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Grey literature is essential to software engineering research as it captures practices and decisions that rarely appear in academic venues. However, collecting and assessing it at scale remains difficult because of their heterogeneous…

The emergence of foundational models and generative artificial intelligence (GenAI) is poised to transform productivity in scientific computing, especially in code development, refactoring, and translating from one programming language to…

Software Engineering · Computer Science 2025-11-10 Akash Dhruv , Anshu Dubey

Genome sequence alignment is the core of many biological applications. The advancement of sequencing technologies produces a tremendous amount of data, making sequence alignment a critical bottleneck in bioinformatics analysis. The existing…

Hardware Architecture · Computer Science 2023-01-26 Weihong Xu , Saransh Gupta , Niema Moshiri , Tajana Rosing

We here present SIMLR (Single-cell Interpretation via Multi-kernel LeaRning), an open-source tool that implements a novel framework to learn a sample-to-sample similarity measure from expression data observed for heterogenous samples. SIMLR…

Genomics · Quantitative Biology 2018-01-22 Bo Wang , Daniele Ramazzotti , Luca De Sano , Junjie Zhu , Emma Pierson , Serafim Batzoglou

Compilers are complex, and significant effort has been expended on testing them. Techniques such as random program generation and differential testing have proved highly effective and have uncovered thousands of bugs in production…

Software Engineering · Computer Science 2025-01-03 Davide Italiano , Chris Cummins

Large Language Models (LLMs) have demonstrated remarkable capabilities across various domains, with code generation emerging as a key area of focus. While numerous benchmarks have been proposed to evaluate their code generation abilities,…

We demonstrate LLARS (LLM Assisted Research System), an open-source platform that bridges the gap between domain experts and developers for building LLM-based systems. It integrates three tightly connected modules into an end-to-end…

Artificial Intelligence · Computer Science 2026-05-12 Philipp Steigerwald , Mara Stieler , Jennifer Burghardt , Eric Rudolph , Jens Albrecht

The third-generation long reads sequencing technologies, such as PacBio and Nanopore, have great advantages over second-generation Illumina sequencing in de novo assembly studies. However, due to the inherent low base accuracy,…

Genomics · Quantitative Biology 2020-03-27 Hengchao Wang , Bo Liu , Yan Zhang , Fan Jiang , Yuwei Ren , Lijuan Yin , Hangwei Liu , Sen Wang , Wei Fan

Retrieval-augmented generation (RAG) has been widely adopted to augment large language models (LLMs) with external knowledge for knowledge-intensive tasks. However, its effectiveness is often undermined by the presence of noisy (i.e.,…

Information Retrieval · Computer Science 2025-10-09 Minghao Tang , Shiyu Ni , Jiafeng Guo , Keping Bi

Regular expressions (regexes) are foundational to modern computing for critical tasks like input validation and data parsing, yet their ubiquity exposes systems to regular expression denial of service (ReDoS), a vulnerability requiring…

Artificial Intelligence · Computer Science 2025-10-13 Sicheol Sung , Joonghyuk Hahn , Yo-Sub Han

Reverse engineering and rapid prototyping of computer-aided design (CAD) models from 3D scans, sketches, or simple text prompts are vital in industrial product design. However, recent advances in geometric deep learning techniques lack a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Pritham Kumar Jena , Bhavika Baburaj , Tushar Anand , Vedant Dutta , Vineeth Ulavala , Sk Aziz Ali

Graphs, consisting of vertices and edges, are vital for representing complex relationships in fields like social networks, finance, and blockchain. Visualizing these graphs helps analysts identify structural patterns, with readability…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-18 Sanggeon Yun

Program repair techniques offer cost-saving benefits for debugging within software development and programming education scenarios. With the proven effectiveness of Large Language Models (LLMs) in code-related tasks, researchers have…

Software Engineering · Computer Science 2024-07-09 Boyang Yang , Haoye Tian , Weiguo Pian , Haoran Yu , Haitao Wang , Jacques Klein , Tegawendé F. Bissyandé , Shunfu Jin

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Dmitriy Dligach , Timothy A. Miller , Samantha Barr , Yanjun Gao , Matthew Churpek , Anoop Mayampurath , Majid Afshar

Deep Reinforcement Learning (RL) can yield capable agents and control policies in several domains but is commonly plagued by prohibitively long training times. Additionally, in the case of continuous control problems, the applicability of…

Machine Learning · Computer Science 2024-11-20 Jonas Eschmann , Dario Albani , Giuseppe Loianno

In this paper, we consider a mixed-prompt scenario for a large language model (LLM) inference serving system that supports diverse applications with both short prompts and long prompts and heterogeneous SLOs for iteration time. To improve…

Computation and Language · Computer Science 2025-03-19 Haiying Shen , Tanmoy Sen

Reinforcement learning (RL) algorithms involve the deep nesting of highly irregular computation patterns, each of which typically exhibits opportunities for distributed computation. We argue for distributing RL components in a composable…

Artificial Intelligence · Computer Science 2018-07-02 Eric Liang , Richard Liaw , Philipp Moritz , Robert Nishihara , Roy Fox , Ken Goldberg , Joseph E. Gonzalez , Michael I. Jordan , Ion Stoica

Retrieval-Augmented Generation (RAG) systems enhance large language models (LLMs) by integrating external knowledge sources, enabling more accurate and contextually relevant responses tailored to user needs. However, existing RAG systems…

Information Retrieval · Computer Science 2025-04-29 Zirui Guo , Lianghao Xia , Yanhua Yu , Tu Ao , Chao Huang

Generative AI technology based on Large Language Models (LLM) has been developed and applied to assist or automatically generate program codes. In this paper, we evaluate the capability of existing general LLMs for Basic Linear Algebra…

Machine Learning · Computer Science 2025-07-08 Daichi Mukunoki , Shun-ichiro Hayashi , Tetsuya Hoshino , Takahiro Katagiri