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The topic of this paper is prevalence estimation from the perspective of active information. Prevalence among tested individuals has an upward bias under the assumption that individuals' willingness to be tested for the disease increases…

Methodology · Statistics 2022-06-13 Ola Hössjer , Daniel Andrés Díaz-Pachón , Chen Zhao , J. Sunil Rao

Membership Inference attacks (MIAs) aim to predict whether a data sample was present in the training data of a machine learning model or not, and are widely used for assessing the privacy risks of language models. Most existing attacks rely…

Computation and Language · Computer Science 2023-08-08 Justus Mattern , Fatemehsadat Mireshghallah , Zhijing Jin , Bernhard Schölkopf , Mrinmaya Sachan , Taylor Berg-Kirkpatrick

Infectious disease modeling and forecasting have played a key role in helping assess and respond to epidemics and pandemics. Recent work has leveraged data on disease peak infection and peak hospital incidence to fit compartmental models…

We introduce a new version of forward stepwise regression. Our modification finds solutions to regression problems where the selected predictors appear in a structured pattern, with respect to a predefined distance measure over the…

Methodology · Statistics 2011-08-02 Daniel Percival , Kathryn Roeder , Roni Rosenfeld , Larry Wasserman

Strategic test allocation plays a major role in the control of both emerging and existing pandemics (e.g., COVID-19, HIV). Widespread testing supports effective epidemic control by (1) reducing transmission via identifying cases, and (2)…

Methodology · Statistics 2022-12-06 Ivana Malenica , Jeremy R. Coyle , Mark J. van der Laan , Maya L. Petersen

Due to the widespread availability of effective antiretroviral therapy (ART) regimens, average lifespans of persons with HIV (PWH) in the United States have increased significantly in recent decades. In turn, the demographic profile of PWH…

Dynamical Systems · Mathematics 2025-03-21 Alex Viguerie , Elisa Iacomini

We will study a mathematical model of the human immunodeficiency virus (HIV) infection in the presence of combination therapy that includes within-host infectious dynamics. The deterministic model requires us to analyze asymptotic stability…

Populations and Evolution · Quantitative Biology 2017-09-04 Majid Jaberi Douraki

Early in an infectious disease outbreak, timely and accurate estimation of the basic reproduction number ($R_0$) and the serial interval (SI) is critical for understanding transmission dynamics and informing public health responses. While…

Methodology · Statistics 2026-01-29 Tatiana Krikella , Jane M. Heffernan , Hanna Jankowski

To make informative public policy decisions in battling the ongoing COVID-19 pandemic, it is important to know the disease prevalence in a population. There are two intertwined difficulties in estimating this prevalence based on testing…

Methodology · Statistics 2020-12-01 Bryan Cai , John P. A. Ioannidis , Eran Bendavid , Lu Tian

Contact-tracing is an essential tool in order to mitigate the impact of pandemic such as the COVID-19. In order to achieve efficient and scalable contact-tracing in real time, digital devices can play an important role. While a lot of…

In this paper, we continue development of the new epidemiological model HIT, which is suitable for analyzing and predicting the propagation of COVID-19 epidemics. This is a discrete-time model allowing a reconstruction of the dynamics of…

Physics and Society · Physics 2020-07-24 Yurii Nesterov

Interval-censored competing risks data arise when each study subject may experience an event or failure from one of several causes and the failure time is not observed exactly but rather known to lie in an interval between two successive…

Methodology · Statistics 2016-03-02 Lu Mao , D. Y. Lin , Donglin Zeng

We introduce a new method for inference in stochastic epidemic models which uses recursive multinomial approximations to integrate over unobserved variables and thus circumvent likelihood intractability. The method is applicable to a class…

Methodology · Statistics 2021-02-24 Nick Whiteley , Lorenzo Rimella

In this work, we present two defective regression models for the analysis of interval-censored competing risk data in the presence of cured individuals, viz., defective Gompertz and defective inverse Gaussian regression models. The proposed…

Methodology · Statistics 2024-12-09 Silpa K. , Sreedevi E. P. , P. G. Sankaran

Safe and effective preventive vaccines have the potential to help stem the HIV epidemic. The efficacy of such vaccines is typically measured in randomized, double-blind phase IIb/III trials and described as a reduction in newly acquired HIV…

Methodology · Statistics 2024-10-10 Yutong Jin , Alex Luedtke , Zoe Moodie , Holly Janes , David Benkeser

In this paper we discuss how to evaluate the differences between fitted logistic regression models across sub-populations. Our motivating example is in studying computerized diagnosis for learning disabilities, where sub-populations based…

Methodology · Statistics 2023-03-24 Guy Ashiri-Prossner , Yuval Benjamini

Objective. To pilot test an artificial intelligence (AI) algorithm that selects peer change agents (PCA) to disseminate HIV testing messaging in a population of homeless youth. Methods. We recruited and assessed 62 youth at baseline, 1…

Artificial Intelligence · Computer Science 2016-08-22 Eric Rice , Robin Petering , Jaih Craddock , Amanda Yoshioka-Maxwell , Amulya Yadav , Milind Tambe

In this paper we generalise a simple discrete time stochastic SIR type model defined by Tuckwell and Williams. The SIR model by Tuckwell and Williams assumes a homogeneous population, a fixed infectious period, and a strict transition from…

Populations and Evolution · Quantitative Biology 2025-04-21 Carles Rovira

Emerging infectious diseases are existential threats to human health and global stability. The recent outbreaks of the novel coronavirus COVID-19 have rapidly formed a global pandemic, causing hundreds of thousands of infections and huge…

Applications · Statistics 2020-06-02 Chuansai Zhou , Wen Yuan , Jun Wang , Haiyong Xu , Yong Jiang , Xinmin Wang , Qiuzi Han Wen , Pingwen Zhang

The two-phase sampling design is a cost-effective strategy widely used in public health research. Analyzing the Phase II sample often involves creating subsample-specific weights. However, these weights can be highly variable, leading to…

Methodology · Statistics 2026-04-07 Xinru Wang , Anyu Zhu , Lauren Kennedy , Abigail Greenleaf , Qixuan Chen