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We present a full-scale clinical prototype system for in vivo range verification of proton pencil-beams using the prompt gamma-ray spectroscopy method. The detection system consists of eight LaBr3 scintillators and a tungsten collimator,…

Irradiation of biological matter triggers a cascade of secondary particles that interact with their surroundings, resulting in damage. Low-energy electrons are one of the main secondary species and electron-phonon interaction plays a…

Chemical Physics · Physics 2017-03-29 Valerio Rizzi , Tchavdar N. Todorov , Jorge J. Kohanoff

This study conceptualizes electronic dose to water, which is the radiation energy imparted to a unit mass of water by electronic interactions. The new dosimetry framework excludes nuclear interactions and consequently associated corrections…

Medical Physics · Physics 2026-03-11 Nobuyuki Kanematsu

Platinum, to date, is the most widely applied electrocatalyst for hydrogen evolution reaction (HER) in acidic media. It is assumed to be a proton-blocking catalyst with only surface-limited adsorption of the reaction intermediates. Here, we…

Chemical Physics · Physics 2025-10-13 Aparna Saksena , Yujun Zhao , J. Manoj Prabhakar , Dierk Raabe , Baptiste Gault , Yug Joshi

The inability of conventional methods to completely remove the contaminants from pharmaceutical effluents led us to study the effect of Electron Beam (EB) irradiation on real pharmaceutical wastewater. In this paper, the samples from…

Carbon ion therapy have the ability to overcome the limitation of convertional radiotherapy due to its most energy deposition in selective depth, usually called Bragg peak, which results in increased biological effectiness. During carbon…

We study the effects of irradiating water with 3 MeV protons at high doses by observing the motion of charged polystyrene beads outside the proton beam. By single-particle tracking, we measure a radial velocity of the order of microns per…

The projector-augmented wave (PAW) method is one of the approaches that are widely used to approximately treat core electrons and thus to speed-up plane-wave basis set electronic structure calculations. However, PAW involves approximations…

Chemical Physics · Physics 2023-08-24 Sirous Yourdkhani , Jiri Klimes

Monitoring physiological and behavioral parameters of laboratory rodents is fundamental for biomedical research, yet conventional techniques often rely on invasive sensors or frequent handling that can induce stress and compromise data…

Signal Processing · Electrical Eng. & Systems 2025-12-08 Tommaso Polonelli , Manuel Glahn , Stefano Kron , Stefan Selbert , Marco Garzola , Michele Magno

Upon illumination by ultraviolet light, many animal species emit light through fluorescence processes arising from fluorophores embedded within their biological tissues. Fluorescence studies in living organisms are however relatively scarce…

Allowed $\beta^+$ branches of very proton-rich $fp$ shell $Tz=-2$ nuclei at the proton drip-line are calculated in the full fp valence space. The $\beta^+$ decay half-lives calculated with the standard quenching factor…

Nuclear Theory · Physics 2009-10-30 E. Caurier , F. Didierjean , F. Nowacki , G. Walter

The use of contrast agents has previously been proposed as a novel method to increase the activation close to the Bragg peak, aiming to improve the quality of proton range monitoring in vivo. In a recent work, we demonstrated the…

Photoacoustic tomography (PAT) is intrinsically sensitive to blood oxygen saturation (sO2) in vivo. However, making accurate sO2 measurements without knowledge of tissue- and instrumentation-related correction factors is extremely…

Medical Physics · Physics 2019-12-17 Marcel Gehrung , Sarah Bohndiek , Joanna Brunker

PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve…

Instrumentation and Detectors · Physics 2015-03-19 A. Miceli , P. Amaudruz , F. Benard , D. A. Bryman , L. Kurchaninov , J. P. Martin , A. Muennich , F. Retiere , T. J. Ruth , V. Sossi , A. J. Stoessl

This study presents the development and validation of a compact device for measuring the water attenuation length (WAL), utilizing photomultiplier tubes (PMTs), optical fibers, and light-emitting diodes (LEDs). An 8 m water tank and the…

Instrumentation and Detectors · Physics 2025-11-03 Junyou Chen , Jilei Xu , Yongbo Huang , Sibo Wang , Chuanshi Dong , Haoqi Lu , Changgen Yang , Yongpeng Zhang , Yi Wang

We propose PET scanners using low atomic number media that undergo a persistent local change of state along the paths of the Compton recoil electrons. Measurement of the individual scattering locations and angles, deposited energies, and…

We propose a new precision measurement of parity-violating electron scattering on the proton at very low Q^2 and forward angles to challenge predictions of the Standard Model and search for new physics. A unique opportunity exists to carry…

JWST is here. The early release observation program (ERO) provides us with the first look at the scientific data and the spectral capabilities. One of the targets from ERO is HAT-P-18b, an inflated Saturn-mass planet with an equilibrium…

The effects of a pulsed low frequency electromagnetic field were investigated on photoluminescence of well characterized water and prepared under controlled conditions (container, atmospheric, electromagnetic, and acoustic environments).…

Chemical Physics · Physics 2016-08-16 Philippe Vallée , Jacques Lafait , Pascale Mentré , Marie-Odile Monod , Yolène Thomas

Organic water-gated thin-film transistors (WG-TFTs) are of great interest in developing low-cost and high-performance biosensors. The device's sensitivity to changes in measurement conditions can impair long-term operation, and care must be…

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