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When applying automatic analysis of fluorescence or histopathological images of cells, it is necessary to partition, or de-clump, partially overlapping cell nuclei. In this work, I describe a method of partitioning partially overlapping…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 James Kapaldo

Nucleus segmentation is a challenging task due to the crowded distribution and blurry boundaries of nuclei. Recent approaches represent nuclei by means of polygons to differentiate between touching and overlapping nuclei and have…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Shengcong Chen , Changxing Ding , Minfeng Liu , Jun Cheng , Dacheng Tao

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

The nematode Caenorhabditis elegans (C. elegans) serves as an important model organism in a wide variety of biological studies. In this paper we introduce a pipeline for automated analysis of C. elegans imagery for the purpose of studying…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Linfeng Wang , Shu Kong , Zachary Pincus , Charless Fowlkes

The graph is one of the most widely used mathematical structures in engineering and science because of its representational power and inherent ability to demonstrate the relationship between objects. The objective of this work is to…

Data Structures and Algorithms · Computer Science 2021-01-01 Shri Prakash Dwivedi

In this paper, we propose a novel hypergraph based method (called HF) to fit and segment multi-structural data. The proposed HF formulates the geometric model fitting problem as a hypergraph partition problem based on a novel hypergraph…

Computer Vision and Pattern Recognition · Computer Science 2016-07-12 Guobao Xiao , Hanzi Wang , Taotao Lai , David Suter

Classifying all cells in an organ is a relevant and difficult problem from plant developmental biology. We here abstract the problem into a new benchmark for node classification in a geo-referenced graph. Solving it requires learning the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-18 Lorenzo Cerrone , Athul Vijayan , Tejasvinee Mody , Kay Schneitz , Fred A. Hamprecht

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Graphs provide a natural way to represent data by encoding information about objects and the relationships between them. With the ever-increasing amount of data collected and generated, locating specific patterns of relationships between…

Data Structures and Algorithms · Computer Science 2026-04-28 Tatyana Benko , Rebecca Jones , Lucas Tate

This research report introduces ElegansNet, a neural network that mimics real-world neuronal network circuitry, with the goal of better understanding the interplay between connectome topology and deep learning systems. The proposed approach…

Neural and Evolutionary Computing · Computer Science 2024-04-01 Francesco Bardozzo , Andrea Terlizzi , Pietro Liò , Roberto Tagliaferri

In this paper, we propose a simple and effective {geometric} model fitting method to fit and segment multi-structure data even in the presence of severe outliers. We cast the task of geometric model fitting as a representative mode-seeking…

Computer Vision and Pattern Recognition · Computer Science 2018-02-07 Hanzi Wang , Guobao Xiao , Yan Yan , David Suter

Background: Single-particle cryo-electron microscopy (cryo-EM) has become a popular tool for structural determination of biological macromolecular complexes. High-resolution cryo-EM reconstruction often requires hundreds of thousands of…

Data Analysis, Statistics and Probability · Physics 2017-09-05 Yanan Zhu , Qi Ouyang , Youdong Mao

This study introduces an artificial neural network (ANN) for image classification task, inspired by the aversive olfactory learning circuits of the nematode Caenorhabditis elegans (C. elegans). Despite the remarkable performance of ANNs in…

Neural and Evolutionary Computing · Computer Science 2024-09-13 Xuebin Wang , Chunxiuzi Liu , Meng Zhao , Ke Zhang , Zengru Di , He Liu

Automated detection of cervical cancer cells or cell clumps has the potential to significantly reduce error rate and increase productivity in cervical cancer screening. However, most traditional methods rely on the success of accurate cell…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Yixiong Liang , Zhihong Tang , Meng Yan , Jialin Chen , Qing Liu , Yao Xiang

Template matching by normalized cross correlation (NCC) is widely used for finding image correspondences. We improve the robustness of this algorithm by preprocessing images with "siamese" convolutional networks trained to maximize the…

Computer Vision and Pattern Recognition · Computer Science 2017-05-25 Davit Buniatyan , Thomas Macrina , Dodam Ih , Jonathan Zung , H. Sebastian Seung

The graph matching optimization problem is an essential component for many tasks in computer vision, such as bringing two deformable objects in correspondence. Naturally, a wide range of applicable algorithms have been proposed in the last…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Stefan Haller , Lorenz Feineis , Lisa Hutschenreiter , Florian Bernard , Carsten Rother , Dagmar Kainmüller , Paul Swoboda , Bogdan Savchynskyy

Modern histopathological image analysis relies on the segmentation of cell structures to derive quantitative metrics required in biomedical research and clinical diagnostics. State-of-the-art deep learning approaches predominantly apply…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Yoav Alon , Huiyu Zhou

Cancer is a leading cause of death worldwide, necessitating advancements in early detection and treatment technologies. In this paper, we present a novel and highly efficient melanoma detection framework that synergistically combines the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Peng Zhang , Divya Chaudhary

Deep neural networks trained for classification have been found to learn powerful image representations, which are also often used for other tasks such as comparing images w.r.t. their visual similarity. However, visual similarity does not…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Björn Barz , Joachim Denzler