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A treatment benefit predictor (TBP) is a function that maps patient characteristics to an estimate of the treatment benefit for that patient. Such predictors support optimizing individualized treatment decisions, which are central to…

Methodology · Statistics 2025-09-30 Yuan Xia , Mohsen Sadatsafavi , Paul Gustafson

This paper describes a Bayesian statistical method for determining the genetic basis of a complex genetic trait. The method uses a sample of unrelated individuals classified into two groups, for example cases and controls. Each group is…

Genomics · Quantitative Biology 2008-02-21 Toby Johnson

Risk prediction models are a crucial tool in healthcare. Risk prediction models with a binary outcome (i.e., binary classification models) are often constructed using methodology which assumes the costs of different classification errors…

Prediction is a central task of machine learning. Our goal is to solve large scale prediction problems using Generative Quantile Bayesian Prediction (GQBP).By directly learning predictive quantiles rather than densities we achieve a number…

Methodology · Statistics 2025-10-28 Maria Nareklishvili , Nick Polson , Vadim Sokolov

We examine a probabilistic model for the diagnosis of multiple diseases. In the model, diseases and findings are represented as binary variables. Also, diseases are marginally independent, features are conditionally independent given…

Artificial Intelligence · Computer Science 2022-12-07 David Heckerman

Deploying deep models in real-world scenarios entails a number of challenges, including computational efficiency and real-world (e.g., long-tailed) data distributions. We address the combined challenge of learning long-tailed distributions…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Jihun Kim , Dahyun Kim , Hyungrok Jung , Taeil Oh , Jonghyun Choi

Our work focuses on tackling the challenging but natural visual recognition task of long-tailed data distribution (i.e., a few classes occupy most of the data, while most classes have rarely few samples). In the literature, class…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Boyan Zhou , Quan Cui , Xiu-Shen Wei , Zhao-Min Chen

This paper surveys the data-driven dose prediction approaches introduced for knowledge-based planning (KBP) in the last decade. These methods were classified into two major categories according to their methods and techniques of utilizing…

Bilevel programs (BPs) find a wide range of applications in fields such as energy, transportation, and machine learning. As compared to BPs with continuous (linear/convex) optimization problems in both levels, the BPs with discrete decision…

Optimization and Control · Mathematics 2024-07-25 Bo Zhou , Ruiwei Jiang , Siqian Shen

Statistical methods for analyzing large-scale biomolecular data are commonplace in computational biology. A notable example is phenotype prediction from gene expression data, for instance, detecting human cancers, differentiating subtypes…

Genomics · Quantitative Biology 2014-11-24 Bahman Afsari , Ulisses M. Braga-Neto , Donald Geman

This paper proposes a specification test for the conventional distributional assumptions of error terms in binary choice models, focusing on its tail properties. Based on extreme value theory, we first establish that the tail index of the…

Econometrics · Economics 2026-03-31 Ting Ji , Laura Liu , Yulong Wang , Jiahe Xing

Causal inference for extreme events has many potential applications in fields such as climate science, medicine and economics. We study the extremal quantile treatment effect of a binary treatment on a continuous, heavy-tailed outcome.…

Methodology · Statistics 2023-07-06 David Deuber , Jinzhou Li , Sebastian Engelke , Marloes H. Maathuis

A pressing challenge in medical research is to identify optimal treatments for individual patients. This is particularly challenging in mental health settings where mean responses are often similar across multiple treatments. For example,…

Methodology · Statistics 2022-03-08 Lanqiu Yao , Thaddeus Tarpey

The adequate use of information measured in a continuous manner along a period of time represents a methodological challenge. In the last decades, most of traditional statistical procedures have been extended for accommodating these…

Methodology · Statistics 2025-12-04 Pablo Martinez-Camblor

Scientific claim verification is a unique challenge that is attracting increasing interest. The SCIVER shared task offers a benchmark scenario to test and compare claim verification approaches by participating teams and consists in three…

Computation and Language · Computer Science 2021-04-26 Xia Zeng , Arkaitz Zubiaga

Bayesian decision theory advocates the Bayes classifier as the optimal approach for minimizing the risk in machine learning problems. Current deep learning algorithms usually solve for the optimal classifier by \emph{implicitly} estimating…

Machine Learning · Computer Science 2025-07-01 Chaoqun Du , Yulin Wang , Shiji Song , Gao Huang

We propose a quantum representation of binary classification trees with binary features based on a probabilistic approach. By using the quantum computer as a processor for probability distributions, a probabilistic traversal of the decision…

Quantum Physics · Physics 2022-08-23 Raoul Heese , Patricia Bickert , Astrid Elisa Niederle

Long-tailed classification is challenging due to its heavy imbalance in class probabilities. While existing methods often focus on overall accuracy or accuracy for tail classes, they overlook a critical aspect: certain types of errors can…

Machine Learning · Computer Science 2025-01-27 Bolian Li , Ruqi Zhang

Long-tailed instance segmentation is a challenging task due to the extreme imbalance of training samples among classes. It causes severe biases of the head classes (with majority samples) against the tailed ones. This renders "how to…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Yin-Yin He , Peizhen Zhang , Xiu-Shen Wei , Xiangyu Zhang , Jian Sun

Scientific studies in the last two decades have established the central role of the microbiome in disease and health. Differential abundance analysis seeks to identify microbial taxa associated with sample groups defined by a factor such as…

Methodology · Statistics 2023-12-29 Archie Sachdeva , Somnath Datta , Subharup Guha
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