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The dynamics of active viscoelastic surfaces plays an important role in biological systems. One prominent example is the actin cortex, a thin bio-polymer sheet underneath the outer membrane of biological cells which combines active…

The dynamics of membranes, shells and capsules in fluid flow has become an active research area in computational physics and computational biology. The small thickness of these elastic materials enables their efficient approximation as a…

Computational Physics · Physics 2020-10-28 Marcel Mokbel , Sebastian Aland

Fluid deformable surfaces are ubiquitous in cell and tissue biology, including lipid bilayers, the actomyosin cortex, or epithelial cell sheets. These interfaces exhibit a complex interplay between elasticity, low Reynolds number…

Fluid Dynamics · Physics 2019-06-12 Alejandro Torres-Sánchez , Daniel Millán , Marino Arroyo

We consider surface finite elements and a semi-implicit time stepping scheme to simulate fluid deformable surfaces. Such surfaces are modeled by incompressible surface Navier-Stokes equations with bending forces. Here, we consider closed…

Numerical Analysis · Mathematics 2023-05-03 Veit Krause , Axel Voigt

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

Soft Condensed Matter · Physics 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

This work presents a novel numerical investigation of the dynamics of free-boundary flows of viscoelastic liquid membranes. The governing equation describes the balance of linear momentum, in which the stresses include the viscoelastic…

Fluid Dynamics · Physics 2022-04-12 Valeria Barra , Shawn A. Chester , Shahriar Afkhami

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Multiphase systems are ubiquitous in engineering, biology, and materials science, where understanding their complex interactions and rheological behavior is crucial for advancing applications ranging from emulsion stability to cellular…

Fluid Dynamics · Physics 2025-10-27 Andres Santiago Espinosa-Moreno , Nicolas Moreno , Marco Ellero

The paper develops a method for the numerical simulation of a free-surface flow of incompressible viscous fluid around a streamlined body. The body is a rigid stationary construction partially submerged in the fluid. The application we are…

This paper presents a phase-field model for simulating the three-dimensional deformation of vesicle membranes, incorporating area-difference elasticity, with constraints on bulk volume and surface area. We develop efficient numerical…

Numerical Analysis · Mathematics 2025-11-19 Yihong Liang , Emine Celiker , Ping Lin

We consider two-phase fluid deformable surfaces as model systems for biomembranes. Such surfaces are modeled by incompressible surface Navier-Stokes-Cahn-Hilliard-like equations with bending forces. We derive this model using the…

Numerical Analysis · Mathematics 2023-08-03 Elena Bachini , Veit Krause , Ingo Nitschke , Axel Voigt

Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…

Fluid Dynamics · Physics 2021-06-15 Giulia Bertaglia , Valerio Caleffi , Alessandro Valiani

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

Vesicles and many biological membranes are made of two monolayers of lipid molecules and form closed lipid bilayers. The dynamical behaviour of vesicles is very complex and a variety of forms and shapes appear. Lipid bilayers can be…

Computational Physics · Physics 2015-11-11 John W. Barrett , Harald Garcke , Robert Nürnberg

Lipid vesicles appear ubiquitously in biological systems. Understanding how the mechanical and intermolecular interations deform vesicle membrane is a fundamental question in biophysics. In this article we developed a fast algorithm to…

Numerical Analysis · Mathematics 2014-11-17 Michael Mikucki , Y. C. Zhou

Mechanochemical processes on surfaces such as the cellular cortex or epithelial sheets, play a key role in determining patterns and shape changes of biological systems. To understand the complex interplay of hydrodynamics and material flows…

Soft Condensed Matter · Physics 2023-05-04 Lucas D. Wittwer , Sebastian Aland

We describe a numerical method to simulate an elastic shell immersed in a viscous incompressible fluid. The method is developed as an extension of the immersed boundary method using shell equations based on the Kirchhoff-Love and the planar…

Numerical Analysis · Mathematics 2025-10-20 E. Givelberg

This paper presents a novel methodology for the direct numerical modeling and simulation of turbulent flows. The kinetic model equation is firstly extended to turbulent flow with the account of coupled evolution of kinetic, thermal, and…

Computational Physics · Physics 2025-03-11 Xiaojian Yang , Kun Xu

The morphogenesis of cells and tissues involves an interplay between chemical signals and active forces on their surrounding surface layers. The complex interaction of hydrodynamics and material flows on such active surfaces leads to…

Cell Behavior · Quantitative Biology 2023-06-30 Sebastian Aland , Claudia Wohlgemuth

We present a rotationally invariant viscous vertex model that accounts for both cortical and bulk dissipation of cells. The vanishing substrate-friction limit is enforced via Lagrange multipliers, which also provides a framework for…

Biological Physics · Physics 2026-03-31 Shao-Zhen Lin , Sham Tlili , Jean-François Rupprecht
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