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Motivation: Seed location filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. State-of-the-art read…

Structural parameters are normally extracted from observed galaxies by fitting analytic light profiles to the observations. Obtaining accurate fits to high-resolution images is a computationally expensive task, requiring many model…

Instrumentation and Methods for Astrophysics · Physics 2015-03-17 Benjamin R. Barsdell , David G. Barnes , Christopher J. Fluke

The high degree of parallelism and relatively complicated synchronization mechanisms in GPUs make writing correct kernels difficult. Data races pose one such concurrency correctness challenge, and therefore, effective methods of detecting…

Programming Languages · Computer Science 2021-11-25 Sagnik Dey , Mayant Mukul , Parth Sharma , Swarnendu Biswas

Computation of bounding boxes is a fundamental problem in high performance rendering, as it is an input to visibility culling and binning operations. In a scene description structured as a tree, clip nodes and blend nodes entail…

Graphics · Computer Science 2022-05-25 Raph Levien

Motivation: A pan-genome graph represents a collection of genomes and encodes sequence variations between them. It is a powerful data structure for studying multiple similar genomes. Sequence-to-graph alignment is an essential step for the…

Genomics · Quantitative Biology 2022-06-29 Haowen Zhang , Shiqi Wu , Srinivas Aluru , Heng Li

The IEEE 754-2008 standard recommends the correct rounding of some elementary functions. This requires to solve the Table Maker's Dilemma which implies a huge amount of CPU computation time. We consider in this paper accelerating such…

Mathematical Software · Computer Science 2013-06-06 Pierre Fortin , Mourad Gouicem , Stef Graillat

In recent years graphical processing units (GPUs) have become a powerful tool in scientific computing. Their potential to speed up highly parallel applications brings the power of high performance computing to a wider range of users.…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-26 Uldis Locans , Andreas Adelmann , Andreas Suter , Jannis Fischer , Werner Lustermann , Gunther Dissertori , Qiulin Wang

Motivation: Seed filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. Read mappers 1) quickly…

The self-join finds all objects in a dataset that are within a search distance, epsilon, of each other; therefore, the self-join is a building block of many algorithms. We advance a GPU-accelerated self-join algorithm targeted towards high…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Michael Gowanlock , Ben Karsin

We investigate the problem of exact set similarity joins using a co-process CPU-GPU scheme. The state-of-the-art CPU solutions split the wok in two main phases. First, filtering and index building takes place to reduce the candidate sets to…

Databases · Computer Science 2018-12-24 Christos Bellas , Anastasios Gounaris

Read mapping is a fundamental, yet computationally-expensive step in many genomics applications. It is used to identify potential matches and differences between fragments (called reads) of a sequenced genome and an already known genome…

The continued growth of the computational capability of throughput processors has made throughput processors the platform of choice for a wide variety of high performance computing applications. Graphics Processing Units (GPUs) are a prime…

Hardware Architecture · Computer Science 2018-05-01 Rachata Ausavarungnirun

Subgraph matching is a core operation in graph analytics, supporting a broad spectrum of applications from social network analysis to bioinformatics. Recent GPU-based approaches accelerate subgraph matching by leveraging parallelism but…

Databases · Computer Science 2026-04-14 Weitian Chen , Shixuan Sun , Cheng Chen , Yongmin Hu , Yingqian Hu , Minyi Guo

This research proposes a practical method for detecting featureless objects by using image alignment approach with a robust similarity measure in industrial applications. This similarity measure is robust against occlusion, illumination…

Computer Vision and Pattern Recognition · Computer Science 2021-12-13 Trung-Son Le , Chyi-Yeu Lin

A critical step of genome sequence analysis is the mapping of sequenced DNA fragments (i.e., reads) collected from an individual to a known linear reference genome sequence (i.e., sequence-to-sequence mapping). Recent works replace the…

Efficient inference on GPUs using large language models remains challenging due to memory bandwidth limitations, particularly during data transfers between High Bandwidth Memory (HBM) and SRAM in attention computations. Approximate…

Machine Learning · Computer Science 2025-06-06 Nirav Koley , Prajwal Singhania , Abhinav Bhatele

DNA sequencing is the physical/biochemical process of identifying the location of the four bases (Adenine, Guanine, Cytosine, Thymine) in a DNA strand. As semiconductor technology revolutionized computing, modern DNA sequencing technology…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-06 S. Karen Khatamifard , Zamshed Chowdhury , Nakul Pande , Meisam Razaviyayn , Chris Kim , Ulya R. Karpuzcu

It is often difficult to write code that you can ensure will be executed in the right order when programing for parallel compute tasks. Due to the way that today's parallel compute hardware, primarily Graphical Processing Units (GPUs),…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-13 Andrew Osterhout , Ganesh Gopalakrishnan

The accuracy of large language models (LLMs) improves with increasing model size, but increasing model complexity also poses significant challenges to training stability. Periodic checkpointing is a key mechanism for fault recovery and is…

Operating Systems · Computer Science 2025-11-11 Keyao Zhang , Yiquan Chen , Zhuo Hu , Wenhai Lin , Jiexiong Xu , Wenzhi Chen

Process mapping asks to assign vertices of a task graph to processing elements of a supercomputer such that the computational workload is balanced while the communication cost is minimized. Motivated by the recent success of GPU-based graph…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-16 Petr Samoldekin , Christian Schulz , Henning Woydt