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Tokenization is a promising path to multi-modal models capable of jointly understanding protein sequences, structure, and function. Existing protein structure tokenizers create tokens by pooling information from local neighborhoods, an…

Machine Learning · Computer Science 2026-02-09 Rohit Dilip , Ayush Varshney , David Van Valen

We present a rapid stellar core-collapse waveform emulator built using a deep convolutional generative adversarial network (DCGAN). The DCGAN was trained on the Richers \textit{et al.~}\cite{richers:2017} waveform catalogue to learn the…

General Relativity and Quantum Cosmology · Physics 2024-11-28 Tarin Eccleston , Matthew C. Edwards

Deep generative models are known to be able to model arbitrary probability distributions. Among these, a recent deep generative model, dubbed sliceGAN, proposed a new way of using the generative adversarial network (GAN) to capture the…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Hyungjin Chung , Jong Chul Ye

Proteins are essential components of all living organisms and play a critical role in cellular survival. They have a broad range of applications, from clinical treatments to material engineering. This versatility has spurred the development…

Applications · Statistics 2025-03-28 Chenyu Ren , Daihai He , Jian Huang

We consider the problem of modelling high-dimensional distributions and generating new examples of data with complex relational feature structure coherent with a graph skeleton. The model we propose tackles the problem of generating the…

Machine Learning · Computer Science 2022-12-02 Yoann Boget , Magda Gregorova , Alexandros Kalousis

The structure of a protein is crucial in determining its functionality, and is much more conserved than sequence during evolution. A key task in structural biology is to compare protein structures in order to determine evolutionary…

Methodology · Statistics 2019-11-06 Christopher Fallaize , Peter Green , Kanti Mardia , Stuart Barber

In this paper we address the problem of protein classification starting from a multi-view 2D representation of proteins. From each 3D protein structure, a large set of 2D projections is generated using the protein visualization software…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Loris Nanni , Alessandra Lumini , Federica Pasquali , Sheryl Brahnam

Convolutional neural networks (CNNs) have been combined with generative adversarial networks (GANs) to create deep convolutional generative adversarial networks (DCGANs) with great success. DCGANs have been used for generating images and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Sebastian Hereu , Qianfei Hu

Image composition is a complex task which requires a lot of information about the scene for an accurate and realistic composition, such as perspective, lighting, shadows, occlusions, and object interactions. Previous methods have…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Amr Ghoneim , Jiju Poovvancheri , Yasushi Akiyama , Dong Chen

Proteins power a vast array of functional processes in living cells. The capability to create new proteins with designed structures and functions would thus enable the engineering of cellular behavior and development of protein-based…

Biomolecules · Quantitative Biology 2023-06-08 Yeqing Lin , Mohammed AlQuraishi

We focus on graph-to-sequence learning, which can be framed as transducing graph structures to sequences for text generation. To capture structural information associated with graphs, we investigate the problem of encoding graphs using…

Computation and Language · Computer Science 2019-09-10 Zhijiang Guo , Yan Zhang , Zhiyang Teng , Wei Lu

A novel approach for structure alignment is presented, where the key ingredients are: (1) An error function formulation of the problem simultaneously in terms of binary (Potts) assignment variables and real-valued atomic coordinates. (2)…

Biological Physics · Physics 2007-05-23 M. Ohlsson , C. Peterson , M. Ringner , R. Blankenbecler

Learning and reasoning about 3D molecular structures with varying size is an emerging and important challenge in machine learning and especially in drug discovery. Equivariant Graph Neural Networks (GNNs) can simultaneously leverage the…

Machine Learning · Computer Science 2022-03-03 Tuan Le , Frank Noé , Djork-Arné Clevert

X-ray tomography is capable of imaging the interior of objects in three dimensions non-invasively, with applications in biomedical imaging, materials science, electronic inspection, and other fields. The reconstruction process can be an…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Zhen Guo , Jung Ki Song , George Barbastathis , Michael E. Glinsky , Courtenay T. Vaughan , Kurt W. Larson , Bradley K. Alpert , Zachary H. Levine

Generating images via the generative adversarial network (GAN) has attracted much attention recently. However, most of the existing GAN-based methods can only produce low-resolution images of limited quality. Directly generating…

Computer Vision and Pattern Recognition · Computer Science 2019-04-01 Yong Guo , Qi Chen , Jian Chen , Qingyao Wu , Qinfeng Shi , Mingkui Tan

In this paper, we present InSeGAN, an unsupervised 3D generative adversarial network (GAN) for segmenting (nearly) identical instances of rigid objects in depth images. Using an analysis-by-synthesis approach, we design a novel GAN…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Anoop Cherian , Goncalo Dias Pais , Siddarth Jain , Tim K. Marks , Alan Sullivan

Tremendous progress has been witnessed in artificial intelligence where neural network backed deep learning systems have been used, with applications in almost every domain. As a representative deep learning framework, Generative…

Quantum Physics · Physics 2022-09-26 Samuel A. Stein , Betis Baheri , Daniel Chen , Ying Mao , Qiang Guan , Ang Li , Bo Fang , Shuai Xu

Biological systems can be studied at multiple levels of information, including gene, protein, RNA and different interaction networks levels. The goal of this work is to explore how the fusion of systems' level information with temporal…

Genomics · Quantitative Biology 2023-02-09 Jan Kralj , Blaž Škrlj , Živa Ramšak , Nada Lavrač , Kristina Gruden

High-throughput screening has become one of the major strategies for the discovery of novel functional materials. However, its effectiveness is severely limited by the lack of quantity and diversity of known materials deposited in the…

Generative Adversarial Networks (GANs) have been very successful for synthesizing the images in a given dataset. The artificially generated images by GANs are very realistic. The GANs have shown potential usability in several computer…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Shiv Ram Dubey , Satish Kumar Singh