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Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

Individual's general well-being is greatly impacted by mental health conditions including depression and Post-Traumatic Stress Disorder (PTSD), underscoring the importance of early detection and precise diagnosis in order to facilitate…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

Human-Computer Interaction · Computer Science 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Neuro-developmental disorders are manifested as dysfunctions in cognition, communication, behaviour and adaptability, and deep learning-based computer-aided diagnosis (CAD) can alleviate the increasingly strained healthcare resources on…

Machine Learning · Computer Science 2026-04-17 Xin Wen , Shijie Guo , Wenbo Ning , Rui Cao , Jie Xiang , Xiaobo Liu , Jintai Chen

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

Machine Learning · Computer Science 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

{Introduction: } Dementia is a neurological disorder associated with aging that can cause a loss of cognitive functions, impacting daily life. Alzheimer's disease (AD) is the most common cause of dementia, accounting for 50--70\% of cases,…

Neurons and Cognition · Quantitative Biology 2023-11-07 Zaineb Ajra , Binbin Xu , Gérard Dray , Jacky Montmain , Stéphane Perrey

Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…

Computation and Language · Computer Science 2025-06-12 Yao Xiao , Heidi Christensen , Stefan Goetze

Autism Spectrum Disorder (ASD) is a severe neuropsychiatric disorder that affects intellectual development, social behavior, and facial features, and the number of cases is still significantly increasing. Due to the variety of symptoms ASD…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Ryan Liu , Spencer He

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Dementia is a growing problem as our society ages, and detection methods are often invasive and expensive. Recent deep-learning techniques can offer a faster diagnosis and have shown promising results. However, they require large amounts of…

Computation and Language · Computer Science 2022-07-19 Anna Hlédiková , Dominika Woszczyk , Alican Akman , Soteris Demetriou , Björn Schuller

The aging population of the U.S. drives the prevalence of Alzheimer's disease. Brookmeyer et al. forecasts approximately 15 million Americans will have either clinical AD or mild cognitive impairment by 2060. In response to this urgent…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Long Chen , Liben Chen , Binfeng Xu , Wenxin Zhang , Narges Razavian

The ageing population trend is correlated with an increased prevalence of acquired cognitive impairments such as dementia. Although there is no cure for dementia, a timely diagnosis helps in obtaining necessary support and appropriate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-06 Xing Liang , Anastassia Angelopoulou , Epaminondas Kapetanios , Bencie Woll , Reda Al-batat , Tyron Woolfe

Following the recent development of quantum machine learning techniques, the literature has reported several quantum machine learning algorithms for disease detection. This study explores the application of a hybrid quantum-classical…

Machine Learning · Computer Science 2024-05-06 Junggu Choi , Tak Hur , Daniel K. Park , Na-Young Shin , Seung-Koo Lee , Hakbae Lee , Sanghoon Han

Early detection of dementia through specific biomarkers in MR images plays a critical role in developing support strategies proactively. Fazekas scale facilitates an accurate quantitative assessment of the severity of white matter lesions…

Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD,…

Quantitative Methods · Quantitative Biology 2025-01-27 Roberto Goya-Maldonado , Tracy Erwin-Grabner , Ling-Li Zeng , Christopher R. K. Ching , Andre Aleman , Alyssa R. Amod , Zeynep Basgoze , Francesco Benedetti , Bianca Besteher , Katharina Brosch , Robin Bülow , Romain Colle , Colm G. Connolly , Emmanuelle Corruble , Baptiste Couvy-Duchesne , Kathryn Cullen , Udo Dannlowski , Christopher G. Davey , Annemiek Dols , Jan Ernsting , Jennifer W. Evans , Lukas Fisch , Paola Fuentes-Claramonte , Ali Saffet Gonul , Ian H. Gotlib , Hans J. Grabe , Nynke A. Groenewold , Dominik Grotegerd , Tim Hahn , J. Paul Hamilton , Laura K. M. Han , Ben J. Harrison , Tiffany C. Ho , Neda Jahanshad , Alec J. Jamieson , Andriana Karuk , Tilo Kircher , Bonnie Klimes-Dougan , Sheri-Michelle Koopowitz , Thomas Lancaster , Ramona Leenings , Meng Li , David E. J. Linden , Frank P. MacMaster , David M. A. Mehler , Susanne Meinert , Elisa Melloni , Bryon A. Mueller , Benson Mwangi , Igor Nenadić , Amar Ojha , Yasumasa Okamoto , Mardien L. Oudega , Brenda W. J. H. Penninx , Sara Poletti , Edith Pomarol-Clotet , Maria J. Portella , Elena Pozzi , Joaquim Radua , Elena Rodríguez-Cano , Matthew D. Sacchet , Raymond Salvador , Anouk Schrantee , Kang Sim , Jair C. Soares , Aleix Solanes , Dan J. Stein , Frederike Stein , Aleks Stolicyn , Sophia I. Thomopoulos , Yara J. Toenders , Aslihan Uyar-Demir , Eduard Vieta , Yolanda Vives-Gilabert , Henry Völzke , Martin Walter , Heather C. Whalley , Sarah Whittle , Nils Winter , Katharina Wittfeld , Margaret J. Wright , Mon-Ju Wu , Tony T. Yang , Carlos Zarate , Dick J. Veltman , Lianne Schmaal , Paul M. Thompson

Dementia and especially Alzheimer's disease (AD) are the most common causes of cognitive decline in elderly people. A spread of the above mentioned mental health problems in aging societies is causing a significant medical and economic…

Neurons and Cognition · Quantitative Biology 2018-12-03 Tomasz M. Rutkowski , Qibin Zhao , Masao S. Abe , Mihoko Otake

Age-related Macular Degeneration (AMD) is a leading cause of blindness. Although the Age-Related Eye Disease Study group previously developed a 9-step AMD severity scale for manual classification of AMD severity from color fundus images,…

Machine Learning · Computer Science 2018-12-04 Qingyu Chen , Yifan Peng , Tiarnan Keenan , Shazia Dharssi , Elvira Agron , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

The main objective of this paper is to propose an approach for developing an Artificial Intelligence (AI)-powered Language Assessment (LA) tool. Such tools can be used to assess language impairments associated with dementia in older adults.…

Computation and Language · Computer Science 2022-09-27 Mahboobeh Parsapoor , Muhammad Raisul Alam , Alex Mihailidis

This paper applies a hidden Markov model to the problem of Attention Deficit Hyperactivity Disorder (ADHD) diagnosis from resting-state functional Magnetic Resonance Image (fMRI) scans of subjects. The proposed model considers the temporal…

Quantitative Methods · Quantitative Biology 2015-06-22 Bhaskar Sen , Zheng Shi , Gregory Burlet
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