Physics and Society · Physics 2023-09-27 Bastian Heinlein , Manlio De Domenico

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

We develop a model of infection spread that takes into account the existence of a vulnerable group as well as the variability of the social relations of individuals. We develop a compartmentalized power-law model, with power-law connections…

Physics and Society · Physics 2020-10-13 Simone Santini

SIR models, also with age structure, can be used to describe the evolution of an infective disease. A vaccination campaign influences this dynamics immunizing part of the susceptible individuals, essentially turning them into recovered…

Analysis of PDEs · Mathematics 2019-10-17 Rinaldo M. Colombo , Mauro Garavello

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

Optimization and Control · Mathematics 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

This research introduces a new approach utilizing optimal control theory (OCT) to assess the Social Optimum (SO) of a vaccination game, navigating the intricate considerations of cost, availability, and distribution policies. By integrating…

Optimization and Control · Mathematics 2025-01-14 Md. Mamun-Ur-Rashid Khan , Jun Tanimoto

This paper introduces a spatiotemporal SEIQR epidemic model governed by a system of reaction-diffusion partial differential equations that incorporates optimal control strategies. The model captures the transmission dynamics of an…

Dynamical Systems · Mathematics 2025-07-29 Achraf Zinihi , Matthias Ehrhardt , Moulay Rchid Sidi Ammi
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