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The US opioid overdose epidemic has been a major public health concern in recent decades. There has been increasing recognition that its etiology is rooted in part in the social contexts that mediate substance use and access; however,…

Social and Information Networks · Computer Science 2024-10-24 Kushagra Tiwari , M. Amin Rahimian , Mark S. Roberts , Praveen Kumar , Jeannine M. Buchanich

In the field of human-computer interaction (HCI), the usability assessment of m-learning (mobile-learning) applications is a real challenge. Such assessment typically involves extraction of the best features of an application like…

Human-Computer Interaction · Computer Science 2024-04-26 Muhammad Asghar , Imran Sarwar Bajwa , Shabana Ramzan , Hina Afreen , Saima Abdullah

Competing risk analysis considers event times due to multiple causes, or of more than one event types. Commonly used regression models for such data include 1) cause-specific hazards model, which focuses on modeling one type of event while…

Applications · Statistics 2017-04-27 Jiayi Hou , Anthony Paravati , Ronghui Xu , James Murphy

The United States (US) opioid crisis contributed to 81,806 fatalities in 2022. It has strained hospitals, treatment facilities, and law enforcement agencies due to the enormous resources and procedures needed to respond to the crisis. As a…

Computational Engineering, Finance, and Science · Computer Science 2025-07-14 Veronica M. White , Laura A. Albert

Alcohol misuse is a key target of public health strategies aimed at reducing cardiovascular risk. The effect of excessive alcohol consumption on blood pressure may vary systematically with individuals' unobserved propensity to engage in…

Methodology · Statistics 2026-03-11 Ashish Patel , Francis J DiTraglia , Stephen Burgess

Nowadays genetic algorithm (GA) is greatly used in engineering pedagogy as an adaptive technique to learn and solve complex problems and issues. It is a meta-heuristic approach that is used to solve hybrid computation challenges. GA…

Other Computer Science · Computer Science 2020-07-27 Tanweer Alam , Shamimul Qamar , Amit Dixit , Mohamed Benaida

Depression is a common yet serious mental disorder that affects millions of U.S. high schoolers every year. Still, accurate diagnosis and early detection remain significant challenges. In the field of public health, research shows that…

Machine Learning · Computer Science 2023-08-23 Nathan Zhong , Nikhil Yadav

This paper considers the use of machine learning algorithms for predicting cocaine use based on magnetic resonance imaging (MRI) connectomic data. The study utilized functional MRI (fMRI) and diffusion MRI (dMRI) data collected from 275…

Despite the massive costs and widespread harms of substance use, most individuals with substance use disorders (SUDs) receive no treatment at all. Digital therapeutics platforms are an emerging low-cost and low-barrier means of extending…

Systems and Control · Electrical Eng. & Systems 2025-04-03 Eric Pulick , Yonatan Mintz

The primary aim of this paper is to comprehend, assess, and analyze the role, relevance, and efficiency of machine learning models in predicting heart disease risks using clinical data. While the importance of heart disease risk prediction…

Machine Learning · Computer Science 2024-10-22 Balaji Shesharao Ingole , Vishnu Ramineni , Nikhil Bangad , Koushik Kumar Ganeeb , Priyankkumar Patel

Burnout is a psychological syndrome marked by emotional exhaustion, depersonalization, and reduced personal accomplishment, with a significant impact on individual well-being and organizational performance. This study proposes a machine…

Machine Learning · Computer Science 2025-10-30 Bruno W. G. Teodosio , Mário J. O. T. Lira , Pedro H. M. Araújo , Lucas R. C. Farias

Drug overdose deaths, including from opioids, remain a significant public health threat to the United States (US). To abate the harms of opioid misuse, understanding its prevalence at the local level is crucial for stakeholders in…

Applications · Statistics 2026-01-09 Zixuan Feng , Qiushi Chen , Paul Griffin , Le Bao

Background: Psychedelic drugs facilitate profound changes in consciousness and have potential to provide insights into the nature of human mental processes and their relation to brain physiology. Yet published scientific literature reflects…

Quantitative Methods · Quantitative Biology 2012-06-05 Jeremy R. Coyle , David E. Presti , Matthew J. Baggott

Cocaine addiction accounts for a large portion of substance use disorders and threatens millions of lives worldwide. There is an urgent need to come up with efficient anti-cocaine addiction drugs. Unfortunately, no medications have been…

Molecular Networks · Quantitative Biology 2021-09-21 Kaifu Gao , Dong Chen , Alfred J Robison , Guo-Wei Wei

Opioid use disorder (OUD) is a chronic and relapsing condition that involves the continued and compulsive use of opioids despite harmful consequences. The development of medications with improved efficacy and safety profiles for OUD…

Biomolecules · Quantitative Biology 2023-03-02 Hongsong Feng , Jian Jiang , Guo-Wei Wei

The complex unfolding of the US opioid epidemic in the last 20 years has been the subject of a large body of medical and pharmacological research, and it has sparked a multidisciplinary discussion on how to implement interventions and…

Computers and Society · Computer Science 2021-02-23 Duilio Balsamo , Paolo Bajardi , Alberto Salomone , Rossano Schifanella

Prescription opioids relieve moderate-to-severe pain after surgery, but overprescription can lead to misuse and overdose. Understanding factors associated with post-surgical opioid refills is crucial for improving pain management and…

Methodology · Statistics 2025-09-16 Eileen Yang , Donglin Zeng , Mark Bicket , Yi Li

The ongoing opioid crisis highlights the urgent need for novel therapeutic strategies that can be rapidly deployed. This study presents a novel approach to identify potential repurposable drugs for the treatment of opioid addiction, aiming…

Molecular Networks · Quantitative Biology 2025-09-25 Chunhuan Zhang , Sean Cottrell , Benjamin Jones , Yueying Zhu , Huahai Qiu , Bengong Zhang , Tianshou Zhou , Jian Jiang

Addiction epidemiology has been an active area of mathematical research in recent years. However, the social and mental processes involved in substance use disorders versus contraction of a pathogenic disease have presented challenges to…

Physics and Society · Physics 2022-02-25 Owen Queen , Vincent Jodoin , Leigh B. Pearcy , W. Christopher Strickland

The opioid epidemic, referring to the growing hospitalizations and deaths because of overdose of opioid usage and addiction, has become a severe health problem in the United States. Many strategies have been developed by the federal and…

Computation and Language · Computer Science 2024-09-11 Yuchen Wang , Zhengyu Fang , Wei Du , Shuai Xu , Rong Xu , Jing Li