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The rapid growth of Large Language Models (LLMs) has been a driving force in transforming various domains, reshaping the artificial general intelligence landscape. However, the increasing computational and memory demands of these models…

Computation and Language · Computer Science 2024-04-22 Tianyu Ding , Tianyi Chen , Haidong Zhu , Jiachen Jiang , Yiqi Zhong , Jinxin Zhou , Guangzhi Wang , Zhihui Zhu , Ilya Zharkov , Luming Liang

This work presents an analytical framework for the design and analysis of LLM-based algorithms, i.e., algorithms that contain one or multiple calls of large language models (LLMs) as sub-routines and critically rely on the capabilities of…

Machine Learning · Computer Science 2025-10-14 Yanxi Chen , Yaliang Li , Bolin Ding , Jingren Zhou

Large Language Models (LLMs) have demonstrated promise in medical knowledge assessments, yet their practical utility in real-world clinical decision-making remains underexplored. In this study, we evaluated the performance of three…

Computation and Language · Computer Science 2025-12-30 Mengdi Chai , Ali R. Zomorrodi

Access to large amounts of diverse design solutions can support designers during the early stage of the design process. In this paper, we explore the efficacy of large language models (LLM) in producing diverse design solutions,…

Human-Computer Interaction · Computer Science 2024-05-07 Kevin Ma , Daniele Grandi , Christopher McComb , Kosa Goucher-Lambert

Generalized linear models (GLMs) are popular for data-analysis in almost all quantitative sciences, but the choice of likelihood family and link function is often difficult. This motivates the search for likelihoods and links that minimize…

Methodology · Statistics 2024-03-19 Maximilian Scholz , Paul-Christian Bürkner

The advancement of Large Language Models (LLMs), including GPT-4, provides exciting new opportunities for generative design. We investigate the application of this tool across the entire design and manufacturing workflow. Specifically, we…

Regularized linear models, such as Lasso, have attracted great attention in statistical learning and data science. However, there is sporadic work on constructing efficient data collection for regularized linear models. In this work, we…

Methodology · Statistics 2021-04-06 C. Devon Lin , Peter Chien , Xinwei Deng

A common challenge in computer experiments and related fields is to efficiently explore the input space using a small number of samples, i.e., the experimental design problem. Much of the recent focus in the computer experiment literature,…

Methodology · Statistics 2019-07-01 Boya Zhang , D. Austin Cole , Robert B. Gramacy

Benchmarks have emerged as the central approach for evaluating Large Language Models (LLMs). The research community often relies on a model's average performance across the test prompts of a benchmark to evaluate the model's performance.…

Computation and Language · Computer Science 2024-06-07 Melissa Ailem , Katerina Marazopoulou , Charlotte Siska , James Bono

Unit testing plays a pivotal role in software development, improving software quality and reliability. However, generating effective test cases manually is time-consuming, prompting interest in unit testing research. Recently, Large…

Software Engineering · Computer Science 2024-12-24 Ye Shang , Quanjun Zhang , Chunrong Fang , Siqi Gu , Jianyi Zhou , Zhenyu Chen

Pilot studies are highly recommended in experiments with animals when little is known about the anticipated values of the mean of the variable under study, its variance or the probability of response. They are also recommended to test the…

Applications · Statistics 2018-03-20 C. O. S. Sorzano , D. Tabas-Madrid , F. Núñez , C. Fernández-Criado , A. Naranjo

Due to the ease of modern data collection, applied statisticians often have access to a large set of covariates that they wish to relate to some observed outcome. Generalized linear models (GLMs) offer a particularly interpretable framework…

Computation · Statistics 2019-05-21 Brian L. Trippe , Jonathan H. Huggins , Raj Agrawal , Tamara Broderick

We consider the problem of constructing optimal designs for population pharmacokinetics which use random effect models. It is common practice in the design of experiments in such studies to assume uncorrelated errors for each subject. In…

Applications · Statistics 2010-11-16 Holger Dette , Andrey Pepelyshev , Tim Holland-Letz

When observations are independent, formulae and software are readily available to plan and design studies of appropriate size and power to detect important associations. When observations are correlated or clustered, results obtained from…

Applications · Statistics 2021-03-15 David M. Thompson

Statistical significance testing of neural coherence is essential for distinguishing genuine cross-signal coupling from spurious correlations. A widely accepted approach uses surrogate-based inference, where null distributions are generated…

Signal Processing · Electrical Eng. & Systems 2026-05-13 Md Rakibul Mowla , Sukhbinder Kumar , Ariane E. Rhone , Brian J. Dlouhy , Christopher K. Kovach

Learning for control in repeated tasks allows for well-designed experiments to gather the most useful data. We consider the setting in which we use a data-driven controller that does not have access to the true system dynamics. Rather, the…

Systems and Control · Electrical Eng. & Systems 2025-02-21 Sean Anderson , Katie Byl , João P. Hespanha

This paper considers generalized linear models using rule-based features, also referred to as rule ensembles, for regression and probabilistic classification. Rules facilitate model interpretation while also capturing nonlinear dependences…

Machine Learning · Computer Science 2019-06-06 Dennis Wei , Sanjeeb Dash , Tian Gao , Oktay Günlük

Algorithms for machine learning-guided design, or design algorithms, use machine learning-based predictions to propose novel objects with desired property values. Given a new design task -- for example, to design novel proteins with high…

Machine Learning · Computer Science 2025-07-04 Clara Fannjiang , Ji Won Park

For a partially unknown linear systems, we present a systematic control design approach based on generated data from measurements of closed-loop experiments with suitable test controllers. These experiments are used to improve the achieved…

Optimization and Control · Mathematics 2022-05-12 Tobias Holicki , Carsten W. Scherer , Sebastian Trimpe

Molecular design involves an enormous and irregular search space, where traditional optimizers such as Bayesian optimization, genetic algorithms, and generative models struggle to leverage expert knowledge or handle complex feedback.…

Machine Learning · Computer Science 2025-12-09 Nian Ran , Yue Wang , Xiaoyuan Zhang , Zhongzheng Li , Qingsong Ran , Wenhao Li , Richard Allmendinger
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