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Trustworthiness is a central requirement for the acceptance and success of human-centered artificial intelligence (AI). To deem an AI system as trustworthy, it is crucial to assess its behaviour and characteristics against a gold standard…

Artificial intelligence and machine learning are reshaping how we approach scientific discovery, not by replacing established methods but by extending what researchers can probe, predict, and design. In this roadmap we provide a…

Existing alignment research is dominated by concerns about safety and preventing harm: safeguards, controllability, and compliance. This paradigm of alignment parallels early psychology's focus on mental illness: necessary but incomplete.…

We introduce the fundamental ideas and challenges of Predictable AI, a nascent research area that explores the ways in which we can anticipate key validity indicators (e.g., performance, safety) of present and future AI ecosystems. We argue…

Collaborative AI systems aim at working together with humans in a shared space to achieve a common goal. This setting imposes potentially hazardous circumstances due to contacts that could harm human beings. Thus, building such systems with…

Software Engineering · Computer Science 2021-03-15 Matteo Camilli , Michael Felderer , Andrea Giusti , Dominik T. Matt , Anna Perini , Barbara Russo , Angelo Susi

This paper introduces Lean 5.0, a human-centric evolution of Lean-Digital integration that connects predictive analytics, AI collaboration, and continuous learning within Industry 5.0 and Construction 5.0 contexts. A systematic literature…

Computational Engineering, Finance, and Science · Computer Science 2025-11-25 Atena Khoshkonesh , Mohsen Mohammadagha , Navid Ebrahimi , Narges Sadeghigolshan

With the rise of AI systems in real-world applications comes the need for reliable and trustworthy AI. An essential aspect of this are explainable AI systems. However, there is no agreed standard on how explainable AI systems should be…

Artificial Intelligence · Computer Science 2022-07-04 Sascha Saralajew , Ammar Shaker , Zhao Xu , Kiril Gashteovski , Bhushan Kotnis , Wiem Ben Rim , Jürgen Quittek , Carolin Lawrence

The integration of Artificial Intelligence (AI) into clinical settings presents a software engineering challenge, demanding a shift from isolated models to robust, governable, and reliable systems. However, brittle, prototype-derived…

Human computer interaction is shifting from screen-based systems to multimodal interfaces where artificial intelligence powered systems increasingly interpret user intent through speech, gesture, and gaze. Yet users rarely understand how…

Human-Computer Interaction · Computer Science 2026-05-05 Ankur Bhatt , Sven Mayer

Artificial Intelligence based systems increasingly use personalization to provide users with relevant content, products, and solutions. Personalization is intended to support users and address their respective needs and preferences.…

Computers and Society · Computer Science 2020-08-24 Laura Schelenz , Avi Segal , Kobi Gal

Enterprise AI systems, built on large language models, retrieval pipelines and autonomous agents, introduce a class of risks that traditional software quality assurance was never designed to address. These systems are probabilistic,…

Software Engineering · Computer Science 2026-05-25 Chitra Badagi , Divye Singh , Animesh Sen , Adinath Shirsath

The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…

Physics and Society · Physics 2025-10-07 Alex Zhavoronkov , Chuen Yan Leung

Safety cases, structured arguments that a system is acceptably safe, are becoming central to the governance of AI systems. Yet, traditional safety-case practices from aviation or nuclear engineering rely on well-specified system boundaries,…

Software Engineering · Computer Science 2026-03-09 Sung Une Lee , Liming Zhu , Md Shamsujjoha , Liming Dong , Qinghua Lu , Jieshan Chen , Lionel Briand

Trust in clinical artificial intelligence (AI) cannot be reduced to model accuracy, fluency of generation, or overall positive user impression. In medicine, trust must be engineered as a measurable system property grounded in evidence,…

Computation and Language · Computer Science 2026-04-30 Serhii Zabolotnii , Viktoriia Holinko , Olha Antonenko

Artificial Intelligence is one of the fastest growing technologies of the 21st century and accompanies us in our daily lives when interacting with technical applications. However, reliance on such technical systems is crucial for their…

The convergence of artificial intelligence, cyber-physical systems, and cross-enterprise data ecosystems has propelled industrial intelligence to unprecedented scales. Yet, the absence of a unified trust foundation across data, services,…

Computational Engineering, Finance, and Science · Computer Science 2026-01-09 Hailiang Zhao , Ziqi Wang , Daojiang Hu , Zhiwei Ling , Wenzhuo Qian , Jiahui Zhai , Yuhao Yang , Zhipeng Gao , Mingyi Liu , Kai Di , Xinkui Zhao , Zhongjie Wang , Jianwei Yin , MengChu Zhou , Shuiguang Deng

Embedding artificial intelligence into systems introduces significant challenges to modern engineering practices. Hazard analysis tools and processes have not yet been adequately adapted to the new paradigm. This paper describes initial…

Software Engineering · Computer Science 2022-03-30 Nikolas Martelaro , Carol J. Smith , Tamara Zilovic

Artificial intelligence (AI) has brought benefits, but it may also cause harm if it is not appropriately developed. Current development is mainly driven by a "technology-centered" approach, causing many failures. For example, the AI…

Human-Computer Interaction · Computer Science 2023-02-21 Wei Xu , Marvin Dainoff

The integration of Artificial Intelligence (AI) into automation systems has the potential to enhance efficiency and to address currently unsolved existing technical challenges. However, the industry-wide adoption of AI is hindered by the…

Systems and Control · Electrical Eng. & Systems 2024-07-04 Marvin Schieseck , Philip Topalis , Lasse Reinpold , Felix Gehlhoff , Alexander Fay

This paper investigates how artificial intelligence (AI) can be effectively integrated into Strategic Technology Management (STM) practices to enhance the strategic alignment and effectiveness of technology investments. Through a…

Human-Computer Interaction · Computer Science 2025-12-11 Massimo Fascinari , Vincent English
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