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In order to implement disease-specific interventions in young age groups, policy makers in low- and middle-income countries require timely and accurate estimates of age- and cause-specific child mortality. High quality data is not available…

In developing countries around the world, a multitude of infants continue to suffer and die from vaccine-preventable diseases, and malnutrition. Lamentably, the lack of any official identification documentation makes it exceedingly…

Computer Vision and Pattern Recognition · Computer Science 2019-04-03 Joshua J. Engelsma , Debayan Deb , Anil K. Jain , Prem S. Sudhish , Anjoo Bhatnager

We investigate the decline of infant mortality in 42 low and middle income countries (LMIC) using detailed micro data from 84 Demographic and Health Surveys. We estimate infant mortality risk for each infant in our data and develop a novel…

Applications · Statistics 2020-09-14 Antonio P. Ramos , Martin J. Flores , Leiwen Gao , Patrick Heuveline , Robert E. Weiss

Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have…

Computation · Statistics 2018-03-13 Richard J. Boys , Holly F. Ainsworth , Colin S. Gillespie

We consider birth-and-death processes of objects (animals) defined in ${\bf Z}^d$ having unit death rates and random birth rates. For animals with uniformly bounded diameter we establish conditions on the rate distribution under which the…

Probability · Mathematics 2007-05-23 Roberto Fernandez , Pablo A. Ferrari , Gustavo R. Guerberoff

It has been known for many years that small fractions of persister cells resist killing in many bacterial colony-antimicrobial confrontations. These persisters are not believed to be mutants. Rather it has been hypothesized that they are…

Cell Behavior · Quantitative Biology 2007-05-23 I. Klapper , P. Gilbert , B. P. Ayati , J. Dockery , P. S. Stewart

Demographic data and recent experiments verify earlier predictions that mortality has short (few percent of the life span) memory of the previous life history, may be significantly decreased, reset to its value at a much younger age, and…

Quantitative Methods · Quantitative Biology 2007-05-23 Mark Ya. Azbel'

Sedimentation in active fluids has come into focus due to the ubiquity of swimming micro-organisms in natural and industrial processes. Here, we investigate sedimentation dynamics of passive particles in a fluid as a function of bacteria E.…

Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and…

Cell Behavior · Quantitative Biology 2016-12-26 Indrani Bose , Mainak Pal

Living organisms have some common structures, chemical reactions and molecular structures. The organisms consist of cells with cell division, they have homochirality of protein and carbohydrate units, and metabolism, and genetics, and they…

Populations and Evolution · Quantitative Biology 2025-05-27 Søren Toxvaerd

The study considers the model of an abstract organism, called Arbitrary Oscillator (ArbO), which is capable of making decisions at each timed step. These decisions are 'critical' since, randomly, their outcome can be 'fatal' for ArbO, thus…

Physics and Society · Physics 2026-01-07 Giuseppe Alberti

Recent studies have shown that even in the absence of extrinsic stress, the morphologically symmetrically dividing model bacteria Escherichia coli do not generate offspring with equal reproductive fitness. Instead, daughter cells exhibit…

Populations and Evolution · Quantitative Biology 2020-01-01 Natasha Blitvić , Vicente I. Fernandez

Understanding historical datasets, such as the England and Wales infant mortality data, for local government districts can provide valuable insights into our changing society. Such analyses can prove challenging in practice, due to frequent…

Applications · Statistics 2026-01-23 Tessa Wilkie , Idris Eckley , Paul Fearnhead , Ian Gregory

Assuming the deleterious mutations in the Penna ageing model to affect mainly the young ages, we get an enhanced mortality at very young age, followed by a minimum of the mortality, and then the usual exponential increase of mortality with…

Populations and Evolution · Quantitative Biology 2007-08-28 D. Stauffer , S. Moss de Oliveira

Perinatal epidemiology often aims to evaluate exposures on infant outcomes. When the exposure affects the composition of people who give birth to live infants (e.g., by affecting fertility, behavior, or birth outcomes), this "live birth…

Methodology · Statistics 2024-01-23 Shalika Gupta , Laura B. Balzer , Moses R. Kamya , Diane V. Havlir , Maya L. Petersen

We studied the swimming of \textit{Escherichia coli} bacteria in the vicinity of the critical point in a solution of the non-ionic surfactant \chem{C_{12}E_{5}} in buffer solution. In phase contrast microscopy, each swimming cell produces a…

Soft Condensed Matter · Physics 2018-08-07 Nick Koumakis , Clémence Devailly , Wilson C. K. Poon

Objective: Cause-of-death distributions are important for prioritising interventions. We estimated proportions, risks, and numbers of deaths (with uncertainty) for programme-relevant causes of neonatal death for 194 countries for 2000-2013,…

Applications · Statistics 2014-11-17 Shefali Oza , Joy E Lawn , Daniel R Hogan , Colin Mathers , Simon Cousens

This paper aims to assess the effects of industrial pollution on infant mortality between the years 1850-1940 using full count decennial censuses. In this period, US economy experienced a tremendous rise in industrial activity with…

General Economics · Economics 2021-01-12 Nahid Tavassoli , Hamid Noghanibehambari , Farzaneh Noghani , Mostafa Toranji

How multicellular life forms evolved out from unicellular ones constitutes a major problem in our understanding of the evolution of our biosphere. A recent set of experiments involving yeast cell populations has shown that selection for…

Populations and Evolution · Quantitative Biology 2015-11-10 Salva Duran-Nebreda , Ricard V. Solé

Quantification of heritability is a fundamental desideratum in genetics, which allows an assessment of the contribution of additive genetic variation to the variability of a trait of interest. The traditional computational approaches for…

Applications · Statistics 2023-05-03 The Tien Mai , John A Lees , Rebecca A Gladstone , Jukka Corander