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In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

Populations and Evolution · Quantitative Biology 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

COVID-19 pandemic is an ongoing global pandemic which has caused unprecedented disruptions in the public health sector and global economy. The virus, SARS-CoV-2 is responsible for the rapid transmission of coronavirus disease. Due to its…

Medical diagnostic testing can be made significantly more efficient using pooled testing protocols. These typically require a sparse infection signal and use either binary or real-valued entries of O(1). However, existing methods do not…

Statistical Mechanics · Physics 2024-03-15 Mansoor Sheikh , David Saad

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

This study introduces a stochastic model of COVID-19 transmission tailored to the Colorado School of Mines campus and evaluates surveillance testing strategies within a university context. Enhancing the conventional SEIR framework with…

Applications · Statistics 2024-04-09 Laura Albrecht , Karin Leiderman , Suzanne Sindi , Douglas Nychka

Problem definition: We study a workforce redeployment problem in hospital networks, where clinical staff, such as nurses, are temporarily reassigned from overstaffed to understaffed sites to address short-term imbalances. This practice of…

Optimization and Control · Mathematics 2025-09-10 Wei Liu , Tianchun Li , Mengshi Lu , Pengyi Shi

Causal or unconfounded descriptive comparisons between multiple groups are common in observational studies. Motivated from a racial disparity study in health services research, we propose a unified propensity score weighting framework, the…

Methodology · Statistics 2019-07-10 Fan Li , Fan Li

Multilevel regression and poststratification (MRP) is a popular method for addressing selection bias in subgroup estimation, with broad applications across fields from social sciences to public health. In this paper, we examine the…

Methodology · Statistics 2023-03-06 Yajuan Si

Since the first case of COVID-19 disease in Wuhan in December 2019, there is a worldwide struggle to reduce the transmission of acute respiratory syndrome coronavirus SARS-CoV-2. Many countries worldwide decided to impose local lockdowns in…

Other Quantitative Biology · Quantitative Biology 2022-08-09 Daniela Dobrynin , Iryna Polishchuk , Boaz Pokroy

Wastewater surveillance has proven to be a useful tool to monitor pathogens such as SARS-CoV-2 as it is a nonintrusive way to survey the potential disease burden of the population contributing to a sewershed. With the expansion of this…

We are currently facing a highly critical case of a world-wide pandemic. The novel coronavirus (SARS-CoV-2, a.k.a. COVID-19) has proved to be extremely contagious and the original outbreak from Asia has now spread to all continents. This…

Physics and Society · Physics 2020-06-26 Priyanka , Vicky Verma

Cross-sectional incidence estimation based on recency testing has become a widely used tool in HIV research. Recently, this method has gained prominence in HIV prevention trials to estimate the "placebo" incidence that participants might…

Methodology · Statistics 2024-12-18 Jianan Pan , Marlena Bannick , Fei Gao

The ability to directly record human face-to-face interactions increasingly enables the development of detailed data-driven models for the spread of directly transmitted infectious diseases at the scale of individuals. Complete coverage of…

Many epidemiologic studies forgo probability sampling and turn to nonprobability volunteer-based samples because of cost, response burden, and invasiveness of biological samples. However, finite population inference is difficult to make…

Applications · Statistics 2021-03-01 Lingxiao Wang , Richard Valliant , Yan Li

We propose a compressed sensing-based testing approach with a practical measurement design and a tuning-free and noise-robust algorithm for detecting infected persons. Compressed sensing results can be used to provably detect a small number…

Information Theory · Computer Science 2023-05-15 Hendrik Bernd Petersen , Bubacarr Bah , Peter Jung

The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…

Machine Learning · Computer Science 2020-07-28 Rahul Singh , Fang Liu , Ness B. Shroff

Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the…

Collaboration between different data centers is often challenged by heterogeneity across sites. To account for the heterogeneity, the state-of-the-art method is to re-weight the covariate distributions in each site to match the distribution…

Machine Learning · Statistics 2024-04-25 Tianyu Guo , Sai Praneeth Karimireddy , Michael I. Jordan

SARS-COV-19 is the most prominent issue which many countries face today. The frequent changes in infections, recovered and deaths represents the dynamic nature of this pandemic. It is very crucial to predict the spreading rate of this virus…

Populations and Evolution · Quantitative Biology 2023-02-01 Sadhana Tiwari , Ritesh Chandra , Sonali Agarwal
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