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Opioid overdose has emerged as a full blown epidemic in the United States. In the last few years, there has been an alarming increase in Opioid related deaths, resulting in the loss of 63,600 lives in 2016 alone. The epidemic which is…

Computers and Society · Computer Science 2018-05-16 Kaustav Basu , Sandipan Choudhuri , Arunabha Sen , Aniket Majumdar

Drug overdose has become a public health crisis in the United States with devastating consequences. However, most of the drug overdose incidences are the consequence of recitative polysubstance usage over a defined period of time which can…

Artificial Intelligence · Computer Science 2022-04-13 Vaishali Mahipal , Mohammad Arif Ul Alam

Acute Myeloid Leukemia (AML) is a highly aggressive blood cancer with low survival rates. Hence, emphasizing the importance of the urgent need for effective treatment modalities. In recent times, the advances in cancer genomics have…

Other Quantitative Biology · Quantitative Biology 2025-12-09 Sadia Ruhama

Estimating the needs of healthcare products and inventory management are still challenging issues in hospitals nowadays. Centers are supposed to cope with tight budgets and patient satisfaction at the same time. Some issues can be tackled…

Computers and Society · Computer Science 2021-09-27 Denis Koala , Zakaria Yahouni , Gülgün Alpan , Yannick Frein

In recent years, machine learning has seen an increasing presencein a large variety of fields, especially in health care and bioinformatics.More specifically, the field where machine learning algorithms have found most applications is…

Neural and Evolutionary Computing · Computer Science 2020-08-21 Mekaal Swerhun , Jasmine Foley , Brandon Massop , Vijay Mago

The drug overdose crisis in the United States continues to intensify. Fatalities have increased five-fold since 1999 reaching a record high of 108,000 deaths in 2021. The epidemic has unfolded through distinct waves of different drug types,…

Applications · Statistics 2023-09-27 Lucas Böttcher , Tom Chou , Maria R. D'Orsogna

We describe two recently proposed machine learning approaches for discovering emerging trends in fatal accidental drug overdoses. The Gaussian Process Subset Scan enables early detection of emerging patterns in spatio-temporal data,…

Computers and Society · Computer Science 2017-10-09 Daniel B. Neill , William Herlands

Opioid use disorder (OUD) continuously poses major public health challenges and social implications worldwide with dramatic rise of opioid dependence leading to potential abuse. Despite that a few pharmacological agents have been approved…

Biomolecules · Quantitative Biology 2023-01-13 Hongsong Feng , Rana Elladki , Jian Jiang , Guo-Wei Wei

Substance use is a global issue that negatively impacts millions of persons who use drugs (PWUDs). In practice, identifying vulnerable PWUDs for efficient allocation of appropriate resources is challenging due to their complex use patterns…

Substance abuse is the unrestrained and detrimental use of psychoactive chemical substances, unauthorized drugs, and alcohol. Continuous use of these substances can ultimately lead a human to disastrous consequences. As patients display a…

Machine Learning · Computer Science 2021-01-12 Uwaise Ibna Islam , Iqbal H. Sarker , Enamul Haque , Mohammed Moshiul Hoque

This is a preprint version of the first book from the series: "Stories told by data". In this book a story is told about the psychological traits associated with drug consumption. The book includes: - A review of published works on the…

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being…

Artificial Intelligence · Computer Science 2021-03-30 Usha Lokala , Francois Lamy , Triyasha Ghosh Dastidar , Kaushik Roy , Raminta Daniulaityte , Srinivasan Parthasarathy , Amit Sheth

Vicodin is the most commonly prescribed pain reliever in the United States. Research indicates that there are two million people who are currently abusing Vicodin, and the majority of those who abuse Vicodin were initially exposed to it via…

Other Quantitative Biology · Quantitative Biology 2013-08-19 Wendy K. Caldwell , Benjamin Freedman , Luke Settles , Michael M. Thomas , Anarina Murillo , Erika Camacho , Stephen Wirkus

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Machine Learning · Computer Science 2020-05-01 Chirag Nagpal , Dennis Wei , Bhanukiran Vinzamuri , Monica Shekhar , Sara E. Berger , Subhro Das , Kush R. Varshney

Motivation: Opioid use disorder (OUD) often arises after prescription opioid exposure and follows transitions among onset, remission, and relapse. Linked EHR-survey resources such as the All of Us Research Program enable stage-specific risk…

Quantitative Methods · Quantitative Biology 2026-01-23 Mengman Wei , Stanislav Listopad , Qian Peng

Recently, a mathematical model describing the illicit drug consumption in a population consisting of drug users and non-users has been proposed. The model describes the dynamics of non-users, experimental users, recreational users, and…

Dynamical Systems · Mathematics 2019-08-07 Jean-Marc Ginoux , Roomila Naeck , Yusra Bibi Ruhomally , Muhammad Zaid Dauhoo , Matjaž Perc

We introduce a statistical agent based model to describe the phenomenon of drug abuse and its dynamical evolution at the individual and global level. The agents are heterogeneous with respect to their intrinsic inclination to drugs, to…

Physics and Society · Physics 2012-08-03 Riccardo Di Clemente , Luciano Pietronero

The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better…

Quantitative Methods · Quantitative Biology 2020-09-02 Ricky Wang

Predicting drug responses using genetic and transcriptomic features is crucial for enhancing personalized medicine. In this study, we implemented an ensemble of machine learning algorithms to analyze the correlation between genetic and…

Genomics · Quantitative Biology 2025-07-04 Johannes Schlüter , Alexander Schönhuth

Substance Use Disorders (SUDs) involve the misuse of any or several of a wide array of substances, such as alcohol, opioids, marijuana, and methamphetamine. SUDs are characterized by an inability to decrease use despite severe social,…

Computers and Society · Computer Science 2020-06-25 Lana Yarosh , Suzanne Bakken , Alan Borning , Munmun De Choudhury , Cliff Lampe , Elizabeth Mynatt , Stephen Schueller , Tiffany Veinot