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This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

Populations and Evolution · Quantitative Biology 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

The characterization of plasticity, robustness, and evolvability, an important issue in biology, is studied in terms of phenotypic fluctuations. By numerically evolving gene regulatory networks, the proportionality between the phenotypic…

Populations and Evolution · Quantitative Biology 2015-06-15 Kunihiko Kaneko

Comparing allele frequencies among populations that differ in environment has long been a tool for detecting loci involved in local adaptation. However, such analyses are complicated by an imperfect knowledge of population allele…

Populations and Evolution · Quantitative Biology 2012-09-17 Torsten Günther , Graham Coop

Deep Learning is considered to be a quite young in the area of machine learning research, found its effectiveness in dealing complex yet high dimensional dataset that includes but limited to images, text and speech etc. with multiple levels…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Mrutyunjaya Panda

Cryptic genetic sequences have attenuated effects on phenotypes. In the classic view, relaxed selection allows cryptic genetic diversity to build up across individuals in a population, providing alleles that may later contribute to…

Populations and Evolution · Quantitative Biology 2013-05-23 Etienne Rajon , Joanna Masel

Why deep neural networks (DNNs) capable of overfitting often generalize well in practice is a mystery [#zhang2016understanding]. To find a potential mechanism, we focus on the study of implicit biases underlying the training process of…

Machine Learning · Computer Science 2019-11-04 Zhi-Qin John Xu , Yaoyu Zhang , Yanyang Xiao

Phylogenies are commonly used to represent the evolutionary relationships between species, and often these phylogenies are equipped with edge lengths that indicate degrees of evolutionary difference. Given such a phylogeny, a popular…

Populations and Evolution · Quantitative Biology 2025-02-12 Martin Frohn , Kerry Manson

Through the use of first name substitution experiments, prior research has demonstrated the tendency of social commonsense reasoning models to systematically exhibit social biases along the dimensions of race, ethnicity, and gender (An et…

Computation and Language · Computer Science 2023-05-29 Haozhe An , Rachel Rudinger

In the classic view introduced by R. A. Fisher, a quantitative trait is encoded by many loci with small, additive effects. Recent advances in QTL mapping have begun to elucidate the genetic architectures underlying vast numbers of…

Populations and Evolution · Quantitative Biology 2013-10-04 Etienne Rajon , Joshua B. Plotkin

We study the response of a quantitative trait to exponential directional selection in a finite haploid population at the genetic and the phenotypic level. We assume an infinite sites model, in which the number of new mutations per…

Populations and Evolution · Quantitative Biology 2024-04-10 Hannah Götsch , Reinhard Bürger

The relationship between sequences and secondary structures or shapes in RNA exhibits robust statistical properties summarized by three notions: (1) the notion of a typical shape (that among all sequences of fixed length certain shapes are…

Biological Physics · Physics 2009-10-31 Peter Schuster , Walter Fontana

In general, cellular phenotypes, as measured by concentrations of cellular components, involve large degrees of freedom. However, recent measurement has demonstrated that phenotypic changes resulting from adaptation and evolution in…

Populations and Evolution · Quantitative Biology 2020-03-04 Takuya U. Sato , Kunihiko Kaneko

How the neutral diversity is affected by selection and adaptation is investigated in an eco-evolutionary framework. In our model, we study a finite population in continuous time, where each individual is characterized by a trait under…

Probability · Mathematics 2019-08-15 Sylvain Billiard , Regis Ferriere , Sylvie Méléard , Viet Chi Tran

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any…

Methodology · Statistics 2011-11-16 Jianqing Fan , Xu Han , Weijie Gu

Intraspecific trait variation has been increasingly recognized as an important factor in determining species interaction and diversity. Eco-evolutionary models have studied the distribution of trait values within a population that changes…

Populations and Evolution · Quantitative Biology 2023-10-12 Zachary Jackson , BingKan Xue

Patterns provide a concise, syntactic way of describing a set of strings, but their expressive power comes at a price: a number of fundamental decision problems concerning (erasing) pattern languages, such as the membership problem and…

Formal Languages and Automata Theory · Computer Science 2019-05-21 Ziyuan Gao

This article reviews and evaluates models of network evolution based on the notion of structural diversity. We show that diversity is an underlying theme of three principles of network evolution: the preferential attachment model,…

Social and Information Networks · Computer Science 2020-09-22 Jérôme Kunegis

Static word embedding is still useful, particularly for context-unavailable tasks, because in the case of no context available, pre-trained language models often perform worse than static word embeddings. Although dimension is a key factor…

Computation and Language · Computer Science 2023-05-16 Lingfeng Shen , Haiyun Jiang , Lemao Liu , Ying Chen

Controlling the false discovery rate (FDR) is a popular approach to multiple testing, variable selection, and related problems of simultaneous inference. In many contemporary applications, models are not specified by discrete variables,…

Statistics Theory · Mathematics 2024-04-16 Mateo Díaz , Venkat Chandrasekaran

In this work we present a systematic mathematical approximation scheme that exposes the way that information, about the evolutionary forces of selection and random genetic drift, is encoded in gene-frequency trajectories. We determine…

Populations and Evolution · Quantitative Biology 2023-05-26 Konstantinos Mavreas , David Waxman
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