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The Area Under the ROC Curve (AUC) is a key metric for classification, especially under class imbalance, with growing research focus on optimizing AUC over accuracy in applications like medical image analysis and deepfake detection. This…

Machine Learning · Computer Science 2025-05-27 Mingyang Wu , Li Lin , Wenbin Zhang , Xin Wang , Zhenhuan Yang , Shu Hu

Many typical applications of object detection operate within a prescribed false-positive range. In this situation the performance of a detector should be assessed on the basis of the area under the ROC curve over that range, rather than…

Computer Vision and Pattern Recognition · Computer Science 2013-10-04 Sakrapee Paisitkriangkrai , Chunhua Shen , Anton van den Hengel

Diagnostic tests are of critical importance in health care and medical research. Motivated by the impact that atypical and outlying test outcomes might have on the assessment of the discriminatory ability of a diagnostic test, we develop a…

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Anomaly Detection is a crucial step for critical applications such in the industrial, medical or cybersecurity domains. These sectors share the same requirement of handling differently the different types of classification errors. Indeed,…

Machine Learning · Computer Science 2025-04-03 Arnaud Bougaham , Benoît Frénay

Algorithmic bias continues to be a key concern of learning analytics. We study the statistical properties of the Absolute Between-ROC Area (ABROCA) metric. This fairness measure quantifies group-level differences in classifier performance…

Machine Learning · Statistics 2024-12-02 Conrad Borchers , Ryan S. Baker

The Area Under the ROC Curve (AUC) is an important model metric for evaluating binary classifiers, and many algorithms have been proposed to optimize AUC approximately. It raises the question of whether the generally insignificant gains…

Computational Geometry · Computer Science 2023-06-05 Baojian Zhou , Steven Skiena

We study fairness in the context of classification where the performance is measured by the area under the curve (AUC) of the receiver operating characteristic. AUC is commonly used to measure the performance of prediction models. The same…

Machine Learning · Computer Science 2022-08-25 Hortense Fong , Vineet Kumar , Anay Mehrotra , Nisheeth K. Vishnoi

The Area under the ROC curve (AUC) is a well-known ranking metric for problems such as imbalanced learning and recommender systems. The vast majority of existing AUC-optimization-based machine learning methods only focus on binary-class…

Machine Learning · Computer Science 2021-07-29 Zhiyong Yang , Qianqian Xu , Shilong Bao , Xiaochun Cao , Qingming Huang

Objective: Area under the receiving operator characteristic curve (AUC) is commonly reported alongside prediction models for binary outcomes. Recent articles have raised concerns that AUC might be a misleading measure of prediction…

Machine Learning · Statistics 2025-11-04 Emily Minus , R. Yates Coley , Susan M. Shortreed , Brian D. Williamson

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Muhaisin Tiyumba Nantogmah , Abdul-Barik Alhassan , Salamudeen Alhassan

Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley

Prediction uncertainty estimation has clinical significance as it can potentially quantify prediction reliability. Clinicians may trust 'blackbox' models more if robust reliability information is available, which may lead to more models…

Machine Learning · Computer Science 2022-10-04 Michael Dohopolski , Kai Wang , Biling Wang , Ti Bai , Dan Nguyen , David Sher , Steve Jiang , Jing Wang

Computer-aided drug discovery is an essential component of modern drug development. Therein, deep learning has become an important tool for rapid screening of billions of molecules in silico for potential hits containing desired chemical…

Area under the ROC curve (AUC) optimisation techniques developed for neural networks have recently demonstrated their capabilities in different audio and speech related tasks. However, due to its intrinsic nature, AUC optimisation has…

Sound · Computer Science 2021-10-28 Pablo Gimeno , Victoria Mingote , Alfonso Ortega , Antonio Miguel , Eduardo Lleida

To assess the classification accuracy of a continuous diagnostic result, the receiver operating characteristic (ROC) curve is commonly used in applications. The partial area under the ROC curve (pAUC) is one of widely accepted summary…

Applications · Statistics 2011-03-11 Hung Hung , Chin-Tsang Chiang

Rigorous external validation is crucial for assessing the generalizability of prediction models, particularly by evaluating their discrimination (AUROC) on new data. This often involves comparing a new model's AUROC to that of an…

Methodology · Statistics 2025-01-07 François Grolleau , Robert Tibshirani , Jonathan H. Chen

Objectives: Estimation of areas under receiver operating characteristic curves (AUCs) and their differences is a key task in diagnostic studies. We aimed to derive, evaluate, and implement simple sample size formulas for such studies with a…

Methodology · Statistics 2022-08-03 Di Shu , Guangyong Zou

The use of machine learning models in consequential decision making often exacerbates societal inequity, in particular yielding disparate impact on members of marginalized groups defined by race and gender. The area under the ROC curve…

Machine Learning · Computer Science 2022-11-30 Zhenhuan Yang , Yan Lok Ko , Kush R. Varshney , Yiming Ying