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This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Optimization and Control · Mathematics 2020-08-20 Mauricio C. de Oliveira

Viruses causing flu or milder coronavirus colds are often referred to as "seasonal viruses" as they tend to subside in warmer months. In other words, meteorological conditions tend to impact the activity of viruses, and this information can…

Respondent-driven sampling (RDS) is a popular method for sampling hard-to-survey populations that leverages social network connections through peer recruitment. While RDS is most frequently applied to estimate the prevalence of infections…

Methodology · Statistics 2016-10-24 Ashton M. Verdery , Jacob C. Fisher , Nalyn Siripong , Kahina Abdesselam , Shawn Bauldry

In regard to infectious diseases socioeconomic determinants are strongly associated with differential exposure and susceptibility however they are seldom accounted for by standard compartmental infectious disease models. These associations…

Applications · Statistics 2022-11-28 Alison C Hale , Jonathan M Read , Christopher P Jewell

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

Epidemics are a serious public health threat, and the resources for mitigating their effects are typically limited. Decision-makers face challenges in forecasting the supply and demand for these resources as prior information about the…

When multiple investigators analyze a common dataset, the data reuse induces dependence across testing procedures, affecting the distribution of errors. Existing techniques of managing dependent tests require either cross-study coordination…

Statistics Theory · Mathematics 2026-04-10 Reid Dale , Jordan Rodu , Maria E. Currie , Mike Baiocchi

Propensity score weighting approaches have been widely implemented in clinical research to estimate the effects of a treatment or exposure while mitigating the risk of confounding in the absence of random assignment. In practice, when…

Methodology · Statistics 2026-04-17 Emma K. Mackay , Amol A. Verma , Fahad Razak , Surain B. Roberts

Given the urgent informational needs connected with the diffusion of infection with regard to the COVID-19 pandemic, in this paper, we propose a sampling design for building a continuous-time surveillance system. Compared with other…

The frequent emergence of diseases with the potential to become threats at local and global scales, such as influenza A(H1N1), SARS, MERS, and recently COVID-19 disease, makes it crucial to keep designing models of disease propagation and…

Physics and Society · Physics 2020-08-27 I. A. Perez , M. A. Di Muro , C. E. La Rocca , L. A. Braunstein

Group testing was conceived during World War II to identify soldiers infected with syphilis using as few tests as possible, and it has attracted renewed interest during the COVID-19 pandemic. A long-standing assumption in the probabilistic…

Social and Information Networks · Computer Science 2022-11-18 Surin Ahn , Wei-Ning Chen , Ayfer Ozgur

Causal inference is crucial for understanding the true impact of interventions, policies, or actions, enabling informed decision-making and providing insights into the underlying mechanisms that shape our world. In this paper, we establish…

Methodology · Statistics 2024-03-26 Jingyue Huang , Changbao Wu , Leilei Zeng

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

Populations and Evolution · Quantitative Biology 2021-01-27 Timo de Wolff , Dirk Pflüger , Michael Rehme , Janin Heuer , Martin-Immanuel Bittner

Since the inception of the SARS - CoV - 2 (COVID - 19) novel coronavirus, a lot of time and effort is being allocated to estimate the trajectory and possibly, forecast with a reasonable degree of accuracy, the number of cases, recoveries,…

Applications · Statistics 2024-05-21 Agniva Das , Kunnummal Muralidharan

Propensity score methods are increasingly being used to reduce estimation bias of treatment effects for observational studies. Previous research has shown that propensity score methods consistently estimate the marginal hazard ratio for…

Methodology · Statistics 2019-11-19 Haodi Liang , Cecilia Cotton

Survival outcomes are common in comparative effectiveness studies and require unique handling because they are usually incompletely observed due to right-censoring. A ``once for all'' approach for causal inference with survival outcomes…

Methodology · Statistics 2021-12-21 Shuxi Zeng , Fan Li , Liangyuan Hu , Fan Li

In this paper, we study the effectiveness of the modelling approach on the pandemic due to the spreading of the novel COVID-19 disease and develop a susceptible-infected-removed (SIR) model that provides a theoretical framework to…

Populations and Evolution · Quantitative Biology 2020-08-26 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

Efficient estimation of population size from dependent dual-record system (DRS) remains a statistical challenge in capture-recapture type experiment. Owing to the nonidentifiability of the suitable Time-Behavioral Response Variation model…

Methodology · Statistics 2020-08-10 Kiranmoy Chatterjee , Diganta Mukherjee

The present paper introduces a new model used to study and analyse the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) epidemic-reported-data from Spain. This is a Hidden Markov Model whose hidden layer is a regeneration process…

We develop an agent-based model to assess the cumulative number of deaths during hypothetical Covid-19-like epidemics for various non-pharmaceutical intervention strategies. We consider local and non-local modes of disease transmission. The…

Physics and Society · Physics 2020-11-16 Zdzislaw Burda