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Recent emergence of next-generation DNA sequencing technology has enabled acquisition of genetic information at unprecedented scales. In order to determine the genetic blueprint of an organism, sequencing platforms typically employ…

Genomics · Quantitative Biology 2015-06-19 Xiaohu Shen , Manohar Shamaiah , Haris Vikalo

Deploying deep neural networks on mobile devices is increasingly important but remains challenging due to limited computing resources. On the other hand, their unified memory architecture and narrower gap between CPU and GPU performance…

Machine Learning · Computer Science 2026-02-20 Zhuojin Li , Marco Paolieri , Leana Golubchik

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Efficient and consistent string processing is critical in the exponentially growing genomic data era. Locally Consistent Parsing (LCP) addresses this need by partitioning an input genome string into short, exactly matching substrings (e.g.,…

Graph neural networks (GNNs) are powerful tools for learning from graph data and are widely used in various applications such as social network recommendation, fraud detection, and graph search. The graphs in these applications are…

Machine Learning · Computer Science 2021-06-14 Jialin Dong , Da Zheng , Lin F. Yang , Geroge Karypis

The Exact Set Similarity Join problem aims to find all similar sets between two collections of sets, with respect to a threshold and a similarity function such as overlap, Jaccard, dice or cosine. The naive approach verifies all pairs of…

Databases · Computer Science 2017-11-21 Edans F. O. Sandes , George Teodoro , Alba C. M. A. Melo

In the last decade a number of algorithms and associated software have been developed to align next generation sequencing (NGS) reads with relevant reference genomes. The accuracy of these programs may vary significantly, especially when…

Filters approximately store a set of items while trading off accuracy for space-efficiency and can address the limited memory on accelerators, such as GPUs. However, there is a lack of high-performance and feature-rich GPU filters as most…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-12-20 Hunter McCoy , Steven Hofmeyr , Katherine Yelick , Prashant Pandey

Bloom filters are a fundamental data structure for approximate membership queries, with applications ranging from data analytics to databases and genomics. Several variants have been proposed to accommodate parallel architectures. GPUs,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-18 Daniel Jünger , Kevin Kristensen , Yunsong Wang , Xiangyao Yu , Bertil Schmidt

An efficient error reconciliation scheme is important for post-processing of quantum key distribution (QKD). Recently, a multi-matrix low-density parity-check codes based reconciliation algorithm which can provide remarkable perspectives…

Quantum Physics · Physics 2020-01-23 Yu Guo , Chaohui Gao , Dong Jiang , Lijun Chen

Recent research on vision backbone architectures has predominantly focused on optimizing efficiency for hardware platforms with high parallel processing capabilities. This category increasingly includes embedded systems such as mobile…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Moritz Nottebaum , Matteo Dunnhofer , Christian Micheloni

Graphics Processing Units (GPUs) were once used solely for graphical computation tasks but with the increase in the use of machine learning applications, the use of GPUs to perform general-purpose computing has increased in the last few…

Hardware Architecture · Computer Science 2021-02-16 Asim Ikram , Muhammad Awais Ali , Mirza Omer Beg

Genome analysis fundamentally starts with a process known as read mapping, where sequenced fragments of an organism's genome are compared against a reference genome. Read mapping is currently a major bottleneck in the entire genome analysis…

Hardware Architecture · Computer Science 2020-10-29 Mohammed Alser , Zülal Bingöl , Damla Senol Cali , Jeremie Kim , Saugata Ghose , Can Alkan , Onur Mutlu

De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk

Gaussian Process Regression (GPR) is an important type of supervised machine learning model with inherent uncertainty measure in its predictions. We propose a new framework, nuGPR, to address the well-known challenge of high computation…

Machine Learning · Computer Science 2025-10-15 Ziqi Zhao , Vivek Sarin

Sequence alignment is one of the oldest and the most famous problems in bioinformatics. Even after 45 years, for one reason or another, this problem is still actual; current solutions are trade-offs between execution time, memory…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-04-23 Matija Korpar , Mile Sikic

With small-scale quantum processors transitioning from experimental physics labs to industrial products, these processors allow us to efficiently compute important algorithms in various fields. In this paper, we propose a quantum algorithm…

Quantum Physics · Physics 2020-05-22 Aritra Sarkar , Zaid Al-Ars , Carmen G. Almudever , Koen Bertels

Set intersection is the core in a variety of problems, e.g. frequent itemset mining and sparse boolean matrix multiplication. It is well-known that large speed gains can, for some computational problems, be obtained by using a graphics…

Data Structures and Algorithms · Computer Science 2011-02-07 Rasmus Resen Amossen , Rasmus Pagh

This paper presents a novel nearest neighbor search algorithm achieving TPU (Google Tensor Processing Unit) peak performance, outperforming state-of-the-art GPU algorithms with similar level of recall. The design of the proposed algorithm…

Performance · Computer Science 2022-07-01 Felix Chern , Blake Hechtman , Andy Davis , Ruiqi Guo , David Majnemer , Sanjiv Kumar

In this paper we introduce a novel parallel pipeline for fast and accurate mapping of RNA sequences on servers equipped with multicore processors. Our software, named HPG-Aligner, leverages the speed of the Burrows-Wheeler Transform to map…

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