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As the development of new classes of antibiotics slows, bacterial resistance to existing antibiotics is becoming an increasing problem. A potential solution is to develop treatment strategies with an alternative mode of action. We consider…

Cell Behavior · Quantitative Biology 2018-07-04 Paul A. Roberts , Ryan M. Huebinger , Emma Keen , Anne-Marie Krachler , Sara Jabbari

The great flexibility of direct laser writing arises from the possibility to fabricate precise three-dimensional structures on very small scales as well as the broad range of applicable materials. However, there is still a vast number of…

Microscopic organisms, such as bacteria, have the ability of colonizing surfaces and developing biofilms that can determine diseases and infections. Most bacteria secrete a significant amount of extracellular polymer substances that are…

Biological Physics · Physics 2021-05-19 Francisco Javier Lobo-Cabrera , Alessandro Patti , Fernando Govantes , Alejandro Cuetos

Formamide (NH$_2$CHO), a potential prebiotic precursor, has been proposed to play an important role in the context of origin of life on our planet. It has been observed in different environments in space including the protostellar regions…

Instrumentation and Methods for Astrophysics · Physics 2022-06-22 T. Suhasaria , V. Mennella

Ribosomal protein S30 (RS30) exhibits potent antimicrobial activity against a broad spectrum of bacteria. Despite its efficacy, the underlying action mechanism remained elusive. In this study, we unravel the fundamental mechanism by which…

Soft Condensed Matter · Physics 2025-05-12 J. Bhatt Mitra , V. K. Sharma , M. Kumar , V. Garcia Sakai , A. Mukherjee

This study explores the physicochemical modifications and antimicrobial potential of plasma activated saline generated by exposing Sodium Chloride and Ringer solution to atmospheric pressure dielectric barrier discharge plasma. Plasma…

Plasma Physics · Physics 2026-01-07 Punit Kumar , Priti Saxena

Antimicrobial photodynamic therapy (aPDT) is a promising modality for inactivation of antibiotic resistant bacteria, relying on the activation of a photosensitizer (PS) by light of a specific wavelength. This process results in the…

Full control of molecular interactions, including reactive losses, would open new frontiers in quantum science. Here, we demonstrate extreme tunability of chemical reaction rates by using an external electric field to shift excited…

Microbes and pathogens play a detrimental role in healing wounds, causing infections like impetigo through bodily fluids and skin and entering the bloodstream through the wounds, thereby hindering the healing process and tissue…

Biomolecules · Quantitative Biology 2025-02-24 Suvash Ghimire , Yi Wu , Manjyot Kaur Chug , Elizabeth J. Brisbois , Kyungtae Kim , Kausik Mukhopadhyay

Access to intrinsic properties of a 2D material is challenging due to the absence of a bulk that would dominate over surface contamination, and this lack of bulk also precludes effective conventional cleaning methods that are almost always…

Materials Science · Physics 2024-10-28 Hao Wang , Milinda Randeniya , Austin Houston , Gerd Duscher , Gong Gu

Non-invasive optical manipulation of particles has emerged as a powerful and versatile tool for biological study and nanotechnology. In particular, trapping and rotation of cells, cell nuclei and sub-micron particles enables unique…

Aromaticity is a common chemical functionalities in bioactive molecules. In interstellar and circumstellar environments benzene and other small aromatics are considered the precursor for more complex prebiotic molecules and they have shown…

Instrumentation and Methods for Astrophysics · Physics 2025-10-14 Elettra L. Piacentino , Aurelia Balkanski , Jenny Calahan , Anna Fitzsimmons , Mahesh Rajappan , Karin I. Oberg

When disperse in biological fluids, engineered nanoparticles are selectively coated with proteins, resulting in the formation of a protein corona. It is suggested that the protein corona is critical in regulating the conditions of entry…

Materials Science · Physics 2021-09-21 V. Torrisi , A. Graillot , L. Vitorazi , Q. Crouzet , G. Marletta , C. Loubat , J. -F. Berret

Understanding the biophysical and magnetic interactions of nanoparticles (NPs) with cell mem-branes is critical for developing effective nanocarrier systems for drug delivery applications and targeted nanophysics applications. Recent…

Biological Physics · Physics 2022-08-08 Enrico Catalano

We introduce a new image cytometer design for detection of very small particulate and demonstrate its capability in water analysis. The device is a compact microscope composed of off the shelf components, such as a light emitting diode…

Optics · Physics 2016-02-17 Juan Miguel Pérez , Marc Jofre , Pedro Martínez , Valerio Pruneri

Microtubules are biological protein polymers with critical and diverse functions. Their structures share some similarities with photosynthetic antenna complexes, particularly in the ordered arrangement of photoactive molecules with large…

Biological Physics · Physics 2019-02-20 G. L. Celardo , M. Angeli , P. Kurian , T. J. A. Craddock

(Abridged) Complex organic molecules (COMs) are considered essential precursors to prebiotic species. While COMs were once expected to be efficiently destroyed under UV-irradiated conditions, detections in photodissociation regions (PDRs)…

In the search for novel nanostructured materials for UV plasmonics a limited number of choices can be done. Materials such as aluminum, rhodium, gallium and few others can be used. One of the most interesting application for UV plasmonics…

Polymers have appealing optical, biochemical, and mechanical qualities, including broadband transparency, ease of functionalization, and biocompatibility. However, their low refractive indices have precluded wavelength-scale optical…

Optics · Physics 2013-07-23 Xuetao Gan , Hannah Clevenson , Cheng-Chia Tsai , Luozhou Li , Dirk Englund

In a recent publication, we have highlighted the potential of phosphonic acid terminated PEG oligomers to functionalize strong UV absorption cerium oxide nanoparticles[1], which yield suspensions that are stable in aqueous or organic…

Materials Science · Physics 2013-05-07 L. Qi , J. Fresnais , P. Muller , O. Theodoly , J. -F. Berret , J. -P. Chapel