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Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Salah A. Baker

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays,…

Computation and Language · Computer Science 2022-11-09 Loukas Ilias , Dimitris Askounis , John Psarras

Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite…

Tissues and Organs · Quantitative Biology 2015-06-15 Klas H. Pettersen , Scott M. Bugenhagen , Javaid Nauman , Daniel A. Beard , Stig W. Omholt

The segmentation of retinal vessels is of significance for doctors to diagnose the fundus diseases. However, existing methods have various problems in the segmentation of the retinal vessels, such as insufficient segmentation of retinal…

Computer Vision and Pattern Recognition · Computer Science 2018-05-14 Yun Jiang , Ning Tan

Diabetic Retinopathy (DR) is a complication of long-standing, unchecked diabetes and one of the leading causes of blindness in the world. This paper focuses on improved and robust methods to extract some of the features of DR, viz. Blood…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Soham Basu , Sayantan Mukherjee , Ankit Bhattacharya , Anindya Sen

Disease complications can alter vascular network morphology and disrupt tissue functioning. Diabetic retinopathy, for example, is a complication of types 1 and 2 diabetes mellitus that can cause blindness. Microvascular diseases are…

Quantitative Methods · Quantitative Biology 2022-09-13 John T. Nardini , Charles W. J. Pugh , Helen M. Byrne

Retinal Cysts are formed by leakage and accumulation of fluid in the retina due to the incompetence of retinal vasculature. These cystic spaces have significance in several ocular diseases such as age-related macular degeneration, diabetic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Abhishek Dharmaratnakar , Aadheeshwar Vijayakumar , Suchand Dayanand

During the aging of the red-blood cell, or under conditions of extreme echinocytosis, membrane is shed from the cell plasma membrane in the form of nano-vesicles. We propose that this process is the result of the self-adaptation of the…

Cell Behavior · Quantitative Biology 2015-06-26 Pierre Sens , Nir gov

Diabetic Retinopathy (DR) is a prominent cause of blindness in the world. The early treatment of DR can be conducted from detection of microaneurysms (MAs) which appears as reddish spots in retinal images. An automated microaneurysm…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Noushin Eftekheri , Mojtaba Masoudi , Hamidreza Pourreza , Kamaledin Ghiasi Shirazi , Ehsan Saeedi

This research aims to develop an efficient system for screening of diabetic retinopathy. Diabetic retinopathy is the major cause of blindness. Severity of diabetic retinopathy is recognized by some features, such as blood vessel area,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Faisal Ghaffar , Sarwar Khan , Bunyarit Uyyanonvara , Chanjira Sinthanayothin , Hirohiko Kaneko

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. Current grading systems based on imaging biomarkers only coarsely group disease stages into broad categories and are unable to predict future disease…

Objective: Diabetic macular edema (DME) is the leading cause of severe visual impairment in patients with diabetes. Quantification of retinal fluid, particularly intraretinal fluid (IRF) and subretinal fluid (SRF), plays a critical role in…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zijun Lei , Zikang Xu , Liang Zhang , Ge Song , Hanyu Guo , Dan Cao , Yujia Zhou , Qianjin Feng

Diabetic Retinopathy is a medical condition where the retina is damaged because fluid leaks from blood vessels into the retina. The presence of hemorrhages in the retina is the earliest symptom of diabetic retinopathy. The number and shape…

Computer Vision and Pattern Recognition · Computer Science 2013-10-23 Nidhal Khdhair El Abbadi , Enas Hamood Al Saadi

Due to over-metabolism, the tumour cells become hypoxic. To overcome this situation tumour cells secret several chemical substrates to attract nearby blood vessels towards it (angiogenesis). Transition from avascular to vascular tumour is…

Biological Physics · Physics 2019-09-06 Sounak Sadhukhan , S. K. Basu

In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Yifan Peng , Shazia Dharssi , Qingyu Chen , Tiarnan D. Keenan , Elvira Agrón , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Retinal blood vessels are considered to be the reliable diagnostic biomarkers of ophthalmologic and diabetic retinopathy. Monitoring and diagnosis totally depends on expert analysis of both thin and thick retinal vessels which has recently…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Waseem Abbas , Muhammad Haroon Shakeel , Numan Khurshid , Murtaza Taj

In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…

Quantitative Methods · Quantitative Biology 2020-03-11 Razvan V. Marinescu

Alzheimer's disease (AD) is a neurodegenerative disorder and the most common cause of dementia in the elderly. The extracellular accumulation of amyloid-$\beta$ (A$\beta$) in senile plaques is a principal event in the pathogenesis and there…

Medical Physics · Physics 2018-03-12 E. G. Lobanova , S. V. Lobanov , K. Triantafilou , W. Langbein , P. Borri

Temperature difference-induced mist adhered to the glass, such as windshield, camera lens, is often inhomogeneous and obscure, easily obstructing the vision and severely degrading the image. Together with adherent raindrops, they bring…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Da He , Xiaoyu Shang , Jiajia Luo
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