Related papers: Differentiable Deconvolution for Improved Stroke P…
Perfusion imaging is crucial in acute ischemic stroke for quantifying the salvageable penumbra and irreversibly damaged core lesions. As such, it helps clinicians to decide on the optimal reperfusion treatment. In perfusion CT imaging,…
Deep-learning (DL)-based image deconvolution (ID) has exhibited remarkable recovery performance, surpassing traditional linear methods. However, unlike traditional ID approaches that rely on analytical properties of the point spread…
Purpose: In this study we investigate whether a Convolutional Neural Network (CNN) can generate clinically relevant parametric maps from CT perfusion data in a clinical setting of patients with acute ischemic stroke. Methods: Training of…
In this paper, an automatic algorithm aimed at volumetric segmentation of acute ischemic stroke lesion in non-contrast computed tomography brain 3D images is proposed. Our deep-learning approach is based on the popular 3D U-Net…
Quantification of myocardial perfusion has the potential to improve detection of regional and global flow reduction. Significant effort has been made to automate the workflow, where one essential step is the arterial input function (AIF)…
Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is widely used to evaluate acute ischemic stroke to distinguish salvageable tissue and infarct core. For this purpose, traditional methods employ deconvolution techniques,…
Intraoperative 2D quantitative angiography (QA) for intracranial aneurysms (IAs) has accuracy challenges due to the variability of hand injections. Despite the success of singular value decomposition (SVD) algorithms in reducing biases in…
More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…
Accurate detection of arterial input function is a crucial step in obtaining perfusion hemodynamic parameters using dynamic susceptibility contrast-enhanced magnetic resonance imaging. It is required as input for perfusion quantification…
CT Perfusion (CTP) imaging has gained importance in the diagnosis of acute stroke. Conventional perfusion analysis performs a deconvolution of the measurements and thresholds the perfusion parameters to determine the tissue status. We…
Delineating infarcted tissue in ischemic stroke lesions is crucial to determine the extend of damage and optimal treatment for this life-threatening condition. However, this problem remains challenging due to high variability of ischemic…
Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…
Perfusion imaging plays a crucial role in acute stroke diagnosis and treatment decision making. Current perfusion analysis relies on deconvolution of the measured signals, an operation that is mathematically ill-conditioned and requires…
Ischemic stroke lesion segmentation from Computed Tomography Perfusion (CTP) images is important for accurate diagnosis of stroke in acute care units. However, it is challenged by low image contrast and resolution of the perfusion parameter…
In this work, we present a novel convolutional neural net- work based method for perfusion map generation in dynamic suscepti- bility contrast-enhanced perfusion imaging. The proposed architecture is trained end-to-end and solely relies on…
This paper addresses the problem of high-resolution Doppler blood flow estimation from an ultrafast sequence of ultrasound images. Formulating the separation of clutter and blood components as an inverse problem has been shown in the…
Ultrasound is widely used in medical diagnostics allowing for accessible and powerful imaging but suffers from resolution limitations due to diffraction and the finite aperture of the imaging system, which restricts diagnostic use. The…
Inverse problems in image reconstruction are fundamentally complicated by unknown noise properties. Classical iterative deconvolution approaches amplify noise and require careful parameter selection for an optimal trade-off between…
Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…
The patient with ischemic stroke can benefit most from the earliest possible definitive diagnosis. While the high quality medical resources are quite scarce across the globe, an automated diagnostic tool is expected in analyzing the…