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Accurate prediction of anthropometric body composition variables, such as Appendicular Lean Mass (ALM), Body Fat Percentage (BFP), and Bone Mineral Density (BMD), is essential for early diagnosis of several chronic diseases. Currently,…

In this paper we present a new 3D segmentation approach for the vertebrae of the lower thoracic and the lumbar spine in spiral computed tomography datasets. We implemented a multi-step procedure. Its main components are deformable models,…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Andre Mastmeyer , Klaus Engelke , Sebastian Meller , Willi Kalender

We propose a 3D neural network with specific loss functions for quantitative computed tomography (QCT) noise reduction to compute micro-structural parameters such as tissue mineral density (TMD) and bone volume ratio (BV/TV) with…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Felix Thomsen , José M. Fuertes García , Manuel Lucena , Juan Pisula , Rodrigo de Luis García , Jan Broggrefe , Claudio Delrieux

Osteoporosis and osteopenia remain vastly underdiagnosed. Current clinical screening relies almost exclusively on dual-energy X-ray absorptiometry (DXA), which measures bone mineral density (BMD) but fails to capture the compositional…

Medical Physics · Physics 2025-10-29 Mohammad Hosseini , Sadia Afrin , Anthony Yosick , Emma Schenker , Hani Awad , Andrew J. Berger

Chest X-rays (CXRs) are commonly utilized as a low-dose modality for lung screening. Nonetheless, the efficacy of CXRs is somewhat impeded, given that approximately 75% of the lung area overlaps with bone, which in turn hampers the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Zhanghao Chen , Yifei Sun , Wenjian Qin , Ruiquan Ge , Cheng Pan , Wenming Deng , Zhou Liu , Wenwen Min , Ahmed Elazab , Xiang Wan , Changmiao Wang

Bone health studies are crucial in medical practice for the early detection and treatment of Osteopenia and Osteoporosis. Clinicians usually make a diagnosis based on densitometry (DEXA scans) and patient history. The applications of AI in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Alvaro Lopez Pellicer , Andre Mariucci , Plamen Angelov , Marwan Bukhari , Jemma G. Kerns

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Ayesha Siddiqua , Rakibul Hasan , Anichur Rahman , Abu Saleh Musa Miah

The segmentation of metastatic bone disease (MBD) in whole-body MRI (WB-MRI) is a challenging problem. Due to varying appearances and anatomical locations of lesions, ambiguous boundaries, and severe class imbalance, obtaining reliable…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Joris Wuts , Jakub Ceranka , Nicolas Michoux , Frédéric Lecouvet , Jef Vandemeulebroucke

Osteoporosis silently erodes skeletal integrity worldwide; however, early detection through imaging can prevent most fragility fractures. Artificial intelligence (AI) methods now mine routine Dual-energy X-ray Absorptiometry (DXA), X-ray,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-02 Abdul Rahman , Bumshik Lee

Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA), which quantifies areal bone mineral density but overlooks bone microarchitecture and surrounding soft tissues. High-resolution peripheral…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Mohseu Rashid Subah , Mohammed Abdul Gani Zilani , Thomas L. Nickolas , Matthew R. Allen , Stuart J. Warden , Rachel K. Surowiec

Bipolar Disorder (BD) is a psychiatric condition diagnosed by repetitive cycles of hypomania and depression. Since diagnosing BD relies on subjective behavioral assessments over a long period, a solid diagnosis based on objective criteria…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Masood Hamed Saghayan , Mohammad Hossein Zolfagharnasab , Ali Khadem , Farzam Matinfar , Hassan Rashidi

Purpose: The purpose is to design a novelty automatic diagnostic method for osteoporosis screening by using the potential capability of convolutional neural network (CNN) in feature representation and extraction, which can be incorporated…

Medical Physics · Physics 2019-10-16 Chao Tang , Wenkun Zhang , Haiting Li , Lei Li , Ziheng Li , Ailong Cai , Linyuan Wang , Dapeng Shi , Bin Yan

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Bias field, which is caused by imperfect MR devices or imaged objects, introduces intensity inhomogeneity into MR images and degrades the performance of MR image analysis methods. Many retrospective algorithms were developed to facilitate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Dong Liang , Xingyu Qiu , Kuanquan Wang , Gongning Luo , Wei Wang , Yashu Liu

Osteoporosis can be identified by looking at 2D x-ray images of the bone. The high degree of similarity between images of a healthy bone and a diseased one makes classification a challenge. A good bone texture characterization technique is…

Computer Vision and Pattern Recognition · Computer Science 2017-07-19 Rahul Paul , Saeed Alahamri , Sulav Malla , Ghulam Jilani Quadri

Many successful methods developed for medical image analysis that are based on machine learning use supervised learning approaches, which often require large datasets annotated by experts to achieve high accuracy. However, medical data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , David Cornell , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Background: MR-based subchondral bone effectively predicts knee osteoarthritis. However, its clinical application is limited by the cost and time of MR. Purpose: We aim to develop a novel distillation-learning-based method named SRRD for…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Yuqi Hu , Xiangyu Zhao , Gaowei Qing , Kai Xie , Chenglei Liu , Lichi Zhang

Lung diseases represent a significant global health challenge, with Chest X-Ray (CXR) being a key diagnostic tool due to its accessibility and affordability. Nonetheless, the detection of pulmonary lesions is often hindered by overlapping…

Image and Video Processing · Electrical Eng. & Systems 2025-07-10 Yifei Sun , Zhanghao Chen , Hao Zheng , Wenming Deng , Jin Liu , Wenwen Min , Ahmed Elazab , Xiang Wan , Changmiao Wang , Ruiquan Ge