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Fast 3D data analysis and steering of a tomographic experiment by changing environmental conditions or acquisition parameters require fast, close to real-time, 3D reconstruction of large data volumes. Here we present a performance-optimized…

Data Analysis, Statistics and Probability · Physics 2022-11-10 Viktor Nikitin

Efficiently finding subgraph embeddings in large graphs is crucial for many application areas like biology and social network analysis. Set intersections are the predominant and most challenging aspect of current join-based subgraph query…

Databases · Computer Science 2024-02-28 Jonas Dann , Tobias Götz , Daniel Ritter , Jana Giceva , Holger Fröning

Pyrosequencing is among the emerging sequencing techniques, capable of generating upto 100,000 overlapping reads in a single run. This technique is much faster and cheaper than the existing state of the art sequencing technique such as…

Genomics · Quantitative Biology 2016-09-08 Fahad Saeed , Ashfaq Khokhar , Osvaldo Zagordi , Niko Beerenwinkel

Despite the recent advances in model compression techniques for deep neural networks, deploying such models on ultra-low-power embedded devices still proves challenging. In particular, quantization schemes for Gated Recurrent Units (GRU)…

Machine Learning · Computer Science 2024-03-12 Riccardo Miccini , Alessandro Cerioli , Clément Laroche , Tobias Piechowiak , Jens Sparsø , Luca Pezzarossa

Advances in DNA sequencing technology have stimulated the development of algorithms and tools for processing very large collections of short strings (reads). Short-read alignment and assembly are among the most well-studied problems. Many…

Genomics · Quantitative Biology 2014-01-30 Chi-Man Liu , Ruibang Luo , Tak-Wah Lam

Genetic Programming (GP), an evolutionary learning technique, has multiple applications in machine learning such as curve fitting, data modelling, feature selection, classification etc. GP has several inherent parallel steps, making it an…

Neural and Evolutionary Computing · Computer Science 2021-10-22 Vimarsh Sathia , Venkataramana Ganesh , Shankara Rao Thejaswi Nanditale

Parallel processing of information plays a critical role in accelerating computation. This includes quantum computers, where parallel processing of quantum information will play a critical role in practical quantum advantage. Here, we…

The challenge of mapping AI architectures to GPU hardware is creating a critical bottleneck in AI progress. Despite substantial efforts, hand-written custom kernels fail to meet their theoretical performance thresholds, even on…

Machine Learning · Computer Science 2024-10-29 Benjamin F. Spector , Simran Arora , Aaryan Singhal , Daniel Y. Fu , Christopher Ré

The recent trend of using Graphics Processing Units (GPU's) for high performance computations is driven by the high ratio of price performance for these units, complemented by their cost effectiveness. At first glance, computational fluid…

Computational Engineering, Finance, and Science · Computer Science 2018-02-13 Kiril S. Shterev

Geometric Semantic Genetic Programming (GSGP) is a state-of-the-art machine learning method based on evolutionary computation. GSGP performs search operations directly at the level of program semantics, which can be done more efficiently…

Neural and Evolutionary Computing · Computer Science 2021-06-09 Leonardo Trujillo , Jose Manuel Muñoz Contreras , Daniel E Hernandez , Mauro Castelli , Juan J Tapia

Background: Identifying all possible mapping locations of next-generation sequencing (NGS) reads is highly essential in several applications such as prediction of genomic variants or protein binding motifs located in repeat regions, isoform…

Genomics · Quantitative Biology 2020-03-25 Ngoc Hieu Tran , Xin Chen

The task of understanding and interpreting the complex information encoded within genomic sequences remains a grand challenge in biological research and clinical applications. In this context, recent advancements in large language model…

Genomics · Quantitative Biology 2024-09-25 Qihang Zhao , Chi Zhang , Weixiong Zhang

We present a new approach for efficient approximate nearest neighbor (ANN) search in high dimensional spaces, extending the idea of Product Quantization. We propose a two-level product and vector quantization tree that reduces the number of…

Computer Vision and Pattern Recognition · Computer Science 2017-02-21 Patrick Wieschollek , Oliver Wang , Alexander Sorkine-Hornung , Hendrik P. A. Lensch

The recommendation system is a software system to predict customers' unknown preferences from known preferences. In the recommendation system, customers' preferences are encoded into vectors, and finding the nearest vectors to each vector…

Information Retrieval · Computer Science 2010-07-16 Kimikazu Kato , Tikara Hosino

Graph Pattern Mining (GPM) extracts higher-order information in a large graph by searching for small patterns of interest. GPM applications are computationally expensive, and thus attractive for GPU acceleration. Unfortunately, due to the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-28 Xuhao Chen , Arvind

This paper focuses on the alignment of flow matching models with human preferences. A promising way is fine-tuning by directly backpropagating reward gradients through the differentiable generation process of flow matching. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Zhanhao Liang , Tao Yang , Jie Wu , Chengjian Feng , Liang Zheng

Genome-to-genome comparisons require designating anchor points, which are given by Maximum Exact Matches (MEMs) between their sequences. For large genomes this is a challenging problem and the performance of existing solutions, even in…

Data Structures and Algorithms · Computer Science 2018-05-24 Szymon Grabowski , Wojciech Bieniecki

Analysis of DNA samples is an important step in forensics, and the speed of analysis can impact investigations. Comparison of DNA sequences is based on the analysis of short tandem repeats (STRs), which are short DNA sequences of 2-5 base…

Performance · Computer Science 2018-03-07 Siddharth Samsi , Brian Helfer , Jeremy Kepner , Albert Reuther , Darrell O. Ricke

Partitioning graphs into blocks of roughly equal size such that few edges run between blocks is a frequently needed operation in processing graphs. Recently, size, variety, and structural complexity of these networks has grown dramatically.…

Data Structures and Algorithms · Computer Science 2018-10-16 Yaroslav Akhremtsev , Peter Sanders , Christian Schulz

Top-k selection, which identifies the largest or smallest k elements from a data set, is a fundamental operation in data-intensive domains such as databases and deep learning, so its scalability and efficiency are critical for these…

Data Structures and Algorithms · Computer Science 2025-01-28 Yifei Li , Bole Zhou , Jiejing Zhang , Xuechao Wei , Yinghan Li , Yingda Chen
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