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The Robertson model describing a chemical reaction involving three reactants is one of the classical examples of stiffness in ODEs. The stiffness is caused by the occurrence of three reaction rates $k_1,\,k_2$, and $k_3$, with largely…

Dynamical Systems · Mathematics 2025-02-07 Lukas Baumgartner , Peter Szmolyan

We analyze a class of cell-bulk coupled PDE-ODE models, motivated by quorum and diffusion sensing phenomena in microbial systems, that characterize communication between localized spatially segregated dynamically active signaling…

Pattern Formation and Solitons · Physics 2020-07-20 Sarafa A. Iyaniwura , Michael J. Ward

Ordinary differential equations (ODEs) can provide mechanistic models of temporally local changes of processes, where parameters are often informed by external knowledge. While ODEs are popular in systems modeling, they are less established…

Methodology · Statistics 2025-07-10 Maren Hackenberg , Astrid Pechmann , Clemens Kreutz , Janbernd Kirschner , Harald Binder

Molecular simulations as well as single molecule experiments have been widely analyzed in terms order parameters, the latter representing candidate probes for the relevant degrees of freedom. Notwithstanding this approach is very intuitive,…

Chemical Physics · Physics 2015-06-11 Ganna Berezovska , Diego Prada-Gracia , Stefano Mostarda , Francesco Rao

Many physical systems are governed by ordinary or partial differential equations (see, for example, Chapter ''Differential equations'', ''System of Differential Equations''). Typically the solution of such systems are functions of time or…

Numerical Analysis · Mathematics 2023-09-06 Clarissa Astuto , Giovanni Russo

This paper investigates the stability and stabilization of semilinear single-track vehicle models with distributed tire friction dynamics, modeled as interconnections of ordinary differential equations (ODEs) and hyperbolic partial…

Systems and Control · Electrical Eng. & Systems 2026-02-10 Luigi Romano , Ole Morten Aamo , Miroslav Krstić , Jan Åslund , Erik Frisk

We present a parameter estimation method in Ordinary Differential Equation (ODE) models. Due to complex relationships between parameters and states the use of standard techniques such as nonlinear least squares can lead to the presence of…

Methodology · Statistics 2018-10-11 Quentin Clairon

The neural ordinary differential equation (ODE) framework has emerged as a powerful tool for developing accelerated surrogate models of complex physical systems governed by partial differential equations (PDEs). A popular approach for PDE…

Fluid Dynamics · Physics 2025-03-26 Ashish S. Nair , Shivam Barwey , Pinaki Pal , Jonathan F. MacArt , Troy Arcomano , Romit Maulik

Traditionally, calcium dynamics in neurons are modeled using partial differential equations (PDEs) and ordinary differential equations (ODEs). The PDE component focuses on reaction-diffusion processes, while the ODE component addresses…

Numerical Analysis · Mathematics 2024-07-23 Abel Gurung , Qingguang Guan

Biological systems are non-linear, include unobserved variables and the physical principles that govern their dynamics are partly unknown. This makes the characterization of their behavior very challenging. Notably, their activity occurs on…

Quantitative Methods · Quantitative Biology 2025-06-27 Andréa Ducos , Audrey Denizot , Thomas Guyet , Hugues Berry

Statistical regression models whose mean functions are represented by ordinary differential equations (ODEs) can be used to describe phenomenons dynamical in nature, which are abundant in areas such as biology, climatology and genetics. The…

Methodology · Statistics 2017-05-15 Kyoungjae Lee , Jaeyong Lee , Sarat C. Dass

Oscillations of free intracellular calcium concentration are thought to be important in the control of a wide variety of physiological phenomena, and there is long-standing interest in understanding these oscillations via the investigation…

Dynamical Systems · Mathematics 2024-01-31 Behnaz Rahmani , Samuel Jelbart , Vivien Kirk , James Sneyd

The paper gives a systematic analysis of singularities of transition processes in dynamical systems. General dynamical systems with dependence on parameter are studied. A system of relaxation times is constructed. Each relaxation time…

chao-dyn · Physics 2009-01-28 A. N. Gorban

Second-order phase transitions are characterised by critical scaling and universality. The singular behaviour of thermodynamic quantities at the transition, in particular, is determined by critical exponents of the universality class of the…

Ordinary Differential Equations are widespread tools to model chemical, physical, biological process but they usually rely on parameters which are of critical importance in terms of dynamic and need to be estimated directly from the data.…

Methodology · Statistics 2014-10-29 Nicolas Brunel , Quentin Clairon

In this paper we study analytically a parameter switching (PS) algorithm applied to a class of systems of ODE, depending on a single real parameter. The algorithm allows the numerical approximation of any solution of the underlying system…

Chaotic Dynamics · Physics 2016-07-12 Marius-F. Danca , Michal Feckan

We study the long-term qualitative behavior of randomly perturbed dynamical systems. More specifically, we look at limit cycles of stochastic differential equations (SDE) with Markovian switching, in which the process switches at random…

Probability · Mathematics 2024-07-10 Nguyen H. Du , Alexandru Hening , Dang H. Nguyen , George Yin

Ordinary differential equation (ODE) models of gradient-based optimization methods can provide insights into the dynamics of learning and inspire the design of new algorithms. Unfortunately, this thought-provoking perspective is weakened by…

Optimization and Control · Mathematics 2019-11-14 Antonio Orvieto , Aurelien Lucchi

$Circuit~ Complexity$, a well known computational technique has recently become the backbone of the physics community to probe the chaotic behaviour and random quantum fluctuations of quantum fields. This paper is devoted to the study of…

Most of the calcium in the body is stored in bone. The rest is stored elsewhere, and calcium signalling is one of the most important mechanisms of information propagation in the body. Yet, many questions remain open. In this work, we…

Dynamical Systems · Mathematics 2017-03-03 Katerina Kaouri , Philip K. Maini , S. Jonathan Chapman
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