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This work constructs, analyzes, and simulates a new compartmental SEIR-type model for the dynamics and potential control of the current COVID-19 pandemic. The novelty in this work is two-fold. First, the population is divided according to…

Populations and Evolution · Quantitative Biology 2021-05-14 Aycil Cesmelioglu , Kenneth L. Kuttler , Meir Shillor , Anna M. Spagnuolo

We consider the control of the COVID-19 pandemic through a standard SIR compartmental model. This control is induced by the aggregation of individuals' decisions to limit their social interactions: when the epidemic is ongoing, an…

Physics and Society · Physics 2020-06-22 Romuald Elie , Emma Hubert , Gabriel Turinici

In Fall 2020, several European countries reported rapid increases in COVID-19 cases along with growing estimates of the effective reproduction rates. Such an acceleration in epidemic spread is usually attributed to time-dependent effects,…

Populations and Evolution · Quantitative Biology 2022-11-30 Nazmi Burak Budanur , Björn Hof

As of December 2020, the COVID-19 pandemic has infected over 75 million people, making it the deadliest pandemic in modern history. This study develops a novel compartmental epidemiological model specific to the SARS-CoV-2 virus and…

Populations and Evolution · Quantitative Biology 2021-11-19 Caden Lin

The novel COVID-19 pandemic is a current, major global health threat. Up till now, there is no fully approved pharmacological treatment or a vaccine. In this study, simple mathematical models were employed to examine the dynamics of…

Physics and Society · Physics 2020-12-25 Ahmed S. Elgazzar

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

Populations and Evolution · Quantitative Biology 2016-03-29 Chantal Nguyen , Jean M. Carlson

We consider here an extended SIR model, including several features of the recent COVID-19 outbreak: in particular the infected and recovered individuals can either be detected (+) or undetected (-) and we also integrate an intensive care…

Populations and Evolution · Quantitative Biology 2020-05-25 Arthur Charpentier , Romuald Elie , Mathieu Laurière , Viet Chi Tran

This study assesses the impact of COVID-19 vaccines through an epidemiological model that quantifies their role in pandemic control. We analyze an SIR-based model incorporating vaccination effects and calculate the basic reproduction…

Dynamical Systems · Mathematics 2025-07-29 Tesfalem Abate Tegegn , Yibeltal Adane Terefe

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

The mitigation of an infectious disease spreading has recently gained considerable attention from the research community. It may be obtained by adopting sanitary measurements social rules, together with an extensive vaccination campaign.…

Social and Information Networks · Computer Science 2022-02-17 Francesco Petrizzelli , Pietro Hiram Guzzi , Tommaso Mazza

Since COVID-19 vaccines became available, no studies have quantified how different disaster evacuation strategies can mitigate pandemic risks in shelters. Therefore, we applied an age-structured epidemiological model, known as the…

Populations and Evolution · Quantitative Biology 2022-08-30 Yi-Lin Tsai , Dymasius Y. Sitepu , Karyn E. Chappell , Rishi P. Mediratta , C. Jason Wang , Peter K. Kitanidis , Christopher B. Field

The COVID-19 pandemic is the most significant global crisis since World War II that affected almost all the countries of our planet. To control the COVID-19 pandemic outbreak, it is necessary to understand how the virus is transmitted to a…

Populations and Evolution · Quantitative Biology 2022-02-02 Saheb Pal , Indrajit Ghosh

Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…

Populations and Evolution · Quantitative Biology 2020-06-30 Jens Grauer , Hartmut Löwen , Benno Liebchen

In this paper, we propose a dynamical model to describe the transmission of COVID-19, which is spreading in China and many other countries. To avoid a larger outbreak in the worldwide, Chinese government carried out a series of strong…

Populations and Evolution · Quantitative Biology 2020-03-09 Jiwei Jia , Jian Ding , Siyu Liu , Guidong Liao , Jingzhi Li , Ben Duan , Guoqing Wang , Ran Zhang

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

Populations and Evolution · Quantitative Biology 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

A mathematical model of COVID-19 with minimal compartments is developed. The model is simple enough to fit data on confirmed cases, estimate the hidden infection figure and incorporate the effect of vaccination. With the effect of the new…

Populations and Evolution · Quantitative Biology 2021-03-05 Randy L. Caga-anan , Michelle N. Raza , Grace Shelda G. Labrador , Ephrime B. Metillo

The novel coronavirus SARS-CoV-2 and resulting COVID-19 disease have had an unprecedented spread and continue to cause an increasing number of fatalities worldwide. While vaccines are still under development, social distancing, extensive…

Populations and Evolution · Quantitative Biology 2020-07-02 Calvin Tsay , Fernando Lejarza , Mark A. Stadtherr , Michael Baldea

Pandemics can bring a range of devastating consequences to public health and the world economy. Identifying the most effective control strategies has been the imperative task all around the world. Various public health control strategies…

Systems and Control · Electrical Eng. & Systems 2021-03-29 Zhe Xu , Xiaoming Duan

The emergence of coronavirus disease 2019 (COVID-19) in the United States has forced federal and local governments to implement containment measures. Moreover, the severity of the situation has sparked engagement by both the research and…

Populations and Evolution · Quantitative Biology 2020-07-03 Min Lu , Hemant Ishwaran
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