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Functional groups (FGs) are molecular substructures that are served as a foundation for analyzing and predicting chemical properties of molecules. Automatic discovery of FGs will impact various fields of research, including medicinal…

Machine Learning · Computer Science 2019-10-11 Phillip Pope , Soheil Kolouri , Mohammad Rostrami , Charles Martin , Heiko Hoffmann

Intricate comparison between two given tertiary structures of proteins is as important as the comparison of their functions. Several algorithms have been devised to compute the similarity and dissimilarity among protein structures. But,…

Computational Geometry · Computer Science 2013-09-26 Ranjeet Kumar Rout , Pabitra Pal Choudhury , B. S. Daya Sagar , Sk. Sarif Hassan

With widely deployed WiFi network and the uniqueness feature (fingerprint) of wireless channel information, fingerprinting based WiFi positioning is currently the mainstream indoor positioning method, in which fingerprint database…

Networking and Internet Architecture · Computer Science 2019-10-14 Qiyue Li , Heng Qu , Zhi Liu , Nana Zhou , Wei Sun , Stephan Sigg , Jie Li

Introduction Accurate prediction of protein-protein interactions (PPIs) is crucial for understanding cellular functions and advancing drug development. Existing in-silico methods use direct sequence embeddings from Protein Language Models…

Machine Learning · Computer Science 2025-10-17 Islam Akef Ebeid , Haoteng Tang , Pengfei Gu

The convolutional neural network (CNN), which is one of the deep learning models, has seen much success in a variety of computer vision tasks. However, designing CNN architectures still requires expert knowledge and a lot of trial and…

Neural and Evolutionary Computing · Computer Science 2017-08-14 Masanori Suganuma , Shinichi Shirakawa , Tomoharu Nagao

Motivation Protein fold recognition is an important problem in structural bioinformatics. Almost all traditional fold recognition methods use sequence (homology) comparison to indirectly predict the fold of a tar get protein based on the…

Machine Learning · Computer Science 2017-06-06 Jie Hou , Badri Adhikari , Jianlin Cheng

Fine-grained image search is still a challenging problem due to the difficulty in capturing subtle differences regardless of pose variations of objects from fine-grained categories. In practice, a dynamic inventory with new fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2018-07-09 Kevin Lin , Fan Yang , Qiaosong Wang , Robinson Piramuthu

This paper presents new designs of graph convolutional neural networks (GCNs) on 3D meshes for 3D object segmentation and classification. We use the faces of the mesh as basic processing units and represent a 3D mesh as a graph where each…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Wenming Tang Guoping Qiu

Molecular structure-property relationships are key to molecular engineering for materials and drug discovery. The rise of deep learning offers a new viable solution to elucidate the structure-property relationships directly from chemical…

Machine Learning · Computer Science 2018-10-09 Seongok Ryu , Jaechang Lim , Seung Hwan Hong , Woo Youn Kim

We introduce PathGAN, a deep neural network for visual scanpath prediction trained on adversarial examples. A visual scanpath is defined as the sequence of fixation points over an image defined by a human observer with its gaze. PathGAN is…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Marc Assens , Xavier Giro-i-Nieto , Kevin McGuinness , Noel E. O'Connor

Local protein structure analysis is informative to protein structure analysis and has been used successfully in protein structure prediction and others. Proteins have recurring structural features, such as helix caps and beta turns, which…

Combinatorics · Mathematics 2007-10-26 Naoto Morikawa

The prosperity of computer vision (CV) and natural language procession (NLP) in recent years has spurred the development of deep learning in many other domains. The advancement in machine learning provides us with an alternative option…

Machine Learning · Computer Science 2020-12-02 Chen Qian , Yunhai Xiong , Xiang Chen

Generative modeling has become a central paradigm in protein research, extending machine learning beyond structure prediction toward sequence design, backbone generation, inverse folding, and biomolecular interaction modeling. However, the…

Machine Learning · Computer Science 2026-03-30 Senura Hansaja Wanasekara , Minh-Duong Nguyen , Xiaochen Liu , Nguyen H. Tran , Ken-Tye Yong

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

Quantitative Methods · Quantitative Biology 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

Motivation: Thanks to the recent advances in structural biology, nowadays three-dimensional structures of various proteins are solved on a routine basis. A large portion of these contain structural repetitions or internal symmetries. To…

Quantitative Methods · Quantitative Biology 2018-10-30 Guillaume Pagès , Sergei Grudinin

Digital reconstruction of porous materials has become increasingly critical for applications ranging from geological reservoir characterization to tissue engineering and electrochemical device design. While traditional methods such as…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ali Sadeghkhani , Brandon Bennett , Masoud Babaei , Arash Rabbani

Proteins are the basic building blocks of life. They usually perform functions by folding to a particular structure. Understanding the folding process could help the researchers to understand the functions of proteins and could also help to…

Computational Engineering, Finance, and Science · Computer Science 2015-10-21 Jianzhu Ma

Facial recognition using deep convolutional neural networks relies on the availability of large datasets of face images. Many examples of identities are needed, and for each identity, a large variety of images are needed in order for the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Richard T. Marriott , Sami Romdhani , Liming Chen

Deep learning is catalyzing a scientific revolution fueled by big data, accessible toolkits, and powerful computational resources, impacting many fields including protein structural modeling. Protein structural modeling, such as predicting…

Biomolecules · Quantitative Biology 2020-07-17 Wenhao Gao , Sai Pooja Mahajan , Jeremias Sulam , Jeffrey J. Gray

The deep generative adversarial networks (GAN) recently have been shown to be promising for different computer vision applications, like image edit- ing, synthesizing high resolution images, generating videos, etc. These networks and the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-18 Ali Diba , Vivek Sharma , Rainer Stiefelhagen , Luc Van Gool