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The mitigation of an infectious disease spreading has recently gained considerable attention from the research community. It may be obtained by adopting sanitary measurements social rules, together with an extensive vaccination campaign.…

Social and Information Networks · Computer Science 2022-02-17 Francesco Petrizzelli , Pietro Hiram Guzzi , Tommaso Mazza

We consider the interplay of vaccination and migration rates on disease persistence in epidemiological systems. We show that short-term and long-term migration can inhibit disease persistence. As a result, we show how migration changes how…

Biological Physics · Physics 2012-05-22 Jackson Burton , Lora Billings , Derek A. T. Cummings , Ira B. Schwartz

This article considers the optimal control of the SIR model with both transmission and treatment uncertainty. It follows the model presented in Gatto and Schellhorn (2021). We make four significant improvements on the latter paper. First,…

Optimization and Control · Mathematics 2021-05-20 Yujia Ding , Henry Schellhorn

We devise a theoretical model for the optimal dynamical control of an infectious disease whose diffusion is described by the SVIR compartmental model. The control is realized through implementing social rules to reduce the disease's spread,…

Optimization and Control · Mathematics 2022-08-10 Alessandro Ramponi , Maria Elisabetta Tessitore

We consider the problem of controlling an SIR-model epidemic by temporarily reducing the rate of contact within a population. The control takes the form of a multiplicative reduction in the contact rate of infectious individuals. The…

Optimization and Control · Mathematics 2021-06-29 David I. Ketcheson

We study a game-theoretic model of epidemic control in a large population with finitely many groups and non-cooperative individuals. In the model, individuals jointly choose their socialization levels and vaccination rates, and vaccination…

Optimization and Control · Mathematics 2026-04-28 Huaning Liu , Gokce Dayanikli

Game theory has been an effective tool in the control of disease spread and in suggesting optimal policies at both individual and area levels. In this paper, we propose a multi-region SEIR model based on stochastic differential game theory,…

Optimization and Control · Mathematics 2021-03-10 Yao Xuan , Robert Balkin , Jiequn Han , Ruimeng Hu , Hector D. Ceniceros

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

We present a modified age-structured SIR model based on known patterns of social contact and distancing measures within Washington, USA. We find that population age-distribution has a significant effect on disease spread and mortality rate,…

Populations and Evolution · Quantitative Biology 2022-10-18 Vishaal Ram , Laura P. Schaposnik

In order to explore the impact of periodically evolving domain on the transmission of disease, we study a SIS reaction-diffusion model with logistic term on a periodically evolving domain. The basic reproduction number ${\mathcal{R}}_0$ is…

Analysis of PDEs · Mathematics 2020-11-17 Yachun Tong , Zhigui Lin

Standard epidemiological models for COVID-19 employ variants of compartment (SIR) models at local scales, implicitly assuming spatially uniform local mixing. Here, we examine the effect of employing more geographically detailed diffusion…

The outbreak of mutant strains and vaccination behaviors have been the focus of recent epidemiological research, but most existing epidemic models failed to simultaneously capture viral mutation and consider the complexity and behavioral…

Populations and Evolution · Quantitative Biology 2026-01-16 Wenjie Zhang , Yusheng Li , Qin Li , Guojun Huang , Minyu Feng

The fast transmission rate of COVID-19 worldwide has made this virus the most important challenge of year 2020. Many mitigation policies have been imposed by the governments at different regional levels (country, state, county, and city) to…

Applications · Statistics 2022-05-04 Yue Bai , Abolfazl Safikhani , George Michailidis

In recent years, reinforcement learning and its multi-agent analogue have achieved great success in solving various complex control problems. However, multi-agent reinforcement learning remains challenging both in its theoretical analysis…

Robotics · Computer Science 2023-02-10 Kai Cui , Mengguang Li , Christian Fabian , Heinz Koeppl

The spread of an epidemic is often modeled by an SIR random process on a social network graph. The MinINF problem for optimal social distancing involves minimizing the expected number of infections, when we are allowed to break at most $B$…

Data Structures and Algorithms · Computer Science 2022-02-18 Amy Babay , Michael Dinitz , Aravind Srinivasan , Leonidas Tsepenekas , Anil Vullikanti

A generalization of the standard susceptible-infectious-removed (SIR) stochastic model for epidemics in sparse random networks is introduced which incorporates contact tracing in addition to random screening. We propose a deterministic…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 Ramon Huerta , Lev S. Tsimring

A reaction-diffusion model was developed describing the spread of the COVID-19 virus considering the mean daily movement of susceptible, exposed and asymptomatic individuals. The model was calibrated using data on the confirmed infection…

Populations and Evolution · Quantitative Biology 2020-05-08 Youcef Mammeri

With the continuous rise of the COVID-19 cases worldwide, it is imperative to ensure that all those vulnerable countries lacking vaccine resources can receive sufficient support to contain the risks. COVAX is such an initiative operated by…

Computational Engineering, Finance, and Science · Computer Science 2022-01-20 Navpreet Kaur , Jason Hughes , Juntao Chen

We consider the problem of distributing a vaccine for immunizing a scale-free network against a given virus or worm. We introduce a new method, based on vaccine dissemination, that seems to reflect more accurately what is expected to occur…

Networking and Internet Architecture · Computer Science 2007-05-23 Alexandre O. Stauffer , Valmir C. Barbosa

The ongoing coronavirus disease 2019 (COVID-19) pandemic has wreaked havoc worldwide with millions of lives claimed, human travel restricted and economic development halted. Leveraging city-level mobility and case data, our analysis shows…

Physics and Society · Physics 2022-06-29 Yafei Zhang , Lin Wang , Jonathan J. H. Zhu , Xiaofan Wang