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Purpose: Immunotherapies have revolutionized the landscape of cancer treatments. However, our understanding of response patterns in advanced cancers treated with immunotherapy remains limited. By leveraging routinely collected noninvasive…
Functional Magnetic Resonance Imaging (fMRI) captures the temporal dynamics of neural activity as a function of spatial location in the brain. Thus, fMRI scans are represented as 4-Dimensional (3-space + 1-time) tensors. And it is widely…
Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…
Dementia is a complex syndrome impacting cognitive and emotional functions, with Alzheimer's disease being the most common form. This study focuses on enhancing dementia prediction using machine learning (ML) techniques on patient health…
The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…
Dementia is a syndrome, generally of a chronic nature characterized by a deterioration in cognitive function, especially in the geriatric population and is severe enough to impact their daily activities. Early diagnosis of dementia is…
Dementia is a neurodegenerative disorder that has been growing among elder people over the past decades. This growth profoundly impacts the quality of life for patients and caregivers due to the symptoms arising from it. Agitation and…
Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…
Accurate automatic classification of major tissue classes and the cerebrospinal fluid in pediatric MR scans of early childhood brains remains a challenge. A poor and highly variable grey matter and white matter contrast on T1-weighted MR…
Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…
Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…
Alzheimer's disease (AD) is the most common cause of dementia. An early detection is crucial for slowing down the disease and mitigating risks related to the progression. While the combination of MRI and FDG-PET is the best image-based tool…
Purpose: Thyroid scintigraphy plays a vital role in diagnosing a range of thyroid disorders. While deep learning classification models hold significant promise in this domain, their effectiveness is frequently compromised by limited and…
Alzheimer's disease and related dementias(ADRD) affect nearly five million older adults in the United States, yet more than half remain undiagnosed. Speech-based natural language processing(NLP) offers a scalable approach for detecting…
Objective: Assessing Alzheimer's disease (AD) using high-dimensional radiology images is clinically important but challenging. Although Artificial Intelligence (AI) has advanced AD diagnosis, it remains unclear how to design AI models…
Algorithmic detection of facial palsy offers the potential to improve current practices, which usually involve labor-intensive and subjective assessment by clinicians. In this paper, we present a multimodal fusion-based deep learning model…
Early diagnosis and intervention for Autism Spectrum Disorder (ASD) has been shown to significantly improve the quality of life of autistic individuals. However, diagnostics methods for ASD rely on assessments based on clinical presentation…
Accurate and efficient classification of Alzheimer's disease (AD) severity from brain magnetic resonance imaging (MRI) remains a critical challenge, particularly when limited data and model interpretability are of concern. In this work, we…
Dementia disorders are increasingly becoming sources of a broad range of problems, strongly interfering with normal daily tasks of a growing number of individuals. Such neurodegenerative diseases are often accompanied with progressive brain…
Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…