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In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

The call for patient-focused drug development is loud and clear, as expressed in the 21st Century Cures Act and in recent guidelines and initiatives of regulatory agencies. Among the factors contributing to modernized drug development and…

Adaptive monitoring of a large population of dynamic processes is critical for the timely detection of abnormal events under limited resources in many healthcare and engineering systems. Examples include the risk-based disease screening and…

Machine Learning · Computer Science 2023-10-24 Tanapol Kosolwattana , Huazheng Wang , Ying Lin

Electronic Health Records (EHRs) contain rich temporal dynamics that conventional encoding approaches fail to adequately capture. While Large Language Models (LLMs) show promise for EHR modeling, they struggle to reason about sequential…

Artificial Intelligence · Computer Science 2025-10-01 Zekai Chen , Arda Pekis , Kevin Brown

Most cognitive architectures rely on discrete representation, both in space (e.g., objects) and in time (e.g., events). However, a robot interaction with the world is inherently continuous, both in space and in time. The segmentation of the…

Robotics · Computer Science 2016-11-25 Bruno Nery , Rodrigo Ventura

Process analytics is an umbrella of data-driven techniques which includes making predictions for individual process instances or overall process models. At the instance level, various novel techniques have been recently devised, tackling…

Machine Learning · Computer Science 2021-07-29 Johannes De Smedt , Anton Yeshchenko , Artem Polyvyanyy , Jochen De Weerdt , Jan Mendling

One of the key challenges when developing a predictive model is the capability to describe the domain knowledge and the cause-effect relationships in a simple way. Decision rules are a useful and important methodology in this context,…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

The large volumes of data generated by human activities such as online purchases, health records, spatial mobility etc. are stored as a sequence of events over a continuous time. Learning deep learning methods over such sequences is a…

Machine Learning · Computer Science 2021-11-16 Vinayak Gupta

Sepsis is a life-threatening condition that seriously endangers millions of people over the world. Hopefully, with the widespread availability of electronic health records (EHR), predictive models that can effectively deal with clinical…

Machine Learning · Computer Science 2019-10-16 Luchen Liu , Haoxian Wu , Zichang Wang , Zequn Liu , Ming Zhang

Patient scheduling is a difficult task involving stochastic factors such as the unknown arrival times of patients. Similarly, the scheduling of radiotherapy for cancer treatments needs to handle patients with different urgency levels when…

Machine Learning · Computer Science 2022-10-25 Tu-San Pham , Antoine Legrain , Patrick De Causmaecker , Louis-Martin Rousseau

Individual-level human mobility prediction has emerged as a significant topic of research with applications in infectious disease monitoring, child, and elderly care. Existing studies predominantly focus on the microscopic aspects of human…

Machine Learning · Computer Science 2025-08-20 Yueyang Liu , Lance Kennedy , Ruochen Kong , Joon-Seok Kim , Andreas Züfle

Complex deep learning models show high prediction tasks in various clinical prediction tasks but their inherent complexity makes it more challenging to explain model predictions for clinicians and healthcare providers. Existing research on…

Machine Learning · Computer Science 2026-02-06 Sayantan Kumar , Sean C. Yu , Thomas Kannampallil , Zachary Abrams , Andrew Michelson , Philip R. O. Payne

Health management has become a primary problem as new kinds of diseases and complex symptoms are introduced to a rapidly growing modern society. Building a better and smarter healthcare infrastructure is one of the ultimate goals of a smart…

Machine Learning · Computer Science 2025-03-24 Chu Myaet Thwal , Kyi Thar , Ye Lin Tun , Choong Seon Hong

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

Machine Learning · Computer Science 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

The abundance of data affords researchers to pursue more powerful computational tools to learn the dynamics of complex system, such as neural networks, engineered systems and social networks. Traditional machine learning approaches capture…

Machine Learning · Computer Science 2024-05-16 Yan Shen , Fan Yang , Mingchen Gao , Wen Dong

The individual data collected throughout patient follow-up constitute crucial information for assessing the risk of a clinical event, and eventually for adapting a therapeutic strategy. Joint models and landmark models have been proposed to…

Machine Learning · Statistics 2024-07-17 Anthony Devaux , Robin Genuer , Karine Pérès , Cécile Proust-Lima

Online healthcare consultations have transformed how patients seek medical advice, offering convenience while introducing new challenges for ensuring consultation success. Predicting whether an online consultation will be successful is…

Machine Learning · Computer Science 2025-11-03 Shuang Geng , Wenli Zhang , Jiaheng Xie , Gemin Liang , Ben Niu , Sudha Ram

User interests are usually dynamic in the real world, which poses both theoretical and practical challenges for learning accurate preferences from rich behavior data. Among existing user behavior modeling solutions, attention networks are…

Information Retrieval · Computer Science 2022-04-14 Chao Chen , Haoyu Geng , Nianzu Yang , Junchi Yan , Daiyue Xue , Jianping Yu , Xiaokang Yang

COVID-19 has challenged health systems to learn how to learn. This paper describes the context, methods and challenges for learning to improve COVID-19 care at one academic health center. Challenges to learning include: (1) choosing a right…