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Computer-aided analysis of biological microscopy data has seen a massive improvement with the utilization of general-purpose deep learning techniques. Yet, in microscopy studies of multi-organism systems, the problem of collision and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Albert Alonso , Julius B. Kirkegaard

Caenorhabditis elegans (C. elegans) is an excellent model organism because of its short lifespan and high degree of homology with human genes, and it has been widely used in a variety of human health and disease models. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Mengqian Dinga , Jun Liua , Yang Luo , Jinshan Tang

Hypergraphs are generalisation of graphs in which a hyperedge can connect any number of vertices. It can describe n-ary relationships and high-order information among entities compared to conventional graphs. In this paper, we study the…

Databases · Computer Science 2023-02-21 Zhengyi Yang , Wenjie Zhang , Xuemin Lin , Ying Zhang , Shunyang Li

Medical images like CT and MRI provide detailed information about the internal structure of the body, and identifying key anatomical structures from these images plays a crucial role in clinical workflows. Current methods treat it as a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xiaoyu Bai , Yong Xia

Graph matching problem aims to identify node correspondence between two or more correlated graphs. Previous studies have primarily focused on models where only edge information is provided. However, in many social networks, not only the…

Information Theory · Computer Science 2024-07-18 Joonhyuk Yang , Hye Won Chung

Cellular Electron CryoTomography (CECT) is a 3D imaging technique that captures information about the structure and spatial organization of macromolecular complexes within single cells, in near-native state and at sub-molecular resolution.…

Quantitative Methods · Quantitative Biology 2018-07-04 Kai Wen Wang , Xiangrui Zeng , Xiaodan Liang , Zhiguang Huo , Eric P. Xing , Min Xu

Accurate and reliable nuclei identification is an essential part of quantification in microscopy. A range of mathematical and machine learning approaches are used but all methods have limitations. Such limitations include sensitivity to…

Quantitative Methods · Quantitative Biology 2019-04-11 Carl J. Nelson , Philip T. G. Jackson , Boguslaw Obara

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Despite recent interest in reconstructing neuronal networks, complete wiring diagrams on the level of individual synapses remain scarce and the insights into function they can provide remain unclear. Even for Caenorhabditis elegans, whose…

Neurons and Cognition · Quantitative Biology 2011-02-07 Lav R. Varshney , Beth L. Chen , Eric Paniagua , David H. Hall , Dmitri B. Chklovskii

Is matching in NC, i.e., is there a deterministic fast parallel algorithm for it? This has been an outstanding open question in TCS for over three decades, ever since the discovery of randomized NC matching algorithms [KUW85, MVV87]. Over…

Data Structures and Algorithms · Computer Science 2020-11-10 Nima Anari , Vijay V. Vazirani

Symmetries found through automorphisms or graph fibrations provide important insights in network analysis. Symmetries identify clusters of robust synchronization in the network which improves the understanding of the functionality of…

Quantitative Methods · Quantitative Biology 2022-07-27 Ian Leifer , David Phillips , Francesco Sorrentino , Hernán A. Makse

Automatic detection of abnormal cervical cells from Thinprep Cytologic Test (TCT) images is a critical component in the development of intelligent computer-aided diagnostic systems. However, existing algorithms typically fail to effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Jincheng Li , Danyang Dong , Menglin Zheng , Jingbo Zhang , Yueqin Hang , Lichi Zhang , Lili Zhao

Complex networks can be used to analyze structures and systems in the embryo. Not only can we characterize growth and the emergence of form, but also differentiation. The process of differentiation from precursor cell populations to…

Quantitative Methods · Quantitative Biology 2023-11-30 Bradly Alicea

3D cell tracking in a living organism has a crucial role in live cell image analysis. Cell tracking in C. elegans has two difficulties. First, cell migration in a consecutive frame is large since they move their head during scanning.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Kaito Shiku , Hiromitsu Shirai , Takeshi Ishihara , Ryoma Bise

Finding dense substructures in a graph is a fundamental graph mining operation, with applications in bioinformatics, social networks, and visualization to name a few. Yet most standard formulations of this problem (like clique, quasiclique,…

Social and Information Networks · Computer Science 2015-03-10 Ahmet Erdem Sariyuce , C. Seshadhri , Ali Pinar , Umit V. Catalyurek

Entity alignment is crucial for merging knowledge across knowledge graphs, as it matches entities with identical semantics. The standard method matches these entities based on their embedding similarities using semi-supervised learning.…

Computation and Language · Computer Science 2024-10-29 Wei Ai , Yinghui Gao , Jianbin Li , Jiayi Du , Tao Meng , Yuntao Shou , Keqin Li

Is perfect matching in NC? That is, is there a deterministic fast parallel algorithm for it? This has been an outstanding open question in theoretical computer science for over three decades, ever since the discovery of RNC matching…

Data Structures and Algorithms · Computer Science 2018-04-24 Nima Anari , Vijay V. Vazirani

Many problems such as node classification and link prediction in network data can be solved using graph embeddings. However, it is difficult to use graphs to capture non-binary relations such as communities of nodes. These kinds of complex…

Social and Information Networks · Computer Science 2022-01-27 Sepideh Maleki , Donya Saless , Dennis P. Wall , Keshav Pingali

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Satoshi Kondo , Satoshi Kasai

We consider the algorithmic decision problem that takes as input an $n$-vertex $k$-uniform hypergraph $H$ with minimum codegree at least $m-c$ and decides whether it has a matching of size $m$. We show that this decision problem is fixed…

Combinatorics · Mathematics 2022-10-25 Jie Han , Peter Keevash