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Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Da He , De Cai , Jiasheng Zhou , Jiajia Luo , Sung-Liang Chen

In this paper, we propose a new deep learning framework for an automatic myocardial infarction evaluation from clinical information and delayed enhancement-MRI (DE-MRI). The proposed framework addresses two tasks. The first task is…

Image and Video Processing · Electrical Eng. & Systems 2020-11-02 Kibrom Berihu Girum , Youssef Skandarani , Raabid Hussain , Alexis Bozorg Grayeli , Gilles Créhange , Alain Lalande

Arterial spin labeling (ASL) allows to quantify the cerebral blood flow (CBF) by magnetic labeling of the arterial blood water. ASL is increasingly used in clinical studies due to its noninvasiveness, repeatability and benefits in…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Cagdas Ulas , Giles Tetteh , Stephan Kaczmarz , Christine Preibisch , Bjoern H. Menze

Dynamic positron emission tomography (PET) imaging combined with radiotracer kinetic modeling is a powerful technique for visualizing biological processes in the brain, offering valuable insights into brain functions and neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Junyu Chen , Zirui Jiang , Jennifer M. Coughlin , Ian Cheong , Kelly A. Mills , Martin G. Pomper , Yong Du

The precise segmentation of intracranial aneurysms and their parent vessels (IA-Vessel) is a critical step for hemodynamic analyses, which mainly depends on computational fluid dynamics (CFD). However, current segmentation methods…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Feiyang Xiao , Yichi Zhang , Xigui Li , Yuanye Zhou , Chen Jiang , Xin Guo , Limei Han , Yuxin Li , Fengping Zhu , Yuan Cheng

DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…

Quantitative Methods · Quantitative Biology 2025-10-17 Pierre Fayolle , Alexandre Bône , Noëlie Debs , Mathieu Naudin , Pascal Bourdon , Remy Guillevin , David Helbert

Precise ischemic lesion segmentation plays an essential role in improving diagnosis and treatment planning for ischemic stroke, one of the prevalent diseases with the highest mortality rate. While numerous deep neural network approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Luca Tomasetti , Stine Hansen , Mahdieh Khanmohammadi , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz , Michael Kampffmeyer

Variability of IVIM parameters throughout the literature is a long-standing issue, and perfusion-related parameters are difficult to interpret. We demonstrate for improving the analysis of intravoxel incoherent motion imaging (IVIM)…

Medical Physics · Physics 2024-01-05 Caleb Sample , Jonn Wu , Haley Clark

Automatic segmentation of myocardial contours and relevant areas like infraction and no-reflow is an important step for the quantitative evaluation of myocardial infarction. In this work, we propose a cascaded convolutional neural network…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Yichi Zhang

In the imaging process of an astronomical telescope, the deconvolution of its beam or Point Spread Function (PSF) is a crucial task. However, deconvolution presents a classical and challenging inverse computation problem. In scenarios where…

Instrumentation and Methods for Astrophysics · Physics 2024-03-05 Shulei Ni , Yisheng Qiu , Yunchun Chen , Zihao Song , Hao Chen , Xuejian Jiang , Huaxi Chen

Optical microscopy is an essential tool in biology and medicine. Imaging thin, yet non-flat objects in a single shot (without relying on more sophisticated sectioning setups) remains challenging as the shallow depth of field that comes with…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Adrian Shajkofci , Michael Liebling

Precise and fast prediction methods for ischemic areas comprised of dead tissue, core, and salvageable tissue, penumbra, in acute ischemic stroke (AIS) patients are of significant clinical interest. They play an essential role in improving…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Luca Tomasetti , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz , Mahdieh Khanmohammadi

Deconvolution of the telescope Point Spread Function (PSF) is necessary for even moderate dynamic range imaging with interferometric telescopes. The process of deconvolution can be treated as a search for a model image such that the…

Astrophysics · Physics 2009-11-10 S. Bhatnagar , T. J. Cornwell

Stroke is the second most common cause of death in developed countries, where rapid clinical intervention can have a major impact on a patient's life. To perform the revascularization procedure, the decision making of physicians considers…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Adriano Pinto , Sergio Pereira , Raphael Meier , Victor Alves , Roland Wiest , Carlos A. Silva , Mauricio Reyes

Predicting rupture risk and deciding on optimal treatment plan for intracranial aneurysms (IAs) is possible by quantification of their size and shape. For this purpose the IA has to be isolated from 3D angiogram. State-of-the-art methods…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Žiga Bizjak , Boštjan Likar , Franjo Pernuš , Žiga Špiclin

Diffusion-Weighted Magnetic Resonance Imaging (DWI) is widely used for early cerebral infarct detection caused by ischemic stroke. Manual segmentation is done by a radiologist as a common clinical process, nonetheless, challenges of…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Noranart Vesdapunt , Nongluk Covavisaruch

Distinguishing acute ischemic strokes (AIS) from stroke mimics (SMs), particularly in cases involving medium and small vessel occlusions, remains a significant diagnostic challenge. While computed tomography (CT) based protocols are…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Marijn Borghouts , Richard McKinley , Manuel Köstner , Josien Pluim , Roland Wiest , Ruisheng Su

Convolution and deconvolution are essential techniques in various fields, notably in medical imaging, where they play a crucial role in analyzing dynamic processes such as blood flow. This paper explores the convolution and deconvolution of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ishmael N. Amartey , Andreas A. Linninger , Thomas Ventimiglia

The impulse response function (IRF) of a localized bolus in cerebral blood flow codes important information on the tissue type. It is indirectly accessible both from MR- and CT-imaging methods, at least in principle. In practice, however,…

Tissues and Organs · Quantitative Biology 2014-09-30 Evelyn Rost , Ralf Geske , Michael Baake