Related papers: Stability of Contraction-Driven Cell Motion
We introduce a two-dimensional Hele-Shaw type free boundary model for motility of eukaryotic cells on substrates. The key ingredients of this model are the Darcy law for overdamped motion of the cytoskeleton gel (active gel) coupled with…
We introduce a two-dimensional Keller-Segel type free boundary model for motility of eukaryotic cells on substrates. The key ingredients of this model are the Darcy law for overdamped motion of the cytoskeleton (active) gel and Hele-Shaw…
Contraction-driven self-propulsion of a large class of living cells can be modeled by a Keller-Segel system with free boundaries. The ensuing "active" system, exhibiting both dissipation and anti-dissipation, features stationary and…
We study a two-dimensional free boundary problem that models motility of eukaryotic cells on substrates. This problem consists of an elliptic equation describing the flow of cytoskeleton gel coupled with a convection-diffusion PDE for the…
Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…
We perform an analytical investigation of the cell interface dynamics in the framework of a minimal phase field model of cell motility suggested in [1], which consists of two coupled evolution equations for the order parameter and a…
We study an incompressible Darcy's free boundary problem, recently introduced in [22]. Our goal is to prove the existence of non-trivial traveling wave solutions and thus validate the interest of this model to describe cell motility. The…
The cell motility problem has been investigated for a long time. Today, many biologists, physicists, and mathematicians are looking for new research instruments for this process. A simple 2D model of a free-boundary cell moving on a…
In this paper, we present a cell motility model that takes into account the cell membrane effect. The model introduced is an incompressible Darcy free boundary problem. This model involves a nonlinear term in the boundary condition to model…
In this paper, we introduce a data-driven modeling approach for dynamics problems with latent variables. The state-space of the proposed model includes artificial latent variables, in addition to observed variables that can be fitted to a…
The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…
In this work we revisit a classical problem of traveling waves in a damped Frenkel-Kontorova lattice driven by a constant external force. We compute these solutions as fixed points of a nonlinear map and obtain the corresponding kinetic…
In this paper we present an individual-based mechanical model that describes the dynamics of two contiguous cell populations with different proliferative and mechanical characteristics. An off-lattice modelling approach is considered…
The aim of the article is to study the stability of a non-local kinetic model proposed by Loy and Preziosi (2019a). We split the population in two subgroups and perform a linear stability analysis. We show that pattern formation results…
A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…
Many cell types display random motility on two-dimensional substrates, but crawl persistently in a single direction when confined in a microchannel or on an adhesive micropattern. Does this imply that the motility mechanism of confined…
Suspensions of swimming micro-organisms provide examples of coordinated active dynamics. That has stimulated the study of a phenomenological theory combining synchronization and polar order in active matter. Here, we consider another…
In this work we describe a hyperbolic model with cell-cell repulsion with a dynamics in the population of cells. More precisely, we consider a population of cells producing a field (which we call "pressure") which induces a motion of the…
We perform stability analysis of a kinetic bacterial chemotaxis model of bacterial self-organization, assuming that bacteria respond sharply to chemical signals. The resulting discontinuous tumbling kernel represents the key challenge for…
We study the shape stability of disks moving in an external Laplacian field in two dimensions. The problem is motivated by the motion of ionization fronts in streamer-type electric breakdown. It is mathematically equivalent to the motion of…