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To enhance the domain-specific capabilities of large language models, continued pre-training on a domain-specific corpus is a prevalent method. Recent work demonstrates that adapting models using reading comprehension data formatted by…

Computation and Language · Computer Science 2024-01-19 Ting Jiang , Shaohan Huang , Shengyue Luo , Zihan Zhang , Haizhen Huang , Furu Wei , Weiwei Deng , Feng Sun , Qi Zhang , Deqing Wang , Fuzhen Zhuang

With the exponential increase in online scientific literature, identifying reliable domain-specific data has become increasingly important but also very challenging. Manual data collection and filtering for domain-specific scientific…

Information Retrieval · Computer Science 2026-03-10 Nikita Gautam , Doina Caragea , Ignacio Ciampitti , Federico Gomez

Computational phenotyping is a central informatics activity with resulting cohorts supporting a wide variety of applications. However, it is time-intensive because of manual data review and limited automation. Since LLMs have demonstrated…

Quantitative Methods · Quantitative Biology 2025-08-18 Sarah Pungitore , Shashank Yadav , Molly Douglas , Jarrod Mosier , Vignesh Subbian

Large language models (LLMs) have shown impressive performance on general-purpose tasks, yet adapting them to specific domains remains challenging due to the scarcity of high-quality domain data. Existing data synthesis tools often struggle…

Computation and Language · Computer Science 2025-07-08 Ziyang Miao , Qiyu Sun , Jingyuan Wang , Yuchen Gong , Yaowei Zheng , Shiqi Li , Richong Zhang

This paper presents an open-source enforcement learning toolkit named CytonRL (https://github.com/arthurxlw/cytonRL). The toolkit implements four recent advanced deep Q-learning algorithms from scratch using C++ and NVIDIA's GPU-accelerated…

Machine Learning · Computer Science 2018-04-18 Xiaolin Wang

Lagrange coded computation (LCC) is essential to solving problems about matrix polynomials in a coded distributed fashion; nevertheless, it can only solve the problems that are representable as matrix polynomials. In this paper, we propose…

Information Theory · Computer Science 2022-05-23 Navneet Agrawal , Yuqin Qiu , Matthias Frey , Igor Bjelakovic , Setareh Maghsudi , Slawomir Stanczak , Jingge Zhu

Code generation models based on large language models (LLMs) have gained wide adoption, but challenges remain in ensuring safety, accuracy, and controllability, especially for complex tasks. Existing methods often lack dynamic integration…

Software Engineering · Computer Science 2025-10-13 Aofan Liu , Haoxuan Li , Bin Wang , Ao Yang , Hui Li

Repository-level coding agents must first localize the files and symbols relevant to a task; failures at this stage can cascade across downstream objectives ranging from patch generation to test writing and codebase question answering.…

Information Retrieval · Computer Science 2026-05-19 Yuntong Hu , Tongli Su , Liang Zhao , Bowen Zhu , Hasibul Haque

Next-generation sequencing (NGS) technologies have enabled affordable sequencing of billions of short DNA fragments at high throughput, paving the way for population-scale genomics. Genomics data analytics at this scale requires overcoming…

Databases · Computer Science 2019-10-11 Darryl Ho , Jialin Ding , Sanchit Misra , Nesime Tatbul , Vikram Nathan , Vasimuddin Md , Tim Kraska

Edge intelligence delivers low-latency inference, yet most edge analytics remain hard-coded and must be redeployed as conditions change. When data patterns shift or new questions arise, engineers often need to write new scripts and push…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Chinmaya Kumar Dehury , Siddharth Singh Kushwaha , Qiyang Zhang , Alaa Saleh , Praveen Kumar Donta

De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk

Acquiring labelled training data remains a costly task in real world machine learning projects to meet quantity and quality requirements. Recently Large Language Models (LLMs), notably GPT-4, have shown great promises in labelling data with…

Computation and Language · Computer Science 2025-01-22 Thomas Walshe , Sae Young Moon , Chunyang Xiao , Yawwani Gunawardana , Fran Silavong

A major driver behind the success of modern machine learning algorithms has been their ability to process ever-larger amounts of data. As a result, the use of distributed systems in both research and production has become increasingly…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-10 Fan Yang , Gabriel Barth-Maron , Piotr Stańczyk , Matthew Hoffman , Siqi Liu , Manuel Kroiss , Aedan Pope , Alban Rrustemi

DNA barcoding has emerged as a cost-effective approach for species identification. However, the scarcity of tools used for searching the booming reference database becomes an obstacle, currently with BLAST as the only practical choice.…

Populations and Evolution · Quantitative Biology 2014-07-15 Long Fan , Ka Hou Chu

Large Language Models (LLMs) have recently demonstrated remarkable performance in various Natural Language Processing (NLP) applications, such as sentiment analysis, content generation, and personalized recommendations. Despite their…

Computation and Language · Computer Science 2024-12-10 Mahaman Sanoussi Yahaya Alassan , Jessica López Espejel , Merieme Bouhandi , Walid Dahhane , El Hassane Ettifouri

Huge numbers of short reads are being generated for mapping back to the genome to discover the frequency of transcripts, miRNAs, DNAase hypersensitive sites, FAIRE regions, nucleosome occupancy, etc. Since these reads are typically short…

Genomics · Quantitative Biology 2009-12-31 Peter J. Waddell , Timothy Herston

Large language models (LLMs) often incorporate multiple text chunks in their inputs to provide the necessary contexts. To speed up the prefill of the long LLM inputs, one can pre-compute the KV cache of a text and re-use the KV cache when…

Machine Learning · Computer Science 2025-04-07 Jiayi Yao , Hanchen Li , Yuhan Liu , Siddhant Ray , Yihua Cheng , Qizheng Zhang , Kuntai Du , Shan Lu , Junchen Jiang

The understanding of large-scale scientific software poses significant challenges due to its diverse codebase, extensive code length, and target computing architectures. The emergence of generative AI, specifically large language models…

Software Engineering · Computer Science 2024-03-19 Kareem Shaik , Dali Wang , Weijian Zheng , Qinglei Cao , Heng Fan , Peter Schwartz , Yunhe Feng

Background: Leaking sensitive information - such as API keys, tokens, and credentials - in source code remains a persistent security threat. Traditional regex and entropy-based tools often generate high false positives due to limited…

Software Engineering · Computer Science 2025-07-29 Md Nafiu Rahman , Sadif Ahmed , Zahin Wahab , S M Sohan , Rifat Shahriyar

As mobile robot capabilities improve and deployment times increase, tools to analyze the growing volume of data are becoming necessary. Current state-of-the-art logging, playback, and exploration systems are insufficient for practitioners…

Robotics · Computer Science 2020-08-03 Samer B. Nashed