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Purpose: This study aims to develop a high-resolution whole-brain multi-parametric quantitative MRI approach for simultaneous mapping of myelin-water fraction (MWF), T1, T2, and proton-density (PD), all within a clinically feasible scan…

Purpose: To improve the accuracy of multiparametric estimation, including myelin water fraction (MWF) quantification, and reduce scan time in 3D-QALAS by optimizing sequence parameters, using a self-supervised multilayer perceptron network.…

Multicomponent T2-mapping using a gradient and spin-echo (GraSE) acquisition has become standard for myelin water imaging at 3T. Higher magnetic field strengths promise SNR benefits but face specific absorption rate limits and shortened T2…

Medical Physics · Physics 2021-05-14 Vanessa Wiggermann , Alex MacKay , Alexander Rauscher , Gunther Helms

The anisotropic nature of short-axis (SAX) cardiovascular magnetic resonance imaging (CMRI) limits cardiac shape analysis. To address this, we propose to leverage near-isotropic, higher resolution computed tomography angiography (CTA) data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Carolina Brás , Soufiane Ben Haddou , Thijs P. Kuipers , Laura Alvarez-Florez , R. Nils Planken , Fleur V. Y. Tjong , Connie Bezzina , Ivana Išgum

$\textbf{Purpose:}$ To develop a new method for free-breathing 3D extracellular volume (ECV) mapping of the whole heart at 3T. $\textbf{Methods:}$ A free-breathing 3D cardiac ECV mapping method was developed at 3T. T1 mapping was performed…

Purpose: Designing a new T2 preparation (T2-Prep) module in order to simultaneously provide robust fat suppression and efficient T2 preparation without requiring an additional fat suppression module for T2-weighted imaging at 3T. Methods:…

Medical Physics · Physics 2022-11-04 Lionel Arn , Ruud B van Heeswijk , Matthias Stuber , Jessica AM Bastiaansen

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright

Spatial-Spectral Mamba (SSM) improves computational efficiency and captures long-range dependencies, addressing Transformer limitations. However, traditional Mamba models overlook rich spectral information in HSIs and struggle with high…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Muhammad Ahmad , Muhammad Hassaan Farooq Butt , Muhammad Usama , Hamad Ahmed Altuwaijri , Manuel Mazzara , Salvatore Distefano

Purpose: To propose and evaluate an accelerated $T_{1\rho}$ quantification method that combines $T_{1\rho}$-weighted fast spin echo (FSE) images and proton density (PD)-weighted anatomical FSE images, leveraging deep learning models for…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Junru Zhong , Chaoxing Huang , Ziqiang Yu , Fan Xiao , Siyue Li , Tim-Yun Michael Ong , Ki-Wai Kevin Ho , Queenie Chan , James F. Griffith , Weitian Chen

Purpose: Echo modulation curve (EMC) modeling can provide accurate and reproducible quantification of T2 relaxation times. The standard EMC-T2 mapping framework, however, requires sufficient echoes and cumbersome pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Haoyang Pei , Timothy M. Shepherd , Yao Wang , Fang Liu , Daniel K Sodickson , Noam Ben-Eliezer , Li Feng

Quantitative magnetic resonance imaging might provide a more specific insight into disease process, progression and therapeutic response of multiple sclerosis. We present an extension of a previously published approach for the simultaneous…

Stochastic approximation (SA) that involves multiple coupled sequences, known as multiple-sequence SA (MSSA), finds diverse applications in the fields of signal processing and machine learning. However, existing theoretical understandings…

Machine Learning · Computer Science 2024-10-18 Yue Huang , Zhaoxian Wu , Shiqian Ma , Qing Ling

We developed a new magnetic resonance imaging method called multinuclear fingerprinting (MNF) which leverages simultaneously-acquired proton (1H) and sodium (23Na) data to generate seven quantitative maps of the whole brain: proton density…

Medical Physics · Physics 2026-05-25 Gonzalo G. Rodriguez , Zidan Yu , Lauren O'Donnell , Martijn A. Cloos , Guillaume Madelin

This paper proposes a statistical framework to optimize and evaluate the MR parameter $T_1$ and $T_2$ mapping capabilities for quantitative MRI relaxometry approaches. This analysis explores the intrinsic MR parameter estimate precision per…

Signal Processing · Electrical Eng. & Systems 2020-01-03 Yang Liu , John R. Buck , Shaokuan Zheng

OBJECTIVES: Quantitative MRI techniques such as T2 and T1$\rho$ mapping are beneficial in evaluating cartilage and meniscus. We aimed to evaluate the MIXTURE (Multi-Interleaved X-prepared Turbo-Spin Echo with IntUitive RElaxometry)…

Magnetic resonance fingerprinting (MRF) provides a unique concept for simultaneous and fast acquisition of multiple quantitative MR parameters. Despite acquisition efficiency, adoption of MRF into the clinics is hindered by its dictionary…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Fabian Balsiger , Alain Jungo , Olivier Scheidegger , Pierre G. Carlier , Mauricio Reyes , Benjamin Marty

This letter investigates the challenge of channel estimation in a multiuser millimeter-wave (mmWave) time-division duplexing (TDD) system. In this system, the base station (BS) employs a multi-antenna uniform linear array (ULA), while each…

Information Theory · Computer Science 2024-01-04 Hao Xu , Gui Zhou , Kai-Kit Wong , Wee Kiat New , Chao Wang , Chan-Byoung Chae , Ross Murch , Shi Jin , Yangyang Zhang

Purpose: To rapidly obtain high isotropic-resolution T2 maps with whole-brain coverage and high geometric fidelity. Methods: A T2 blip-up/down echo planar imaging (EPI) acquisition with generalized Slice-dithered enhanced resolution…

Proton magnetic resonance spectroscopic imaging (1H-MRSI) is a powerful tool that enables the multidimensional non-invasive mapping of the neurochemical profile at high-resolution over the entire brain. The constant demand for higher…

PURPOSE To develop free-running multi-echo GRE for cardiac- and respiratory-motion-resolved whole-heart fat fraction quantification. METHODS Multi-echo readouts optimized for water-fat separation and quantification were integrated within a…