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Purpose: To implement and evaluate a new dictionary-based technique for native myocardial T1 and T2 mapping using Cartesian sampling. Methods: The proposed technique (Multimapping) consisted of single-shot Cartesian image acquisitions in 10…

Medical Physics · Physics 2022-01-05 Markus Henningsson

Background: Accurate myocardial T1 mapping at 5T remains a technical challenge due to field inhomogeneity and prolonged T1 values. The aim of this study is to develop an accurate and clinically applicable myocardial T1 mapping technique for…

Cardiac T1 mapping is a valuable quantitative MRI technique for diagnosing diffuse myocardial diseases. Traditional methods, relying on breath-hold sequences and cardiac triggering based on an ECG signal, face challenges with patient…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Eyal Hanania , Adi Zehavi-Lenz , Ilya Volovik , Daphna Link-Sourani , Israel Cohen , Moti Freiman

Purpose: To develop a new sequence, MIMOSA, for highly-efficient T1, T2, T2*, proton density (PD), and source separation quantitative susceptibility mapping (QSM). Methods: MIMOSA was developed based on 3D-quantification using an…

Purpose: To develop a cardiac T1 mapping method for free-breathing 3D T1 mapping of the whole heart at 3T with transmit B1 (B1+) correction Methods: A free-breathing, ECG-gated inversion recovery sequence with spoiled gradient-echo readout…

Medical Physics · Physics 2021-11-16 Paul Kyu Han , Thibault Marin , Yanis Djebra , Vanessa Landes , Yue Zhuo , Georges El Fakhri , Chao Ma

Purpose: To develop and evaluate a cardiovascular magnetic resonance sequence (MyoFold) for rapid myocardial tissue and movement characterization. Method: MyoFold sequentially performs joint T1/T2 mapping and cine for one left-ventricle…

Objective: To develop an accurate myocardial T1 mapping technique at 5T using Look-Locker-based multiple inversion-recovery with the real-time spoiled gradient echo (GRE) acquisition. Approach: The proposed T1 mapping technique (mIR-rt)…

Medical Physics · Physics 2025-08-29 Linqi Ge , Yihang Zhang , Huibin Zhu , Lang Zhang , Yihang Zhou , Haifeng Wang , Dong Liang , Hairong Zheng , Yanjie Zhu

Purpose: Magnetization transfer saturation (MTsat) mapping is commonly used to examine the macromolecular content of brain tissue. This study compared variable flip angle (VFA) T1 mapping against compressed sensing (cs)MP2RAGE T1 mapping…

Purpose: To develop a free-breathing myocardial T1 mapping technique using inversion-recovery (IR) radial fast low-angle shot (FLASH) and calibrationless motion-resolved model-based reconstruction. Methods: Free-running (free-breathing,…

Low-field T2 mapping MRI can democratize neuropediatric imaging by improving accessibility and providing quantitative biomarkers of brain development. \textbf{Purpose:} To evaluate the feasibility of high-resolution T2 mapping using a…

Cardiac T1 mapping provides critical quantitative insights into myocardial tissue composition, enabling the assessment of pathologies such as fibrosis, inflammation, and edema. However, the inherently dynamic nature of the heart imposes…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Tamir Shor , Moti Freiman , Chaim Baskin , Alex Bronstein

Purpose: To develop and evaluate MyoMapNet, a rapid myocardial T1 mapping approach that uses neural networks (NN) to estimate voxel-wise myocardial T1 and extracellular (ECV) from T1-weighted images collected after a single inversion pulse…

Medical Physics · Physics 2021-04-02 Hossam El-Rewaidy , Rui Guo , Amanda Paskavitz , Tuyen Yankama , Long Ngo , Bjoern Menze , Reza Nezafat

T1 mapping is a quantitative magnetic resonance imaging (qMRI) technique that has emerged as a valuable tool in the diagnosis of diffuse myocardial diseases. However, prevailing approaches have relied heavily on breath-hold sequences to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Eyal Hanania , Ilya Volovik , Lilach Barkat , Israel Cohen , Moti Freiman

While typical qualitative T1-weighted magnetic resonance images reflect scanner and protocol differences, quantitative T1 mapping aims to measure T1 independent of these effects. Changes in T1 in the brain reflect structural changes in…

A model-based reconstruction framework is proposed for MOtion-Corrected and High-resolution anatomically-Assisted (MOCHA) reconstruction of ASL data. In this framework, all low-resolution ASL control-label pairs are used to reconstruct a…

Purpose: To develop a single-shot multi-slice T1 mapping method by combing simultaneous multi-slice (SMS) excitations, single-shot inversion-recovery (IR) radial fast low-angle shot (FLASH) and a nonlinear model-based reconstruction method.…

Purpose: To develop and evaluate a free-breathing respiratory motion compensated 4D (3D+respiration) $T_2$-weighted turbo spin echo sequence with application to radiology and MR-guided radiotherapy. Methods: k-space data are continuously…

Purpose: To develop and evaluate a method for rapid estimation of multiparametric T1, T2, proton density (PD), and inversion efficiency (IE) maps from 3D-quantification using an interleaved Look-Locker acquisition sequence with T2…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Yohan Jun , Jaejin Cho , Xiaoqing Wang , Michael Gee , P. Ellen Grant , Berkin Bilgic , Borjan Gagoski

Myocardial T1 mapping is a cardiac MRI technique, used to assess myocardial fibrosis. In this technique, a series of T1-weighted MRI images are acquired with different saturation or inversion times. These images are fitted to the T1 model…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Dar Arava , Mohammad Masarwy , Samah Khawaled , Moti Freiman

Purpose: To develop an accelerated Cartesian MRF implementation using a multi-shot EPI sequence for rapid simultaneous quantification of T1 and T2 parameters. Methods: The proposed Cartesian MRF method involved the acquisition of highly…

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