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We present HSIM: a dedicated pipeline for simulating observations with the HARMONI integral field spectrograph on the European Extremely Large Telescope. HSIM takes high spectral and spatial resolution input data-cubes, encoding physical…

Instrumentation and Methods for Astrophysics · Physics 2015-09-30 S. Zieleniewski , N. Thatte , S. Kendrew , R. C. W. Houghton , A. M. Swinbank , M. Tecza , F. Clarke , T. Fusco

We report a method for fabricating nanogaps directly with electron beam lithography (EBL). The primary resolution-limit of EBL, electron back-scattering, is reduced dramatically by using a thin-film as a substrate. We show that this…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 Michael D. Fischbein , Marija Drndic

Low-electron-dose observation is indispensable for observing various samples using a transmission electron microscope; consequently, image processing has been used to improve transmission electron microscopy (TEM) images. To apply such…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Hiroyasu Katsuno , Yuki Kimura , Tomoya Yamazaki , Ichigaku Takigawa

Aberration-corrected Scanning Transmission Electron Microscopy (STEM) has become an essential tool in understanding materials at the atomic scale. However, tuning the aberration corrector to produce a sub-{\AA}ngstr\"om probe is a complex…

We present a new analysis method for atomic resolution four-dimensional scanning transmission electron microscopy (4D-STEM, in which a diffraction pattern is collected at each point of a raster scan of a focused electron beam across the…

Instrumentation and Detectors · Physics 2025-08-11 Yining Xie , Eoin Moynihan , Marin Alexe , Louis Piper , Ana Sanchez , Richard Beanland

Simulation of atomic resolution image formation in scanning transmission electron microscopy can require significant computation times using traditional methods. A recently developed method, termed plane-wave reciprocal-space interpolated…

Computational Physics · Physics 2017-07-07 Alan Pryor , Colin Ophus , Jianwei Miao

We theoretically develop and experimentally demonstrate a holographic method for imaging cold atoms at the diffraction and photon shot noise limits. Aided by a double point source reference field, a simple iterative algorithm robustly…

Atomic Physics · Physics 2015-06-18 J. P. Sobol , Saijun Wu

High-throughput analysis of multidimensional transmission electron microscopy (TEM) datasets remains a significant challenge, limiting the broader impact on strategic materials research. Conventional workflows typically involve sequential,…

Materials Science · Physics 2025-07-16 Arda Genc , Ravit Silverstein

We propose a novel hue-correction scheme for multi-exposure image fusion (MEF). Various MEF methods have so far been studied to generate higher-quality images. However, there are few MEF methods considering hue distortion unlike other…

Image and Video Processing · Electrical Eng. & Systems 2020-12-30 Kouki Seo , Chihiro Go , Yuma Kinoshita , Hitoshi Kiya

Although defocus can be used to generate partial phase contrast in transmission electron microscope images, cryo-electron microscopy (cryo-EM) can be further improved by the development of phase plates which increase contrast by applying a…

Quantitative Methods · Quantitative Biology 2024-03-14 Jeremy J. Axelrod , Jessie T. Zhang , Petar N. Petrov , Robert M. Glaeser , Holger Mueller

A detailed analysis of ptychography for 3D phase reconstructions of thick specimens is performed. We introduce multi-focus ptychography, which incorporates a 4D-STEM defocus series to enhance the quality of 3D reconstructions along the beam…

The characteristics of an x-ray spectrum can greatly influence imaging and related tasks. In practice, due to the pile-up effect of the detector, it's difficult to directly measure the spectrum of a CT scanner using an energy resolved…

Medical Physics · Physics 2015-03-09 Wei Zhao , Kai Niu , Sebastian Schafer , Kevin Royalty

Accurate molecular imaging via high-order harmonic generation relies on comparing the harmonic emission from a molecule and an adequate reference system. However, an ideal reference atom with the same ionization properties as the molecule…

Atomic Physics · Physics 2015-05-28 Elmar V. van der Zwan , Manfred Lein

The concept of compressive sensing was recently proposed to significantly reduce the electron dose in scanning transmission electron microscopy (STEM) while still maintaining the main features in the image. Here, an experimental setup based…

Instrumentation and Detectors · Physics 2016-03-23 Armand Béché , Bart Goris , Bert Freitag , Jo Verbeeck

Scanning Electron Microscopy (SEM) is indispensable in modern materials science, enabling high-resolution imaging across a wide range of structural, chemical, and functional investigations. However, SEM imaging remains constrained by…

Scanning transmission electron microscopy (STEM) is an extremely versatile method for studying materials on the atomic scale. Many STEM experiments are supported or validated with electron scattering simulations. However, using the…

Computational studies of electrochemical interfaces based on density-functional theory (DFT) play an increasingly important role in present research on electrochemical processes for energy conversion and storage. The homogeneous background…

Materials Science · Physics 2022-04-26 Arthur Hagopian , Marie-Liesse Doublet , Jean-Sébastien Filhol , Tobias Binninger

Modern cameras have limited dynamic ranges and often produce images with saturated or dark regions using a single exposure. Although the problem could be addressed by taking multiple images with different exposures, exposure fusion methods…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Sheng-Yeh Chen , Yung-Yu Chuang

High-throughput 2D and 3D scanning electron microscopy, which relies on automation and dependable control algorithms, requires high image quality with minimal human intervention. Classical focus and astigmatism correction algorithms attempt…

Instrumentation and Detectors · Physics 2023-05-10 Philipp Johannes Schubert , Rangoli Saxena , Joergen Kornfeld

Electron microscopy is a powerful tool for studying the properties of materials down to their atomic structure. In many cases, the quantitative interpretation of images requires simulations based on atomistic structure models. These…

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